suramin sodium-7529 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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196 genes differentially expressed following the suramin sodium-7529 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM12 ADAM metallopeptidase domain 12
AHCYL2 adenosylhomocysteinase-like 2
ALDH4A1 aldehyde dehydrogenase 4 family, member A1
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ANXA2P1 annexin A2 pseudogene 1
B3GALT4 UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 4
BAIAP2 BAI1-associated protein 2
BATF3 basic leucine zipper transcription factor, ATF-like 3
BMP1 bone morphogenetic protein 1
BMP4 bone morphogenetic protein 4
BRCA1 breast cancer 1, early onset
BTBD7 BTB (POZ) domain containing 7
BTN2A1 butyrophilin, subfamily 2, member A1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C16ORF59 chromosome 16 open reading frame 59
C17ORF70 chromosome 17 open reading frame 70
C7ORF43 chromosome 7 open reading frame 43
CDK3 cyclin-dependent kinase 3
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CPQ carboxypeptidase Q
CREB1 cAMP responsive element binding protein 1
CTAGE5 CTAGE family, member 5
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DGCR2 DiGeorge syndrome critical region gene 2
DHRS2 dehydrogenase/reductase (SDR family) member 2
ECE1 endothelin converting enzyme 1
EGFR epidermal growth factor receptor
EMP1 epithelial membrane protein 1
EPN1 epsin 1
ESM1 endothelial cell-specific molecule 1
EVI5 ecotropic viral integration site 5
F3 coagulation factor III (thromboplastin, tissue factor)
FGFR1OP FGFR1 oncogene partner
FH fumarate hydratase
FKBP10 FK506 binding protein 10, 65 kDa
GALK2 galactokinase 2
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPALPP1 GPALPP motifs containing 1
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
HUS1 HUS1 checkpoint homolog (S. pombe)
IL27RA interleukin 27 receptor, alpha
IREB2 iron-responsive element binding protein 2
ITGB1 integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
KDM4C lysine (K)-specific demethylase 4C
KLHL22 kelch-like family member 22
LMAN1 lectin, mannose-binding, 1
LMNA lamin A/C
LTB4R leukotriene B4 receptor
MCM3AP minichromosome maintenance complex component 3 associated protein
MCTP2 multiple C2 domains, transmembrane 2
MRPS12 mitochondrial ribosomal protein S12
MTM1 myotubularin 1
NADK NAD kinase
NF2 neurofibromin 2 (merlin)
NFYA nuclear transcription factor Y, alpha
NPAS2 neuronal PAS domain protein 2
NUP160 nucleoporin 160kDa
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSTF1 osteoclast stimulating factor 1
PAFAH2 platelet-activating factor acetylhydrolase 2, 40kDa
PALMD palmdelphin
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PFDN4 prefoldin subunit 4
PGK1 phosphoglycerate kinase 1
PLXNA3 plexin A3
PLXND1 plexin D1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
POLH polymerase (DNA directed), eta
POLL polymerase (DNA directed), lambda
PTPN18 protein tyrosine phosphatase, non-receptor type 18 (brain-derived)
RARG retinoic acid receptor, gamma
RNF126P1 ring finger protein 126 pseudogene 1
RRNAD1 ribosomal RNA adenine dimethylase domain containing 1
SCARB1 scavenger receptor class B, member 1
SCIN scinderin
SFTPB surfactant protein B
SIRT2 sirtuin 2
SLC19A1 solute carrier family 19 (folate transporter), member 1
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SMURF1 SMAD specific E3 ubiquitin protein ligase 1
SOX4 SRY (sex determining region Y)-box 4
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
TDRD3 tudor domain containing 3
TECPR2 tectonin beta-propeller repeat containing 2
THBS3 thrombospondin 3
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TOLLIP toll interacting protein
TOP3B topoisomerase (DNA) III beta
TRAF4 TNF receptor-associated factor 4
TRIM25 tripartite motif containing 25
TRIM45 tripartite motif containing 45
TSC22D4 TSC22 domain family, member 4
TWF1 twinfilin actin binding protein 1
VEGFA vascular endothelial growth factor A
VPS13D vacuolar protein sorting 13 homolog D (S. cerevisiae)
WDR1 WD repeat domain 1
XYLT2 xylosyltransferase II

decreased expression

Symbol Name
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AIM1L absent in melanoma 1-like
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
APOL6 apolipoprotein L, 6
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ATG2B autophagy related 2B
AXIN1 axin 1
BAX BCL2-associated X protein
BCAS3 breast carcinoma amplified sequence 3
BEX1 brain expressed, X-linked 1
C14ORF79 chromosome 14 open reading frame 79
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C5ORF45 chromosome 5 open reading frame 45
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1)
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COL9A3 collagen, type IX, alpha 3
COQ3 coenzyme Q3 methyltransferase
CORT cortistatin
CRISP2 cysteine-rich secretory protein 2
CRYGC crystallin, gamma C
CTC1 CTS telomere maintenance complex component 1
CUZD1 CUB and zona pellucida-like domains 1
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
CYP2R1 cytochrome P450, family 2, subfamily R, polypeptide 1
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DTX2 deltex 2, E3 ubiquitin ligase
EIF5A2 eukaryotic translation initiation factor 5A2
EYA4 EYA transcriptional coactivator and phosphatase 4
GAL3ST4 galactose-3-O-sulfotransferase 4
GMEB1 glucocorticoid modulatory element binding protein 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
GPR3 G protein-coupled receptor 3
GRAMD4 GRAM domain containing 4
GSTCD glutathione S-transferase, C-terminal domain containing
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HERC6 HECT and RLD domain containing E3 ubiquitin protein ligase family member 6
HIRA histone cell cycle regulator
HIST1H2AJ histone cluster 1, H2aj
IFT81 intraflagellar transport 81
IGBP1 immunoglobulin (CD79A) binding protein 1
IL12A interleukin 12A
IL4R interleukin 4 receptor
IQCC IQ motif containing C
KCNK12 potassium channel, two pore domain subfamily K, member 12
KIF16B kinesin family member 16B
KIFC1 kinesin family member C1
KRT86 keratin 86, type II
LGALS4 lectin, galactoside-binding, soluble, 4
LMCD1 LIM and cysteine-rich domains 1
LMNB1 lamin B1
LRP5L low density lipoprotein receptor-related protein 5-like
MCTP1 multiple C2 domains, transmembrane 1
MEGF8 multiple EGF-like-domains 8
MFHAS1 malignant fibrous histiocytoma amplified sequence 1
MMP17 matrix metallopeptidase 17 (membrane-inserted)
MYH15 myosin, heavy chain 15
MYO1F myosin IF
NCS1 neuronal calcium sensor 1
NPFFR1 neuropeptide FF receptor 1
NUPL2 nucleoporin like 2
NYNRIN NYN domain and retroviral integrase containing
ODF2 outer dense fiber of sperm tails 2
OLFML2B olfactomedin-like 2B
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PALM paralemmin
PLAC1 placenta-specific 1
PLXNB3 plexin B3
PTGER2 prostaglandin E receptor 2 (subtype EP2), 53kDa
PTPRU protein tyrosine phosphatase, receptor type, U
RAVER2 ribonucleoprotein, PTB-binding 2
RIBC2 RIB43A domain with coiled-coils 2
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
SCG5 secretogranin V
SERGEF secretion regulating guanine nucleotide exchange factor
SETD6 SET domain containing 6
SLC4A3 solute carrier family 4 (anion exchanger), member 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SMO smoothened, frizzled class receptor
SPATA2L spermatogenesis associated 2-like
SPIDR scaffolding protein involved in DNA repair
STIM1 stromal interaction molecule 1
TAGLN3 transgelin 3
TBC1D22B TBC1 domain family, member 22B
TESK2 testis-specific kinase 2
TUBB2B tubulin, beta 2B class IIb
USP19 ubiquitin specific peptidase 19
WNT7A wingless-type MMTV integration site family, member 7A
ZNF358 zinc finger protein 358
ZNF702P zinc finger protein 702, pseudogene
ZNF749 zinc finger protein 749
ZNF770 zinc finger protein 770
ZXDC ZXD family zinc finger C