sumo-targeted ubiquitin ligase complex Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A nuclear ubiquitin ligase complex that specifically targets SUMOylated proteins; the complex is formed of homodimers or heterodimers of RNF4 family ubiquitin ligases and is conserved in eukaryotes. (Gene Ontology, GO_0033768)
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42 proteins co-occuring with the sumo-targeted ubiquitin ligase complex cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
RNF4 ring finger protein 4 2.74871
NFATC2IP nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 interacting protein 1.58507
SUMO3 small ubiquitin-like modifier 3 1.53557
RNF111 ring finger protein 111 1.52428
SUMO2 small ubiquitin-like modifier 2 1.51186
RNF165 ring finger protein 165 1.35704
C18ORF25 chromosome 18 open reading frame 25 1.27877
TMEM189 transmembrane protein 189 1.26286
UBE2W ubiquitin-conjugating enzyme E2W (putative) 1.21325
TMEM189-UBE2V1 TMEM189-UBE2V1 readthrough 1.15774
SENP6 SUMO1/sentrin specific peptidase 6 0.855717
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.778212
CBX4 chromobox homolog 4 0.771363
MUS81 MUS81 structure-specific endonuclease subunit 0.762252
RAD18 RAD18 E3 ubiquitin protein ligase 0.748641
NSMCE2 non-SMC element 2, MMS21 homolog (S. cerevisiae) 0.740064
BTAF1 BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa 0.73018
TDP1 tyrosyl-DNA phosphodiesterase 1 0.675065
PIAS2 protein inhibitor of activated STAT, 2 0.658619
PIAS4 protein inhibitor of activated STAT, 4 0.594332
PARK2 parkin RBR E3 ubiquitin protein ligase 0.579251
SENP1 SUMO1/sentrin specific peptidase 1 0.57008
CENPH centromere protein H 0.5597
PIAS1 protein inhibitor of activated STAT, 1 0.553905
UBE2I ubiquitin-conjugating enzyme E2I 0.545648
NPLOC4 nuclear protein localization 4 homolog (S. cerevisiae) 0.534951
RAD52 RAD52 homolog (S. cerevisiae) 0.525113
HSPA1B heat shock 70kDa protein 1B 0.503912
UBE2H ubiquitin-conjugating enzyme E2H 0.495395
REV3L REV3-like, polymerase (DNA directed), zeta, catalytic subunit 0.476831
SMARCA2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2 0.465598
ISG15 ISG15 ubiquitin-like modifier 0.452427
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 0.415728
UBE2N ubiquitin-conjugating enzyme E2N 0.415337
HSPA1A heat shock 70kDa protein 1A 0.375434
RAD21 RAD21 homolog (S. pombe) 0.344935
XPC xeroderma pigmentosum, complementation group C 0.332095
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.327956
AXIN1 axin 1 0.275936
CLIP1 CAP-GLY domain containing linker protein 1 0.267139
CFTR cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7) 0.234891
PML promyelocytic leukemia 0.160254