suramin sodium-7501 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the suramin sodium-7501 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY1 adenylate cyclase 1 (brain)
AGGF1 angiogenic factor with G patch and FHA domains 1
ARFRP1 ADP-ribosylation factor related protein 1
ARHGEF11 Rho guanine nucleotide exchange factor (GEF) 11
ARL14 ADP-ribosylation factor-like 14
ASB1 ankyrin repeat and SOCS box containing 1
AVPR1A arginine vasopressin receptor 1A
BLZF1 basic leucine zipper nuclear factor 1
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
CASZ1 castor zinc finger 1
CDC40 cell division cycle 40
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDK3 cyclin-dependent kinase 3
CPPED1 calcineurin-like phosphoesterase domain containing 1
CTSD cathepsin D
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DBP D site of albumin promoter (albumin D-box) binding protein
DCLRE1A DNA cross-link repair 1A
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
DENND2A DENN/MADD domain containing 2A
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
ELMO2 engulfment and cell motility 2
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
FAM53B family with sequence similarity 53, member B
FAS Fas cell surface death receptor
FGFR1 fibroblast growth factor receptor 1
FGFR2 fibroblast growth factor receptor 2
FOXG1 forkhead box G1
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
FUZ fuzzy planar cell polarity protein
FYB FYN binding protein
GLCE glucuronic acid epimerase
GPR161 G protein-coupled receptor 161
GSTA1 glutathione S-transferase alpha 1
HDAC9 histone deacetylase 9
HNMT histamine N-methyltransferase
HOXB6 homeobox B6
HSPB11 heat shock protein family B (small), member 11
IL1RAP interleukin 1 receptor accessory protein
ING4 inhibitor of growth family, member 4
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
IQCE IQ motif containing E
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF4 interferon regulatory factor 4
KAT5 K(lysine) acetyltransferase 5
KDM4B lysine (K)-specific demethylase 4B
LAMC2 laminin, gamma 2
LIG3 ligase III, DNA, ATP-dependent
LIG4 ligase IV, DNA, ATP-dependent
LMF1 lipase maturation factor 1
LOC644450 uncharacterized LOC644450
LYPD3 LY6/PLAUR domain containing 3
LYST lysosomal trafficking regulator
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MAOA monoamine oxidase A
MAP2K7 mitogen-activated protein kinase kinase 7
MKL1 megakaryoblastic leukemia (translocation) 1
MMP9 matrix metallopeptidase 9
MXRA8 matrix-remodelling associated 8
NCAPH2 non-SMC condensin II complex, subunit H2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NF2 neurofibromin 2 (merlin)
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PCBP4 poly(rC) binding protein 4
PDGFB platelet-derived growth factor beta polypeptide
PHC1 polyhomeotic homolog 1 (Drosophila)
PLK3 polo-like kinase 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PTK6 protein tyrosine kinase 6
R3HDM1 R3H domain containing 1
RBM3 RNA binding motif (RNP1, RRM) protein 3
RNF41 ring finger protein 41, E3 ubiquitin protein ligase
RUNX1 runt-related transcription factor 1
SCARB2 scavenger receptor class B, member 2
SGSM3 small G protein signaling modulator 3
SIDT2 SID1 transmembrane family, member 2
SIRT6 sirtuin 6
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC38A7 solute carrier family 38, member 7
SLC43A3 solute carrier family 43, member 3
SPO11 SPO11 meiotic protein covalently bound to DSB
SWAP70 SWAP switching B-cell complex 70kDa subunit
TAGLN3 transgelin 3
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box)
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TREX1 three prime repair exonuclease 1
TTLL5 tubulin tyrosine ligase-like family member 5
UTY ubiquitously transcribed tetratricopeptide repeat containing, Y-linked
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
WIPI1 WD repeat domain, phosphoinositide interacting 1
WIZ widely interspaced zinc finger motifs
ZBTB39 zinc finger and BTB domain containing 39
ZMYND8 zinc finger, MYND-type containing 8
ZNF552 zinc finger protein 552
ZNF574 zinc finger protein 574

decreased expression

Symbol Name
ADAM15 ADAM metallopeptidase domain 15
ALPK1 alpha-kinase 1
AMDHD2 amidohydrolase domain containing 2
ANKFY1 ankyrin repeat and FYVE domain containing 1
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
APOH apolipoprotein H (beta-2-glycoprotein I)
ARHGEF10L Rho guanine nucleotide exchange factor (GEF) 10-like
ARMC4 armadillo repeat containing 4
ARSB arylsulfatase B
ATXN8OS ATXN8 opposite strand (non-protein coding)
BATF3 basic leucine zipper transcription factor, ATF-like 3
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTN2A3P butyrophilin, subfamily 2, member A3, pseudogene
BTNL3 butyrophilin-like 3
CADPS2 Ca++-dependent secretion activator 2
CCRL2 chemokine (C-C motif) receptor-like 2
CELSR2 cadherin, EGF LAG seven-pass G-type receptor 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLTCL1 clathrin, heavy chain-like 1
CUZD1 CUB and zona pellucida-like domains 1
CXCL3 chemokine (C-X-C motif) ligand 3
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1
CYP2W1 cytochrome P450, family 2, subfamily W, polypeptide 1
DBNDD1 dysbindin (dystrobrevin binding protein 1) domain containing 1
DEPTOR DEP domain containing MTOR-interacting protein
DIO3 deiodinase, iodothyronine, type III
DLL3 delta-like 3 (Drosophila)
DUSP8 dual specificity phosphatase 8
EPHA4 EPH receptor A4
EPN1 epsin 1
ETV7 ets variant 7
EXD3 exonuclease 3'-5' domain containing 3
FAM186A family with sequence similarity 186, member A
FANCF Fanconi anemia, complementation group F
FTCD formimidoyltransferase cyclodeaminase
FZD10 frizzled class receptor 10
GLS2 glutaminase 2 (liver, mitochondrial)
GNA13 guanine nucleotide binding protein (G protein), alpha 13
GPATCH3 G patch domain containing 3
GPR3 G protein-coupled receptor 3
GRTP1 growth hormone regulated TBC protein 1
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
IFI6 interferon, alpha-inducible protein 6
IL17RB interleukin 17 receptor B
INF2 inverted formin, FH2 and WH2 domain containing
KCNK13 potassium channel, two pore domain subfamily K, member 13
KDM8 lysine (K)-specific demethylase 8
KLHL25 kelch-like family member 25
KLHL28 kelch-like family member 28
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MCM9 minichromosome maintenance complex component 9
MOCS3 molybdenum cofactor synthesis 3
MRAS muscle RAS oncogene homolog
MX1 MX dynamin-like GTPase 1
MX2 MX dynamin-like GTPase 2
MYBPC3 myosin binding protein C, cardiac
MYO1F myosin IF
MYRIP myosin VIIA and Rab interacting protein
NRSN2 neurensin 2
NXPH4 neurexophilin 4
OSGIN1 oxidative stress induced growth inhibitor 1
OTUD3 OTU deubiquitinase 3
PEX26 peroxisomal biogenesis factor 26
PIGQ phosphatidylinositol glycan anchor biosynthesis, class Q
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLXNA3 plexin A3
POLM polymerase (DNA directed), mu
PSORS1C1 psoriasis susceptibility 1 candidate 1
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RABL6 RAB, member RAS oncogene family-like 6
RPAP2 RNA polymerase II associated protein 2
SCD5 stearoyl-CoA desaturase 5
SETD1A SET domain containing 1A
SH2D2A SH2 domain containing 2A
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SOX12 SRY (sex determining region Y)-box 12
SPAG7 sperm associated antigen 7
SPIDR scaffolding protein involved in DNA repair
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
THOC6 THO complex 6
TMEM159 transmembrane protein 159
TMEM180 transmembrane protein 180
TMEM57 transmembrane protein 57
UNC93B1 unc-93 homolog B1 (C. elegans)
USP19 ubiquitin specific peptidase 19
USP20 ubiquitin specific peptidase 20
VGF VGF nerve growth factor inducible
YPEL1 yippee-like 1 (Drosophila)
YY2 YY2 transcription factor
ZMAT5 zinc finger, matrin-type 5
ZNF137P zinc finger protein 137, pseudogene
ZNF280D zinc finger protein 280D
ZNF286A zinc finger protein 286A
ZNF415 zinc finger protein 415
ZNF492 zinc finger protein 492
ZNF862 zinc finger protein 862