suprofen-4123 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the suprofen-4123 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACPP acid phosphatase, prostate
ADGRL1 adhesion G protein-coupled receptor L1
AGFG2 ArfGAP with FG repeats 2
ANKRD55 ankyrin repeat domain 55
APAF1 apoptotic peptidase activating factor 1
ARMC4 armadillo repeat containing 4
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP9B ATPase, class II, type 9B
C1ORF95 chromosome 1 open reading frame 95
CACNA1H calcium channel, voltage-dependent, T type, alpha 1H subunit
CAMK4 calcium/calmodulin-dependent protein kinase IV
CASP10 caspase 10, apoptosis-related cysteine peptidase
CCZ1 CCZ1 vacuolar protein trafficking and biogenesis associated homolog (S. cerevisiae)
CEND1 cell cycle exit and neuronal differentiation 1
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CLEC4E C-type lectin domain family 4, member E
COMT catechol-O-methyltransferase
CRY2 cryptochrome circadian clock 2
CXCR6 chemokine (C-X-C motif) receptor 6
CYB5A cytochrome b5 type A (microsomal)
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
CYTH1 cytohesin 1
DFNB31 deafness, autosomal recessive 31
DGKQ diacylglycerol kinase, theta 110kDa
DMXL2 Dmx-like 2
DTX2 deltex 2, E3 ubiquitin ligase
ETV5 ets variant 5
FBLN1 fibulin 1
FBN1 fibrillin 1
FBXO2 F-box protein 2
FGD1 FYVE, RhoGEF and PH domain containing 1
GNG11 guanine nucleotide binding protein (G protein), gamma 11
GSTCD glutathione S-transferase, C-terminal domain containing
HCFC1 host cell factor C1
HCN2 hyperpolarization activated cyclic nucleotide gated potassium channel 2
HCN4 hyperpolarization activated cyclic nucleotide gated potassium channel 4
HIPK2 homeodomain interacting protein kinase 2
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HPX hemopexin
HS6ST1 heparan sulfate 6-O-sulfotransferase 1
HSPG2 heparan sulfate proteoglycan 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IBTK inhibitor of Bruton agammaglobulinemia tyrosine kinase
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IKZF1 IKAROS family zinc finger 1 (Ikaros)
INE1 inactivation escape 1 (non-protein coding)
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
KIAA0319L KIAA0319-like
KIAA1107 KIAA1107
LIMCH1 LIM and calponin homology domains 1
LPCAT4 lysophosphatidylcholine acyltransferase 4
MIIP migration and invasion inhibitory protein
MMP11 matrix metallopeptidase 11
MMP14 matrix metallopeptidase 14 (membrane-inserted)
MSI1 musashi RNA-binding protein 1
MYOZ3 myozenin 3
NAB1 NGFI-A binding protein 1 (EGR1 binding protein 1)
NBL1 neuroblastoma 1, DAN family BMP antagonist
NCKIPSD NCK interacting protein with SH3 domain
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NMNAT2 nicotinamide nucleotide adenylyltransferase 2
NR4A2 nuclear receptor subfamily 4, group A, member 2
NUDT11 nudix (nucleoside diphosphate linked moiety X)-type motif 11
OR7A17 olfactory receptor, family 7, subfamily A, member 17
PCDH9 protocadherin 9
PCSK6 proprotein convertase subtilisin/kexin type 6
PDCD2 programmed cell death 2
PLEKHA2 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 2
PLLP plasmolipin
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASIP1 Ras interacting protein 1
RECQL5 RecQ protein-like 5
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
SAG S-antigen; retina and pineal gland (arrestin)
SAMD4A sterile alpha motif domain containing 4A
SECTM1 secreted and transmembrane 1
SFTPB surfactant protein B
SIK3 SIK family kinase 3
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
SOCS7 suppressor of cytokine signaling 7
SOX2 SRY (sex determining region Y)-box 2
SPON1 spondin 1, extracellular matrix protein
SSPN sarcospan
SUGP1 SURP and G patch domain containing 1
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4)
TIMP3 TIMP metallopeptidase inhibitor 3
TRIM29 tripartite motif containing 29
TUBA3C tubulin, alpha 3c
UBA6 ubiquitin-like modifier activating enzyme 6
UHRF1BP1L UHRF1 binding protein 1-like
USP46 ubiquitin specific peptidase 46
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase
ZNF551 zinc finger protein 551
ZSWIM1 zinc finger, SWIM-type containing 1

decreased expression

Symbol Name
A2M alpha-2-macroglobulin
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADGRE5 adhesion G protein-coupled receptor E5
ALS2CL ALS2 C-terminal like
AMH anti-Mullerian hormone
B9D2 B9 protein domain 2
BTN2A2 butyrophilin, subfamily 2, member A2
C10ORF95 chromosome 10 open reading frame 95
C1ORF21 chromosome 1 open reading frame 21
C8ORF60 chromosome 8 open reading frame 60
CENPO centromere protein O
CFAP69 cilia and flagella associated protein 69
CHST10 carbohydrate sulfotransferase 10
CORO7 coronin 7
COX6A2 cytochrome c oxidase subunit VIa polypeptide 2
CPED1 cadherin-like and PC-esterase domain containing 1
CRMP1 collapsin response mediator protein 1
CYP26A1 cytochrome P450, family 26, subfamily A, polypeptide 1
DRD1 dopamine receptor D1
DVL1 dishevelled segment polarity protein 1
DYRK3 dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3
ELP6 elongator acetyltransferase complex subunit 6
ERCC6 excision repair cross-complementation group 6
ERO1L ERO1-like (S. cerevisiae)
EXD3 exonuclease 3'-5' domain containing 3
FADS2 fatty acid desaturase 2
FAM120C family with sequence similarity 120C
FAM186A family with sequence similarity 186, member A
FAM46C family with sequence similarity 46, member C
FBXL7 F-box and leucine-rich repeat protein 7
FBXL8 F-box and leucine-rich repeat protein 8
FGL1 fibrinogen-like 1
FLJ21369 uncharacterized protein FLJ21369
FMOD fibromodulin
GEMIN8 gem (nuclear organelle) associated protein 8
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNG13 guanine nucleotide binding protein (G protein), gamma 13
GRM6 glutamate receptor, metabotropic 6
HIST1H3E histone cluster 1, H3e
HOXB2 homeobox B2
HTR1F 5-hydroxytryptamine (serotonin) receptor 1F, G protein-coupled
HYI hydroxypyruvate isomerase (putative)
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IL4R interleukin 4 receptor
INO80D INO80 complex subunit D
INPP5J inositol polyphosphate-5-phosphatase J
IQSEC2 IQ motif and Sec7 domain 2
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KCTD7 potassium channel tetramerization domain containing 7
KRT13 keratin 13, type I
KRT83 keratin 83, type II
LINC00597 long intergenic non-protein coding RNA 597
LRP5L low density lipoprotein receptor-related protein 5-like
LTBP2 latent transforming growth factor beta binding protein 2
MGC2889 uncharacterized protein MGC2889
NDOR1 NADPH dependent diflavin oxidoreductase 1
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NLRX1 NLR family member X1
NPY6R neuropeptide Y receptor Y6 (pseudogene)
PLAC1 placenta-specific 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POMT2 protein-O-mannosyltransferase 2
POPDC3 popeye domain containing 3
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PPT2 palmitoyl-protein thioesterase 2
PROL1 proline rich, lacrimal 1
PRSS53 protease, serine, 53
PTPRM protein tyrosine phosphatase, receptor type, M
RAMP1 receptor (G protein-coupled) activity modifying protein 1
RFNG RFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
RIN2 Ras and Rab interactor 2
RPGR retinitis pigmentosa GTPase regulator
SCGB2A2 secretoglobin, family 2A, member 2
SDC3 syndecan 3
SGK2 serum/glucocorticoid regulated kinase 2
SLC12A9 solute carrier family 12, member 9
SLN sarcolipin
SMR3A submaxillary gland androgen regulated protein 3A
SPAG4 sperm associated antigen 4
SPINK2 serine peptidase inhibitor, Kazal type 2 (acrosin-trypsin inhibitor)
SPINK4 serine peptidase inhibitor, Kazal type 4
SRPX sushi-repeat containing protein, X-linked
STAB2 stabilin 2
TAOK1 TAO kinase 1
TBX19 T-box 19
TCEB3B transcription elongation factor B polypeptide 3B (elongin A2)
TM4SF4 transmembrane 4 L six family member 4
TNS2 tensin 2
TRAIP TRAF interacting protein
UPK2 uroplakin 2
VIPR1 vasoactive intestinal peptide receptor 1
ZBTB44 zinc finger and BTB domain containing 44
ZNF10 zinc finger protein 10
ZNF205 zinc finger protein 205
ZNF280A zinc finger protein 280A
ZNF304 zinc finger protein 304
ZNF767P zinc finger family member 767, pseudogene