sulpiride-4566 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the sulpiride-4566 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACRV1 acrosomal vesicle protein 1
ACSM5 acyl-CoA synthetase medium-chain family member 5
ADAP2 ArfGAP with dual PH domains 2
ALPK1 alpha-kinase 1
ARC activity-regulated cytoskeleton-associated protein
ARHGAP22 Rho GTPase activating protein 22
ARTN artemin
BCAM basal cell adhesion molecule (Lutheran blood group)
BTG2 BTG family, member 2
C14ORF105 chromosome 14 open reading frame 105
C1ORF21 chromosome 1 open reading frame 21
C8B complement component 8, beta polypeptide
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CACNG1 calcium channel, voltage-dependent, gamma subunit 1
CAMTA1 calmodulin binding transcription activator 1
CASP1 caspase 1, apoptosis-related cysteine peptidase
CD6 CD6 molecule
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CDKL1 cyclin-dependent kinase-like 1 (CDC2-related kinase)
CEACAM7 carcinoembryonic antigen-related cell adhesion molecule 7
CNTNAP2 contactin associated protein-like 2
COL17A1 collagen, type XVII, alpha 1
CPT1A carnitine palmitoyltransferase 1A (liver)
CRH corticotropin releasing hormone
CXORF21 chromosome X open reading frame 21
CYP4F11 cytochrome P450, family 4, subfamily F, polypeptide 11
CYSLTR1 cysteinyl leukotriene receptor 1
DCLK2 doublecortin-like kinase 2
DMWD dystrophia myotonica, WD repeat containing
DOHH deoxyhypusine hydroxylase/monooxygenase
DOK4 docking protein 4
EGLN3 egl-9 family hypoxia-inducible factor 3
EXOSC1 exosome component 1
FAM174B family with sequence similarity 174, member B
FGL1 fibrinogen-like 1
FLT4 fms-related tyrosine kinase 4
FRMPD1 FERM and PDZ domain containing 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GPM6B glycoprotein M6B
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IL37 interleukin 37
ING2 inhibitor of growth family, member 2
ITIH3 inter-alpha-trypsin inhibitor heavy chain 3
JAK3 Janus kinase 3
KCNS1 potassium voltage-gated channel, modifier subfamily S, member 1
KLHL22 kelch-like family member 22
KYNU kynureninase
LBP lipopolysaccharide binding protein
LMOD1 leiomodin 1 (smooth muscle)
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK4 mitogen-activated protein kinase 4
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MRC2 mannose receptor, C type 2
MYRIP myosin VIIA and Rab interacting protein
NEUROD1 neuronal differentiation 1
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein
NRP2 neuropilin 2
NTF3 neurotrophin 3
OMD osteomodulin
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PAX1 paired box 1
PAX8 paired box 8
PDE4D phosphodiesterase 4D, cAMP-specific
PDE4DIP phosphodiesterase 4D interacting protein
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLEKHS1 pleckstrin homology domain containing, family S member 1
POLDIP3 polymerase (DNA-directed), delta interacting protein 3
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRB1 proline-rich protein BstNI subfamily 1
PSG11 pregnancy specific beta-1-glycoprotein 11
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PTPN1 protein tyrosine phosphatase, non-receptor type 1
RBBP9 retinoblastoma binding protein 9
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RGS9 regulator of G-protein signaling 9
RPL10L ribosomal protein L10-like
RYR2 ryanodine receptor 2 (cardiac)
SATB2 SATB homeobox 2
SEMG2 semenogelin II
SLAMF7 SLAM family member 7
SORBS2 sorbin and SH3 domain containing 2
SPEF1 sperm flagellar 1
SPON1 spondin 1, extracellular matrix protein
SPRR1A small proline-rich protein 1A
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SUSD5 sushi domain containing 5
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
SYT12 synaptotagmin XII
TBX6 T-box 6
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
TLR4 toll-like receptor 4
TTC38 tetratricopeptide repeat domain 38
UNC13A unc-13 homolog A (C. elegans)
UPK2 uroplakin 2
UPK3B uroplakin 3B
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)

decreased expression

Symbol Name
ACTR6 ARP6 actin-related protein 6 homolog (yeast)
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADNP activity-dependent neuroprotector homeobox
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
AGPAT5 1-acylglycerol-3-phosphate O-acyltransferase 5
AIDA axin interactor, dorsalization associated
ANKFY1 ankyrin repeat and FYVE domain containing 1
ARID4A AT rich interactive domain 4A (RBP1-like)
ATF1 activating transcription factor 1
AUH AU RNA binding protein/enoyl-CoA hydratase
BAG2 BCL2-associated athanogene 2
BOLA1 bolA family member 1
C4ORF19 chromosome 4 open reading frame 19
CASP8AP2 caspase 8 associated protein 2
CD46 CD46 molecule, complement regulatory protein
COMMD8 COMM domain containing 8
DBR1 debranching RNA lariats 1
DNAJA2 DnaJ (Hsp40) homolog, subfamily A, member 2
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
E2F8 E2F transcription factor 8
EIF2AK3 eukaryotic translation initiation factor 2-alpha kinase 3
EML4 echinoderm microtubule associated protein like 4
EXOC5 exocyst complex component 5
FAM50B family with sequence similarity 50, member B
FASTKD5 FAST kinase domains 5
FER fer (fps/fes related) tyrosine kinase
FGF13 fibroblast growth factor 13
FZD3 frizzled class receptor 3
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GCLM glutamate-cysteine ligase, modifier subunit
GDE1 glycerophosphodiester phosphodiesterase 1
GJC1 gap junction protein, gamma 1, 45kDa
GLT8D2 glycosyltransferase 8 domain containing 2
GOLGA8B golgin A8 family, member B
GPALPP1 GPALPP motifs containing 1
GTF2I general transcription factor IIi
HNRNPF heterogeneous nuclear ribonucleoprotein F
HSPA4L heat shock 70kDa protein 4-like
IFI6 interferon, alpha-inducible protein 6
IMPAD1 inositol monophosphatase domain containing 1
JMJD1C jumonji domain containing 1C
KCTD9 potassium channel tetramerization domain containing 9
KDM3A lysine (K)-specific demethylase 3A
LMAN1 lectin, mannose-binding, 1
LMBRD1 LMBR1 domain containing 1
MAGEA6 melanoma antigen family A6
MAGEF1 melanoma antigen family F1
MAGOH mago-nashi homolog, proliferation-associated (Drosophila)
MANEA mannosidase, endo-alpha
MAP3K2 mitogen-activated protein kinase kinase kinase 2
MBTPS2 membrane-bound transcription factor peptidase, site 2
MCTP1 multiple C2 domains, transmembrane 1
NAE1 NEDD8 activating enzyme E1 subunit 1
NMD3 NMD3 ribosome export adaptor
NRBF2 nuclear receptor binding factor 2
OARD1 O-acyl-ADP-ribose deacylase 1
OSBPL11 oxysterol binding protein-like 11
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
OVGP1 oviductal glycoprotein 1, 120kDa
OXR1 oxidation resistance 1
PALMD palmdelphin
PBK PDZ binding kinase
PDGFRL platelet-derived growth factor receptor-like
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PGM3 phosphoglucomutase 3
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent)
PRKRA protein kinase, interferon-inducible double stranded RNA dependent activator
PSAT1 phosphoserine aminotransferase 1
RCBTB2 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
RIT1 Ras-like without CAAX 1
RNF121 ring finger protein 121
RRN3 RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
RSL24D1 ribosomal L24 domain containing 1
SCAF8 SR-related CTD-associated factor 8
SCRN3 secernin 3
SCYL2 SCY1-like 2 (S. cerevisiae)
SEC24B SEC24 family member B
SELT selenoprotein T
SERINC5 serine incorporator 5
SETD8 SET domain containing (lysine methyltransferase) 8
SGMS1 sphingomyelin synthase 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SLBP stem-loop binding protein
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC35A5 solute carrier family 35, member A5
TAF1A TATA box binding protein (TBP)-associated factor, RNA polymerase I, A, 48kDa
TGDS TDP-glucose 4,6-dehydratase
TMEM230 transmembrane protein 230
TMEM242 transmembrane protein 242
TMOD3 tropomodulin 3 (ubiquitous)
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae)
USP6NL USP6 N-terminal like
WRB tryptophan rich basic protein
ZNF134 zinc finger protein 134
ZNF227 zinc finger protein 227
ZNF280D zinc finger protein 280D
ZNF350 zinc finger protein 350
ZNF770 zinc finger protein 770
ZW10 zw10 kinetochore protein