supraoptic nucleus Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description A sharply defined nucleus of nerve cells in the anterior hypothalamic region, immediately above the lateral part of the optic chiasm; many of its cells are neurosecretory in function, secreting vasopressin, which is carried to the neurohypophysis (posterior pituitary) by the fibers of the supraopticohypophysial tract; other cells are osmoreceptors, which respond to increased osmotic pressure to signal the release of vasopressin by the neurohypophysis. (BRENDA Tissue and Enzyme Source Ontology, BTO_0002697)
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Genes

194 proteins co-occuring with the tissue supraoptic nucleus in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
FOS FBJ murine osteosarcoma viral oncogene homolog 2.70717
AVP arginine vasopressin 2.65147
OXT oxytocin/neurophysin I prepropeptide 2.28596
CRH corticotropin releasing hormone 1.97201
NPS neuropeptide S 1.67456
POMC proopiomelanocortin 1.5982
GAL galanin/GMAP prepropeptide 1.55455
CCK cholecystokinin 1.51237
TH tyrosine hydroxylase 1.49914
OXTR oxytocin receptor 1.45518
PDYN prodynorphin 1.42045
SIM1 single-minded family bHLH transcription factor 1 1.24967
NPY neuropeptide Y 1.22291
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 1.15096
ADCYAP1 adenylate cyclase activating polypeptide 1 (pituitary) 1.14653
FOSB FBJ murine osteosarcoma viral oncogene homolog B 1.11331
PRLH prolactin releasing hormone 1.08766
UCN urocortin 1.08501
RXFP3 relaxin/insulin-like family peptide receptor 3 1.06162
RLN3 relaxin 3 1.05721
RANBP3 RAN binding protein 3 1.05369
ESR2 estrogen receptor 2 (ER beta) 1.04664
HDLBP high density lipoprotein binding protein 0.988466
NPPA natriuretic peptide A 0.977182
NUCB2 nucleobindin 2 0.963767
SST somatostatin 0.962903
GNRH1 gonadotropin-releasing hormone 1 (luteinizing-releasing hormone) 0.944796
ADM2 adrenomedullin 2 0.940066
ESR1 estrogen receptor 1 0.912226
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 0.90285
TACR3 tachykinin receptor 3 0.901147
NTS neurotensin 0.857995
CRHR1 corticotropin releasing hormone receptor 1 0.850425
POU3F2 POU class 3 homeobox 2 0.838252
TRH thyrotropin-releasing hormone 0.823594
PRL prolactin 0.818576
LEPR leptin receptor 0.80271
VGF VGF nerve growth factor inducible 0.801876
GRIN2D glutamate receptor, ionotropic, N-methyl D-aspartate 2D 0.793126
REN renin 0.78522
SCG5 secretogranin V 0.77193
GALR1 galanin receptor 1 0.770685
AGRP agouti related neuropeptide 0.760328
NPTX2 neuronal pentraxin II 0.755364
PENK proenkephalin 0.748753
CPE carboxypeptidase E 0.748753
HK1 hexokinase 1 0.746689
NPFF neuropeptide FF-amide peptide precursor 0.740503
TAC1 tachykinin, precursor 1 0.735971
CARTPT CART prepropeptide 0.722809
CORT cortistatin 0.722398
PALMD palmdelphin 0.719934
VIP vasoactive intestinal peptide 0.71542
GALR3 galanin receptor 3 0.704355
TRPV2 transient receptor potential cation channel, subfamily V, member 2 0.699444
NMU neuromedin U 0.695354
GALR2 galanin receptor 2 0.691676
FOSL1 FOS-like antigen 1 0.691676
KARS lysyl-tRNA synthetase 0.679433
RLN1 relaxin 1 0.674135
CALB1 calbindin 1, 28kDa 0.661116
AVPR1B arginine vasopressin receptor 1B 0.660304
OXR1 oxidation resistance 1 0.65543
GAD2 glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) 0.654212
GRIN2C glutamate receptor, ionotropic, N-methyl D-aspartate 2C 0.63719
HCRT hypocretin (orexin) neuropeptide precursor 0.636785
SCG2 secretogranin II 0.631123
ADM adrenomedullin 0.625061
RPL24 ribosomal protein L24 0.624658
GABBR1 gamma-aminobutyric acid (GABA) B receptor, 1 0.618603
JUN jun proto-oncogene 0.613764
P2RX2 purinergic receptor P2X, ligand gated ion channel, 2 0.605306
RPS27L ribosomal protein S27-like 0.604502
LEP leptin 0.588431
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 0.587228
APLNR apelin receptor 0.581218
DECR1 2,4-dienoyl CoA reductase 1, mitochondrial 0.567227
CRTC3 CREB regulated transcription coactivator 3 0.56284
MEA1 male-enhanced antigen 1 0.556467
PRLR prolactin receptor 0.545739
INS insulin 0.544946
SLC17A6 solute carrier family 17 (vesicular glutamate transporter), member 6 0.53346
CREB1 cAMP responsive element binding protein 1 0.52635
ARNT2 aryl-hydrocarbon receptor nuclear translocator 2 0.524377
PNOC prepronociceptin 0.511384
GALP galanin-like peptide 0.509027
CNTF ciliary neurotrophic factor 0.508242
SYT5 synaptotagmin V 0.506279
TRPV1 transient receptor potential cation channel, subfamily V, member 1 0.50471
CNR1 cannabinoid receptor 1 (brain) 0.501574
GRIN2B glutamate receptor, ionotropic, N-methyl D-aspartate 2B 0.496092
CHAT choline O-acetyltransferase 0.489447
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8) 0.488276
MANF mesencephalic astrocyte-derived neurotrophic factor 0.478923
RICTOR RPTOR independent companion of MTOR, complex 2 0.478145
RPS27 ribosomal protein S27 0.476979
C2ORF40 chromosome 2 open reading frame 40 0.472704
NPW neuropeptide W 0.466885
CALB2 calbindin 2 0.463013
AVPR1A arginine vasopressin receptor 1A 0.462626
PTPRZ1 protein tyrosine phosphatase, receptor-type, Z polypeptide 1 0.461465
OPRL1 opiate receptor-like 1 0.456828
NMUR2 neuromedin U receptor 2 0.452969
ACE angiotensin I converting enzyme 0.449116
ACHE acetylcholinesterase (Yt blood group) 0.448731
PALM paralemmin 0.448346
AZIN1 antizyme inhibitor 1 0.447576
MC4R melanocortin 4 receptor 0.437972
AQP4 aquaporin 4 0.435672
MAOA monoamine oxidase A 0.433374
TECTA tectorin alpha 0.428401
TRIM37 tripartite motif containing 37 0.414673
RESP18 regulated endocrine-specific protein 18 0.414293
NOS1 nitric oxide synthase 1 (neuronal) 0.409351
OPN5 opsin 5 0.409351
CAPRIN2 caprin family member 2 0.407073
CYP11B2 cytochrome P450, family 11, subfamily B, polypeptide 2 0.405555
NR3C2 nuclear receptor subfamily 3, group C, member 2 0.398357
CPA6 carboxypeptidase A6 0.397979
SLC1A2 solute carrier family 1 (glial high affinity glutamate transporter), member 2 0.397979
NRD1 nardilysin (N-arginine dibasic convertase) 0.394197
GCG glucagon 0.393442
GRIN2A glutamate receptor, ionotropic, N-methyl D-aspartate 2A 0.38439
TFF2 trefoil factor 2 0.379875
PRLHR prolactin releasing hormone receptor 0.379123
ADRA2C adrenoceptor alpha 2C 0.374618
ADAMTS2 ADAM metallopeptidase with thrombospondin type 1 motif, 2 0.373118
RXFP1 relaxin/insulin-like family peptide receptor 1 0.368998
PTGER1 prostaglandin E receptor 1 (subtype EP1), 42kDa 0.368998
CNGA1 cyclic nucleotide gated channel alpha 1 0.367129
RXFP4 relaxin/insulin-like family peptide receptor 4 0.366007
SCNN1B sodium channel, non voltage gated 1 beta subunit 0.364886
KISS1R KISS1 receptor 0.36302
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.358546
NGF nerve growth factor (beta polypeptide) 0.358174
PLXNC1 plexin C1 0.354084
TFF1 trefoil factor 1 0.352969
CREM cAMP responsive element modulator 0.350372
KIF1BP KIF1 binding protein 0.347778
STX8 syntaxin 8 0.347038
OPRM1 opioid receptor, mu 1 0.345188
NPPC natriuretic peptide C 0.342233
RORA RAR-related orphan receptor A 0.334865
GPER1 G protein-coupled estrogen receptor 1 0.333028
PAPSS2 3'-phosphoadenosine 5'-phosphosulfate synthase 2 0.33046
TFF3 trefoil factor 3 (intestinal) 0.327164
TRPV4 transient receptor potential cation channel, subfamily V, member 4 0.32497
NMS neuromedin S 0.324239
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.32132
IL1B interleukin 1, beta 0.32132
NPY5R neuropeptide Y receptor Y5 0.31877
NPPB natriuretic peptide B 0.316951
CPB1 carboxypeptidase B1 (tissue) 0.316588
ADCYAP1R1 adenylate cyclase activating polypeptide 1 (pituitary) receptor type I 0.315498
PCSK1 proprotein convertase subtilisin/kexin type 1 0.314046
GHRH growth hormone releasing hormone 0.307889
CHRFAM7A CHRNA7 (cholinergic receptor, nicotinic, alpha 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion 0.307167
ACPT acid phosphatase, testicular 0.304279
CREB3L1 cAMP responsive element binding protein 3-like 1 0.301758
PCSK1N proprotein convertase subtilisin/kexin type 1 inhibitor 0.298524
GRM7 glutamate receptor, metabotropic 7 0.291722
GAD1 glutamate decarboxylase 1 (brain, 67kDa) 0.285671
CTHRC1 collagen triple helix repeat containing 1 0.284607
BDNF brain-derived neurotrophic factor 0.283545
ATP6AP2 ATPase, H+ transporting, lysosomal accessory protein 2 0.28213
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 0.278955
SRR serine racemase 0.274394
GLUL glutamate-ammonia ligase 0.273346
CALCA calcitonin-related polypeptide alpha 0.272649
ATF2 activating transcription factor 2 0.271952
PAM peptidylglycine alpha-amidating monooxygenase 0.269521
HCN3 hyperpolarization activated cyclic nucleotide gated potassium channel 3 0.265725
LEMD3 LEM domain containing 3 0.252919
HTR5A 5-hydroxytryptamine (serotonin) receptor 5A, G protein-coupled 0.251606
RXRG retinoid X receptor, gamma 0.247079
GRM4 glutamate receptor, metabotropic 4 0.242054
KCNJ9 potassium channel, inwardly rectifying subfamily J, member 9 0.240826
DRD4 dopamine receptor D4 0.234878
SERPINA6 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6 0.234016
EDN3 endothelin 3 0.232039
CHGB chromogranin B 0.227186
KNG1 kininogen 1 0.222938
PRSS50 protease, serine, 50 0.222699
GFAP glial fibrillary acidic protein 0.221755
PNMT phenylethanolamine N-methyltransferase 0.221291
P2RX4 purinergic receptor P2X, ligand gated ion channel, 4 0.220831
POU3F3 POU class 3 homeobox 3 0.220378
YME1L1 YME1-like 1 ATPase 0.218398
GRIA1 glutamate receptor, ionotropic, AMPA 1 0.217974
GPHN gephyrin 0.216325
ATRN attractin 0.215534
YWHAG tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma 0.214576
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.212936
GRP gastrin-releasing peptide 0.212586