supportive connective tissue Gene Set

Dataset TISSUES Text-mining Tissue Protein Expression Evidence Scores
Category structural or functional annotations
Type tissue
Description Classified as supportive connective tissue are bone, osseous tissue, that makes up virtually the entire skeleton in adult vertebrates and cartilage makes up virtually the entire skeleton in chondrichthyes. In most other vertebrates, it is found primarily in joints, where it provides cushioning. (BRENDA Tissue and Enzyme Source Ontology, BTO_0004568)
Similar Terms
Downloads & Tools

Genes

225 proteins co-occuring with the tissue supportive connective tissue in abstracts of biomedical publications from the TISSUES Text-mining Tissue Protein Expression Evidence Scores dataset.

Symbol Name Standardized Value
TNF tumor necrosis factor 2.21562
IFNA1 interferon, alpha 1 1.46449
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.29175
AHCY adenosylhomocysteinase 1.27919
TOR3A torsin family 3, member A 1.2452
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1 1.14697
IFNA4 interferon, alpha 4 1.13058
LTA lymphotoxin alpha 1.11464
RNASEL ribonuclease L (2',5'-oligoisoadenylate synthetase-dependent) 1.08369
LARP1B La ribonucleoprotein domain family, member 1B 1.06559
TIAF1 TGFB1-induced anti-apoptotic factor 1 1.05061
IFNB1 interferon, beta 1, fibroblast 1.04225
CD3D CD3d molecule, delta (CD3-TCR complex) 1.04225
BECN1 beclin 1, autophagy related 1.04225
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.00719
KRI1 KRI1 homolog (S. cerevisiae) 0.973716
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) 0.96809
PLEKHF2 pleckstrin homology domain containing, family F (with FYVE domain) member 2 0.95988
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.943935
EIF2S1 eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa 0.905831
CDHR5 cadherin-related family member 5 0.90285
IRF1 interferon regulatory factor 1 0.865577
NGF nerve growth factor (beta polypeptide) 0.837414
MAK16 MAK16 homolog (S. cerevisiae) 0.834061
IL6 interleukin 6 0.82736
IL1B interleukin 1, beta 0.817322
PGLYRP1 peptidoglycan recognition protein 1 0.815233
AHCYL2 adenosylhomocysteinase-like 2 0.804796
IFNAR2 interferon (alpha, beta and omega) receptor 2 0.78231
NOS2 nitric oxide synthase 2, inducible 0.781894
JUN jun proto-oncogene 0.774004
CASP8 caspase 8, apoptosis-related cysteine peptidase 0.769027
MMD monocyte to macrophage differentiation-associated 0.764882
MAP3K5 mitogen-activated protein kinase kinase kinase 5 0.761155
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 0.75495
IFNAR1 interferon (alpha, beta and omega) receptor 1 0.752884
CASP3 caspase 3, apoptosis-related cysteine peptidase 0.728563
PGAM5 phosphoglycerate mutase family member 5 0.725274
AHCYL1 adenosylhomocysteinase-like 1 0.719934
IFNA2 interferon, alpha 2 0.70845
TRADD TNFRSF1A-associated via death domain 0.707631
IFNA21 interferon, alpha 21 0.703945
DHX58 DEXH (Asp-Glu-X-His) box polypeptide 58 0.699035
CTSL cathepsin L 0.698216
HSPA4 heat shock 70kDa protein 4 0.68188
IFNA17 interferon, alpha 17 0.680656
TK1 thymidine kinase 1, soluble 0.670064
SNIP1 Smad nuclear interacting protein 1 0.668843
CRYAB crystallin, alpha B 0.661116
TGFB1 transforming growth factor, beta 1 0.659897
DNASE1 deoxyribonuclease I 0.648127
GLRA1 glycine receptor, alpha 1 0.63638
GIN1 gypsy retrotransposon integrase 1 0.614571
PPID peptidylprolyl isomerase D 0.614571
APBB2 amyloid beta (A4) precursor protein-binding, family B, member 2 0.613361
ALB albumin 0.610541
PARP1 poly (ADP-ribose) polymerase 1 0.606514
GABARAP GABA(A) receptor-associated protein 0.598469
RIPK3 receptor-interacting serine-threonine kinase 3 0.596862
BAX BCL2-associated X protein 0.590036
AXIN1 axin 1 0.587228
MAPK9 mitogen-activated protein kinase 9 0.585224
OPN1LW opsin 1 (cone pigments), long-wave-sensitive 0.58322
PIBF1 progesterone immunomodulatory binding factor 1 0.58322
OPN1MW2 opsin 1 (cone pigments), medium-wave-sensitive 2 0.58242
NLRP2 NLR family, pyrin domain containing 2 0.575616
OPN1MW opsin 1 (cone pigments), medium-wave-sensitive 0.572018
MTBP MDM2 binding protein 0.558457
RCN1 reticulocalbin 1, EF-hand calcium binding domain 0.558059
FN1 fibronectin 1 0.557263
TSPO translocator protein (18kDa) 0.556865
LCN1 lipocalin 1 0.556467
IRF2 interferon regulatory factor 2 0.549709
CISD1 CDGSH iron sulfur domain 1 0.547326
CDH13 cadherin 13 0.546136
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.533856
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.529508
TFAP4 transcription factor AP-4 (activating enhancer binding protein 4) 0.527139
AP1M2 adaptor-related protein complex 1, mu 2 subunit 0.52635
IFI35 interferon-induced protein 35 0.520041
IL1A interleukin 1, alpha 0.517678
SOD2 superoxide dismutase 2, mitochondrial 0.516891
ODC1 ornithine decarboxylase 1 0.510992
AP2M1 adaptor-related protein complex 2, mu 1 subunit 0.510992
ZHX2 zinc fingers and homeoboxes 2 0.505102
USP26 ubiquitin specific peptidase 26 0.499223
IGHV3-30 immunoglobulin heavy variable 3-30 0.492963
TP53 tumor protein p53 0.490619
IFNA8 interferon, alpha 8 0.486326
CAT catalase 0.482817
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1 0.480091
OR2AG1 olfactory receptor, family 2, subfamily AG, member 1 (gene/pseudogene) 0.475423
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled 0.471927
EIF4B eukaryotic translation initiation factor 4B 0.469211
KAT5 K(lysine) acetyltransferase 5 0.468436
FKBP4 FK506 binding protein 4, 59kDa 0.466498
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.466111
DPEP1 dipeptidase 1 (renal) 0.461852
ANXA5 annexin A5 0.456442
IL2 interleukin 2 0.453355
MRVI1 murine retrovirus integration site 1 homolog 0.438739
MLKL mixed lineage kinase domain-like 0.438739
RNASEH2A ribonuclease H2, subunit A 0.437205
HLA-B major histocompatibility complex, class I, B 0.435672
MMP9 matrix metallopeptidase 9 0.434523
NLRP6 NLR family, pyrin domain containing 6 0.433374
FOS FBJ murine osteosarcoma viral oncogene homolog 0.433374
PEBP4 phosphatidylethanolamine-binding protein 4 0.432991
GRAP GRB2-related adaptor protein 0.429165
CSF2 colony stimulating factor 2 (granulocyte-macrophage) 0.419242
BCL2L1 BCL2-like 1 0.418861
LPA lipoprotein, Lp(a) 0.417337
FASLG Fas ligand (TNF superfamily, member 6) 0.415053
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1 0.408592
PLEKHG5 pleckstrin homology domain containing, family G (with RhoGef domain) member 5 0.408592
SLAMF7 SLAM family member 7 0.40366
GNAI3 guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3 0.397979
SELPLG selectin P ligand 0.385143
JAK1 Janus kinase 1 0.384766
LMO3 LIM domain only 3 (rhombotin-like 2) 0.384766
APBB1 amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) 0.384013
MAPK14 mitogen-activated protein kinase 14 0.384013
WWOX WW domain containing oxidoreductase 0.383637
IFNG interferon, gamma 0.377621
PIGG phosphatidylinositol glycan anchor biosynthesis, class G 0.376119
TOP1 topoisomerase (DNA) I 0.374243
SRC SRC proto-oncogene, non-receptor tyrosine kinase 0.369747
CCL1 chemokine (C-C motif) ligand 1 0.369747
ADK adenosine kinase 0.367876
CASP9 caspase 9, apoptosis-related cysteine peptidase 0.367876
LPO lactoperoxidase 0.365633
CELA2A chymotrypsin-like elastase family, member 2A 0.36302
CTSB cathepsin B 0.361901
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.360782
ACD adrenocortical dysplasia homolog (mouse) 0.359292
FAM132A family with sequence similarity 132, member A 0.355942
EIF5 eukaryotic translation initiation factor 5 0.352598
ATG5 autophagy related 5 0.350743
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b 0.350372
INS insulin 0.344449
TNNT3 troponin T type 3 (skeletal, fast) 0.344079
EFNA4 ephrin-A4 0.342602
EPHA8 EPH receptor A8 0.339282
NLRP3 NLR family, pyrin domain containing 3 0.339282
GUSB glucuronidase, beta 0.335968
NCOA2 nuclear receptor coactivator 2 0.335968
PIKFYVE phosphoinositide kinase, FYVE finger containing 0.334865
MNT MAX network transcriptional repressor 0.334498
BMP3 bone morphogenetic protein 3 0.333396
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae) 0.32205
MGAM maltase-glucoamylase 0.320591
PTPRM protein tyrosine phosphatase, receptor type, M 0.309697
CLIC4 chloride intracellular channel 4 0.305722
RGPD3 RANBP2-like and GRIP domain containing 3 0.305722
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 0.302118
NDUFA13 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13 0.29673
RGS19 regulator of G-protein signaling 19 0.292793
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled 0.291008
PKM pyruvate kinase, muscle 0.289226
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2 0.287092
NGFR nerve growth factor receptor 0.285671
ACADM acyl-CoA dehydrogenase, C-4 to C-12 straight chain 0.285671
ATF2 activating transcription factor 2 0.281776
CXCL8 chemokine (C-X-C motif) ligand 8 0.28107
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7 0.277197
FGF2 fibroblast growth factor 2 (basic) 0.275094
PDIA6 protein disulfide isomerase family A, member 6 0.274744
BRD2 bromodomain containing 2 0.274394
GJA1 gap junction protein, alpha 1, 43kDa 0.271952
TREM1 triggering receptor expressed on myeloid cells 1 0.270909
GABRD gamma-aminobutyric acid (GABA) A receptor, delta 0.270214
HMOX1 heme oxygenase 1 0.270214
ENGASE endo-beta-N-acetylglucosaminidase 0.269174
PLA2G1B phospholipase A2, group IB (pancreas) 0.268137
PDZD2 PDZ domain containing 2 0.266413
TUBB tubulin, beta class I 0.265038
PANX1 pannexin 1 0.264011
IL17RA interleukin 17 receptor A 0.261624
AMELY amelogenin, Y-linked 0.261284
IFNGR1 interferon gamma receptor 1 0.255567
TBPL1 TBP-like 1 0.254239
AMELX amelogenin, X-linked 0.253578
EEA1 early endosome antigen 1 0.253578
TMOD1 tropomodulin 1 0.252919
STAT2 signal transducer and activator of transcription 2, 113kDa 0.25259
SLC15A4 solute carrier family 15 (oligopeptide transporter), member 4 0.252261
CERK ceramide kinase 0.252261
LECT2 leukocyte cell-derived chemotaxin 2 0.249653
IFT122 intraflagellar transport 122 0.246124
BCL2 B-cell CLL/lymphoma 2 0.24486
EBF1 early B-cell factor 1 0.244232
PRSS50 protease, serine, 50 0.242983
DDX5 DEAD (Asp-Glu-Ala-Asp) box helicase 5 0.242363
PANX2 pannexin 2 0.240826
DNAH8 dynein, axonemal, heavy chain 8 0.24052
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 0.239913
GPX4 glutathione peroxidase 4 0.238706
LMO1 LIM domain only 1 (rhombotin 1) 0.236627
XPR1 xenotropic and polytropic retrovirus receptor 1 0.23459
SOCS5 suppressor of cytokine signaling 5 0.234302
CD40LG CD40 ligand 0.233446
C1QB complement component 1, q subcomponent, B chain 0.232881
BMF Bcl2 modifying factor 0.229568
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 0.227186
RENBP renin binding protein 0.226926
FECH ferrochelatase 0.226926
CALCA calcitonin-related polypeptide alpha 0.226667
NLRP1 NLR family, pyrin domain containing 1 0.226411
HMBS hydroxymethylbilane synthase 0.225395
CAST calpastatin 0.224645
IL6R interleukin 6 receptor 0.222699
BEAN1 brain expressed, associated with NEDD4, 1 0.22246
GYS1 glycogen synthase 1 (muscle) 0.22246
TXN thioredoxin 0.22246
MAP2K3 mitogen-activated protein kinase kinase 3 0.221989
TLR4 toll-like receptor 4 0.221989
LGR5 leucine-rich repeat containing G protein-coupled receptor 5 0.221291
ALPPL2 alkaline phosphatase, placental-like 2 0.220604
ALPL alkaline phosphatase, liver/bone/kidney 0.220152
ALPP alkaline phosphatase, placental 0.219707
DUOXA1 dual oxidase maturation factor 1 0.216528
GSTM1 glutathione S-transferase mu 1 0.214765
GFER growth factor, augmenter of liver regeneration 0.213291
ADAM19 ADAM metallopeptidase domain 19 0.212761
TPR translocated promoter region, nuclear basket protein 0.212586