sulmazole-4009 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulmazole-4009 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A1CF APOBEC1 complementation factor
ABCC3 ATP-binding cassette, sub-family C (CFTR/MRP), member 3
ABCC9 ATP-binding cassette, sub-family C (CFTR/MRP), member 9
ACTA2 actin, alpha 2, smooth muscle, aorta
ADGRE3 adhesion G protein-coupled receptor E3
AKAP5 A kinase (PRKA) anchor protein 5
AMACR alpha-methylacyl-CoA racemase
AMH anti-Mullerian hormone
APOE apolipoprotein E
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
BAIAP3 BAI1-associated protein 3
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
C10ORF12 chromosome 10 open reading frame 12
CALHM2 calcium homeostasis modulator 2
CAMTA1 calmodulin binding transcription activator 1
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDC42 cell division cycle 42
CDKN1C cyclin-dependent kinase inhibitor 1C (p57, Kip2)
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CFDP1 craniofacial development protein 1
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39)
CLCN6 chloride channel, voltage-sensitive 6
CLDN1 claudin 1
COBL cordon-bleu WH2 repeat protein
COMT catechol-O-methyltransferase
CSPG4 chondroitin sulfate proteoglycan 4
CST8 cystatin 8 (cystatin-related epididymal specific)
DLGAP2 discs, large (Drosophila) homolog-associated protein 2
DPF3 D4, zinc and double PHD fingers, family 3
DZIP1 DAZ interacting zinc finger protein 1
FAM162A family with sequence similarity 162, member A
FGFR1 fibroblast growth factor receptor 1
FILIP1L filamin A interacting protein 1-like
FLJ11292
GAL3ST4 galactose-3-O-sulfotransferase 4
GDF10 growth differentiation factor 10
GIPR gastric inhibitory polypeptide receptor
GOLGA2P5 golgin A2 pseudogene 5
HEMK1 HemK methyltransferase family member 1
HOXD13 homeobox D13
HTR7P1 5-hydroxytryptamine (serotonin) receptor 7 pseudogene 1
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IMPG1 interphotoreceptor matrix proteoglycan 1
ITFG2 integrin alpha FG-GAP repeat containing 2
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KCNH6 potassium channel, voltage gated eag related subfamily H, member 6
KIAA1109 KIAA1109
KIF1A kinesin family member 1A
KLHL23 kelch-like family member 23
LAT2 linker for activation of T cells family, member 2
LDHC lactate dehydrogenase C
LINC00597 long intergenic non-protein coding RNA 597
LOC284244 uncharacterized LOC284244
LPCAT4 lysophosphatidylcholine acyltransferase 4
LRRN3 leucine rich repeat neuronal 3
MAK male germ cell-associated kinase
MATN1 matrilin 1, cartilage matrix protein
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
MTRF1L mitochondrial translational release factor 1-like
MYBPC3 myosin binding protein C, cardiac
NGLY1 N-glycanase 1
NPFFR1 neuropeptide FF receptor 1
OSBPL10 oxysterol binding protein-like 10
PADI2 peptidyl arginine deiminase, type II
PAK7 p21 protein (Cdc42/Rac)-activated kinase 7
PKP4 plakophilin 4
PLCL2 phospholipase C-like 2
PNMAL1 paraneoplastic Ma antigen family-like 1
POFUT1 protein O-fucosyltransferase 1
PPP2R2B protein phosphatase 2, regulatory subunit B, beta
PRDM9 PR domain containing 9
PRKCA protein kinase C, alpha
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RNGTT RNA guanylyltransferase and 5'-phosphatase
SAGE1 sarcoma antigen 1
SGSM3 small G protein signaling modulator 3
SIRPB1 signal-regulatory protein beta 1
SLC16A7 solute carrier family 16 (monocarboxylate transporter), member 7
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SPON1 spondin 1, extracellular matrix protein
SRPX2 sushi-repeat containing protein, X-linked 2
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
SUSD5 sushi domain containing 5
TADA2A transcriptional adaptor 2A
TBX6 T-box 6
TFCP2L1 transcription factor CP2-like 1
TLE1 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
TLX3 T-cell leukemia homeobox 3
TNK2 tyrosine kinase, non-receptor, 2
TPTE transmembrane phosphatase with tensin homology
TRD T cell receptor delta locus
TTC12 tetratricopeptide repeat domain 12
TTC30A tetratricopeptide repeat domain 30A
TTC9 tetratricopeptide repeat domain 9
USP2 ubiquitin specific peptidase 2
WHSC1L1 Wolf-Hirschhorn syndrome candidate 1-like 1
XYLB xylulokinase homolog (H. influenzae)
ZCCHC11 zinc finger, CCHC domain containing 11

decreased expression

Symbol Name
ARC activity-regulated cytoskeleton-associated protein
ARMCX4 armadillo repeat containing, X-linked 4
BGLAP bone gamma-carboxyglutamate (gla) protein
BST1 bone marrow stromal cell antigen 1
C17ORF53 chromosome 17 open reading frame 53
C5ORF45 chromosome 5 open reading frame 45
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDC42EP1 CDC42 effector protein (Rho GTPase binding) 1
CDON cell adhesion associated, oncogene regulated
CHPF chondroitin polymerizing factor
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNNM1 cyclin and CBS domain divalent metal cation transport mediator 1
DMBT1 deleted in malignant brain tumors 1
DNAH7 dynein, axonemal, heavy chain 7
ELOVL4 ELOVL fatty acid elongase 4
EMP3 epithelial membrane protein 3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
ERO1LB ERO1-like beta (S. cerevisiae)
FAM118A family with sequence similarity 118, member A
FBXL15 F-box and leucine-rich repeat protein 15
FBXO2 F-box protein 2
GATB glutamyl-tRNA(Gln) amidotransferase, subunit B
GCHFR GTP cyclohydrolase I feedback regulator
GJA9 gap junction protein, alpha 9, 59kDa
GNA14 guanine nucleotide binding protein (G protein), alpha 14
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GRM4 glutamate receptor, metabotropic 4
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HHAT hedgehog acyltransferase
HOMER2 homer scaffolding protein 2
HOXA1 homeobox A1
HSPB6 heat shock protein, alpha-crystallin-related, B6
IFI44L interferon-induced protein 44-like
ITPKC inositol-trisphosphate 3-kinase C
KDM8 lysine (K)-specific demethylase 8
KHDRBS2 KH domain containing, RNA binding, signal transduction associated 2
KRT6A keratin 6A, type II
KRT8P12 keratin 8 pseudogene 12
LIFR leukemia inhibitory factor receptor alpha
LMO2 LIM domain only 2 (rhombotin-like 1)
MBTPS2 membrane-bound transcription factor peptidase, site 2
MMP3 matrix metallopeptidase 3
MMP9 matrix metallopeptidase 9
NAG18 NAG18 mRNA
NDP Norrie disease (pseudoglioma)
NECAP2 NECAP endocytosis associated 2
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
NPM3 nucleophosmin/nucleoplasmin 3
NT5DC3 5'-nucleotidase domain containing 3
NT5M 5',3'-nucleotidase, mitochondrial
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
PARD6A par-6 family cell polarity regulator alpha
PDE8B phosphodiesterase 8B
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PIP prolactin-induced protein
PLAG1 pleiomorphic adenoma gene 1
PLCD1 phospholipase C, delta 1
PLD3 phospholipase D family, member 3
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLXNB3 plexin B3
PORCN porcupine homolog (Drosophila)
PRPH peripherin
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)
RAB35 RAB35, member RAS oncogene family
RPGRIP1L RPGRIP1-like
RPH3AL rabphilin 3A-like (without C2 domains)
RUSC2 RUN and SH3 domain containing 2
S100A4 S100 calcium binding protein A4
SCUBE3 signal peptide, CUB domain, EGF-like 3
SETD8 SET domain containing (lysine methyltransferase) 8
SLAMF7 SLAM family member 7
SLC39A7 solute carrier family 39 (zinc transporter), member 7
SLC6A9 solute carrier family 6 (neurotransmitter transporter, glycine), member 9
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SND1-IT1 SND1 intronic transcript 1
SSBP3 single stranded DNA binding protein 3
SSTR4 somatostatin receptor 4
STAC SH3 and cysteine rich domain
STARD3 StAR-related lipid transfer (START) domain containing 3
STX5 syntaxin 5
TCTN1 tectonic family member 1
TEX40 testis expressed 40
TLN1 talin 1
TMEM132A transmembrane protein 132A
TNFSF9 tumor necrosis factor (ligand) superfamily, member 9
TRIM21 tripartite motif containing 21
TSPAN1 tetraspanin 1
TXK TXK tyrosine kinase
WDR18 WD repeat domain 18
YPEL1 yippee-like 1 (Drosophila)
ZBTB6 zinc finger and BTB domain containing 6
ZNF268 zinc finger protein 268
ZNF492 zinc finger protein 492
ZNF747 zinc finger protein 747