sulfathiazole-4769 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the sulfathiazole-4769 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRB3 adhesion G protein-coupled receptor B3
AGFG2 ArfGAP with FG repeats 2
AKR1B1 aldo-keto reductase family 1, member B1 (aldose reductase)
APC adenomatous polyposis coli
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12
ART1 ADP-ribosyltransferase 1
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BGN biglycan
BHMT2 betaine--homocysteine S-methyltransferase 2
C14ORF1 chromosome 14 open reading frame 1
C21ORF2 chromosome 21 open reading frame 2
CD209 CD209 molecule
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CDH10 cadherin 10, type 2 (T2-cadherin)
CEMP1 cementum protein 1
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CST4 cystatin S
CTSF cathepsin F
CYP2U1 cytochrome P450, family 2, subfamily U, polypeptide 1
DAGLA diacylglycerol lipase, alpha
DCAF4 DDB1 and CUL4 associated factor 4
DGCR6L DiGeorge syndrome critical region gene 6-like
ELOVL2 ELOVL fatty acid elongase 2
ERN1 endoplasmic reticulum to nucleus signaling 1
FAM198B family with sequence similarity 198, member B
FBLN1 fibulin 1
FCF1 FCF1 rRNA-processing protein
FGFR2 fibroblast growth factor receptor 2
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila)
GBP1 guanylate binding protein 1, interferon-inducible
GJB3 gap junction protein, beta 3, 31kDa
GPR3 G protein-coupled receptor 3
GUSBP3 glucuronidase, beta pseudogene 3
HDAC9 histone deacetylase 9
HIPK2 homeodomain interacting protein kinase 2
HRH2 histamine receptor H2
IGHG1 immunoglobulin heavy constant gamma 1 (G1m marker)
IRF4 interferon regulatory factor 4
IRS4 insulin receptor substrate 4
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1
JAK3 Janus kinase 3
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KCNH2 potassium channel, voltage gated eag related subfamily H, member 2
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KDM5C lysine (K)-specific demethylase 5C
KRT32 keratin 32, type I
LILRA4 leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 4
LRRN3 leucine rich repeat neuronal 3
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAS1 MAS1 proto-oncogene, G protein-coupled receptor
MCOLN3 mucolipin 3
MPPE1 metallophosphoesterase 1
NCAM1 neural cell adhesion molecule 1
NEFM neurofilament, medium polypeptide
NLGN1 neuroligin 1
NR5A2 nuclear receptor subfamily 5, group A, member 2
OLFM1 olfactomedin 1
OPRM1 opioid receptor, mu 1
PDE4B phosphodiesterase 4B, cAMP-specific
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHEX phosphate regulating endopeptidase homolog, X-linked
PI4K2A phosphatidylinositol 4-kinase type 2 alpha
PIP prolactin-induced protein
PLAG1 pleiomorphic adenoma gene 1
POU2F2 POU class 2 homeobox 2
PPP1R2P9 protein phosphatase 1, regulatory (inhibitor) subunit 2 pseudogene 9
PRB1 proline-rich protein BstNI subfamily 1
PRPH2 peripherin 2 (retinal degeneration, slow)
RARB retinoic acid receptor, beta
REC8 REC8 meiotic recombination protein
RFX2 regulatory factor X, 2 (influences HLA class II expression)
RPLP2 ribosomal protein, large, P2
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNX1 runt-related transcription factor 1
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SFTPB surfactant protein B
SIPA1L3 signal-induced proliferation-associated 1 like 3
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3
SLC39A9 solute carrier family 39, member 9
SLCO1B1 solute carrier organic anion transporter family, member 1B1
SMAD5 SMAD family member 5
SOS2 son of sevenless homolog 2 (Drosophila)
SSTR5 somatostatin receptor 5
STX7 syntaxin 7
SYDE1 synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
TBX3 T-box 3
TGFBR3 transforming growth factor, beta receptor III
THPO thrombopoietin
TMEM212 transmembrane protein 212
TSPAN2 tetraspanin 2
TSSK2 testis-specific serine kinase 2
VTCN1 V-set domain containing T cell activation inhibitor 1
ZNF222 zinc finger protein 222
ZNF41 zinc finger protein 41
ZNF589 zinc finger protein 589

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADORA2B adenosine A2b receptor
BCL2L2 BCL2-like 2
C2ORF54 chromosome 2 open reading frame 54
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CDC73 cell division cycle 73
CENPQ centromere protein Q
CLCN5 chloride channel, voltage-sensitive 5
CLDN4 claudin 4
CLEC16A C-type lectin domain family 16, member A
CLIC3 chloride intracellular channel 3
COQ6 coenzyme Q6 monooxygenase
CORT cortistatin
CRIP1 cysteine-rich protein 1 (intestinal)
CRYL1 crystallin, lambda 1
DNM1 dynamin 1
EIF5A2 eukaryotic translation initiation factor 5A2
ETAA1 Ewing tumor-associated antigen 1
F3 coagulation factor III (thromboplastin, tissue factor)
FAM120C family with sequence similarity 120C
FANCE Fanconi anemia, complementation group E
FBXL15 F-box and leucine-rich repeat protein 15
FLOT2 flotillin 2
FSTL3 follistatin-like 3 (secreted glycoprotein)
GAN gigaxonin
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GINS4 GINS complex subunit 4 (Sld5 homolog)
GRB7 growth factor receptor-bound protein 7
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IFI6 interferon, alpha-inducible protein 6
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFT140 intraflagellar transport 140
IGFBP2 insulin-like growth factor binding protein 2, 36kDa
IGSF1 immunoglobulin superfamily, member 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KLHL36 kelch-like family member 36
LAMA3 laminin, alpha 3
LOC730101 uncharacterized LOC730101
LRP5L low density lipoprotein receptor-related protein 5-like
LYRM2 LYR motif containing 2
MANBA mannosidase, beta A, lysosomal
MAPK3 mitogen-activated protein kinase 3
MFAP2 microfibrillar-associated protein 2
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor)
MTHFS 5,10-methenyltetrahydrofolate synthetase (5-formyltetrahydrofolate cyclo-ligase)
NABP2 nucleic acid binding protein 2
NKAIN1 Na+/K+ transporting ATPase interacting 1
NOTCH1 notch 1
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OGDH oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide)
OR2F1 olfactory receptor, family 2, subfamily F, member 1 (gene/pseudogene)
PACS1 phosphofurin acidic cluster sorting protein 1
PANK4 pantothenate kinase 4
PIGL phosphatidylinositol glycan anchor biosynthesis, class L
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLD3 phospholipase D family, member 3
PLEKHO1 pleckstrin homology domain containing, family O member 1
POLD1 polymerase (DNA directed), delta 1, catalytic subunit
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RFWD3 ring finger and WD repeat domain 3
RMND1 required for meiotic nuclear division 1 homolog (S. cerevisiae)
RNF130 ring finger protein 130
S100A2 S100 calcium binding protein A2
S100A6 S100 calcium binding protein A6
SCMH1 sex comb on midleg homolog 1 (Drosophila)
SERPINB6 serpin peptidase inhibitor, clade B (ovalbumin), member 6
SETD8 SET domain containing (lysine methyltransferase) 8
SH3GLB2 SH3-domain GRB2-like endophilin B2
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SLC12A9 solute carrier family 12, member 9
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC44A1 solute carrier family 44 (choline transporter), member 1
SMUG1 single-strand-selective monofunctional uracil-DNA glycosylase 1
SNAI2 snail family zinc finger 2
SPAG4 sperm associated antigen 4
STAG3L1 stromal antigen 3-like 1 (pseudogene)
STXBP2 syntaxin binding protein 2
SUSD6 sushi domain containing 6
TIMM17B translocase of inner mitochondrial membrane 17 homolog B (yeast)
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast)
TSPO translocator protein (18kDa)
UBIAD1 UbiA prenyltransferase domain containing 1
UNC119 unc-119 homolog (C. elegans)
UTP11L UTP11-like, U3 small nucleolar ribonucleoprotein (yeast)
VPS33A vacuolar protein sorting 33 homolog A (S. cerevisiae)
VPS39 vacuolar protein sorting 39 homolog (S. cerevisiae)
WDR18 WD repeat domain 18
XPNPEP3 X-prolyl aminopeptidase 3, mitochondrial
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZFYVE21 zinc finger, FYVE domain containing 21
ZNF394 zinc finger protein 394
ZNF428 zinc finger protein 428
ZNF446 zinc finger protein 446
ZNF652 zinc finger protein 652
ZNF692 zinc finger protein 692
ZNF91 zinc finger protein 91
ZNHIT2 zinc finger, HIT-type containing 2