suprofen-4005 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the suprofen-4005 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
AAGAB alpha- and gamma-adaptin binding protein
ACSM3 acyl-CoA synthetase medium-chain family member 3
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
ALDOB aldolase B, fructose-bisphosphate
ASIC2 acid sensing (proton gated) ion channel 2
BEND5 BEN domain containing 5
C1ORF61 chromosome 1 open reading frame 61
C21ORF2 chromosome 21 open reading frame 2
C8A complement component 8, alpha polypeptide
CA3 carbonic anhydrase III
CACFD1 calcium channel flower domain containing 1
CALY calcyon neuron-specific vesicular protein
CASP8 caspase 8, apoptosis-related cysteine peptidase
CCDC30 coiled-coil domain containing 30
CD226 CD226 molecule
CD4 CD4 molecule
CDC14B cell division cycle 14B
CDK13 cyclin-dependent kinase 13
CDK20 cyclin-dependent kinase 20
CES3 carboxylesterase 3
COBL cordon-bleu WH2 repeat protein
COMMD4 COMM domain containing 4
CSF1R colony stimulating factor 1 receptor
CSN3 casein kappa
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DBP D site of albumin promoter (albumin D-box) binding protein
DOCK10 dedicator of cytokinesis 10
DPY19L1P1 DPY19L1 pseudogene 1
EGR1 early growth response 1
ELOVL2 ELOVL fatty acid elongase 2
ENPP2 ectonucleotide pyrophosphatase/phosphodiesterase 2
FCER1G Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
FGFR1 fibroblast growth factor receptor 1
FOXF1 forkhead box F1
GAL3ST4 galactose-3-O-sulfotransferase 4
GATM glycine amidinotransferase (L-arginine:glycine amidinotransferase)
GUCY2F guanylate cyclase 2F, retinal
HEMK1 HemK methyltransferase family member 1
HIPK3 homeodomain interacting protein kinase 3
HIST1H4D histone cluster 1, H4d
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IL12A interleukin 12A
IL1RN interleukin 1 receptor antagonist
IL22 interleukin 22
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNJ5 potassium channel, inwardly rectifying subfamily J, member 5
KRT9 keratin 9, type I
LAT2 linker for activation of T cells family, member 2
LEFTY2 left-right determination factor 2
LIPG lipase, endothelial
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
MAP2K5 mitogen-activated protein kinase kinase 5
MARS methionyl-tRNA synthetase
MATN1 matrilin 1, cartilage matrix protein
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
NDUFB7 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa
OAZ3 ornithine decarboxylase antizyme 3
OLFML2B olfactomedin-like 2B
OSBPL10 oxysterol binding protein-like 10
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PDE2A phosphodiesterase 2A, cGMP-stimulated
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLXDC1 plexin domain containing 1
PRKCE protein kinase C, epsilon
PROSC proline synthetase co-transcribed homolog (bacterial)
PSD4 pleckstrin and Sec7 domain containing 4
PTPN21 protein tyrosine phosphatase, non-receptor type 21
RABGAP1 RAB GTPase activating protein 1
RFX2 regulatory factor X, 2 (influences HLA class II expression)
SEC14L5 SEC14-like 5 (S. cerevisiae)
SIGLEC6 sialic acid binding Ig-like lectin 6
SKAP1 src kinase associated phosphoprotein 1
SP110 SP110 nuclear body protein
SPOCK3 sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3
STK24 serine/threonine kinase 24
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
TAC3 tachykinin 3
TBXA2R thromboxane A2 receptor
TFCP2L1 transcription factor CP2-like 1
THRB thyroid hormone receptor, beta
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TNFRSF9 tumor necrosis factor receptor superfamily, member 9
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TTC30A tetratricopeptide repeat domain 30A
TUBA3C tubulin, alpha 3c
VGF VGF nerve growth factor inducible
WNK1 WNK lysine deficient protein kinase 1
XYLB xylulokinase homolog (H. influenzae)
ZCCHC11 zinc finger, CCHC domain containing 11
ZFPL1 zinc finger protein-like 1
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF500 zinc finger protein 500
ZNF573 zinc finger protein 573
ZZEF1 zinc finger, ZZ-type with EF-hand domain 1

decreased expression

Symbol Name
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3
ADGRF1 adhesion G protein-coupled receptor F1
AGMAT agmatine ureohydrolase (agmatinase)
ALOX15B arachidonate 15-lipoxygenase, type B
ANXA10 annexin A10
APOC4 apolipoprotein C-IV
ARMCX4 armadillo repeat containing, X-linked 4
AXIN1 axin 1
B9D2 B9 protein domain 2
C14ORF105 chromosome 14 open reading frame 105
C1QTNF1 C1q and tumor necrosis factor related protein 1
C1R complement component 1, r subcomponent
C5 complement component 5
CBX8 chromobox homolog 8
CCDC94 coiled-coil domain containing 94
CNR2 cannabinoid receptor 2 (macrophage)
CNTLN centlein, centrosomal protein
COL9A3 collagen, type IX, alpha 3
CREB5 cAMP responsive element binding protein 5
DCAF13 DDB1 and CUL4 associated factor 13
DDN dendrin
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DLL3 delta-like 3 (Drosophila)
DNAH17 dynein, axonemal, heavy chain 17
EPN1 epsin 1
EXOC6B exocyst complex component 6B
FOXC1 forkhead box C1
FSTL3 follistatin-like 3 (secreted glycoprotein)
GJA9 gap junction protein, alpha 9, 59kDa
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2AJ histone cluster 1, H2aj
HIST1H3B histone cluster 1, H3b
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
HSPA1L heat shock 70kDa protein 1-like
HSPB6 heat shock protein, alpha-crystallin-related, B6
IGLL1 immunoglobulin lambda-like polypeptide 1
IPO8 importin 8
IQSEC2 IQ motif and Sec7 domain 2
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
KIAA0754 KIAA0754
KIRREL kin of IRRE like (Drosophila)
LIME1 Lck interacting transmembrane adaptor 1
LINC00260 long intergenic non-protein coding RNA 260
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAST3 microtubule associated serine/threonine kinase 3
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MN1 meningioma (disrupted in balanced translocation) 1
MOB3B MOB kinase activator 3B
MPST mercaptopyruvate sulfurtransferase
MTSS1L metastasis suppressor 1-like
MXD3 MAX dimerization protein 3
OPLAH 5-oxoprolinase (ATP-hydrolysing)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PALMD palmdelphin
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLBD1 phospholipase B domain containing 1
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
POLL polymerase (DNA directed), lambda
POMT2 protein-O-mannosyltransferase 2
PRPH peripherin
PRSS53 protease, serine, 53
QSER1 glutamine and serine rich 1
RFPL1S RFPL1 antisense RNA 1
RGCC regulator of cell cycle
RHOBTB2 Rho-related BTB domain containing 2
RIN1 Ras and Rab interactor 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SAMD9 sterile alpha motif domain containing 9
SCUBE3 signal peptide, CUB domain, EGF-like 3
SELL selectin L
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SH3D21 SH3 domain containing 21
SLAMF7 SLAM family member 7
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC9A2 solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SSTR4 somatostatin receptor 4
SUGCT succinyl-CoA:glutarate-CoA transferase
TMEM8B transmembrane protein 8B
TSNAXIP1 translin-associated factor X interacting protein 1
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
ZCWPW1 zinc finger, CW type with PWWP domain 1
ZFHX3 zinc finger homeobox 3
ZFP30 ZFP30 zinc finger protein
ZNF268 zinc finger protein 268
ZNF510 zinc finger protein 510
ZNF667 zinc finger protein 667