sulfapyridine-7151 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the sulfapyridine-7151 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACSM3 acyl-CoA synthetase medium-chain family member 3
AKR1B10 aldo-keto reductase family 1, member B10 (aldose reductase)
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ALMS1 Alstrom syndrome protein 1
APOA1 apolipoprotein A-I
APP amyloid beta (A4) precursor protein
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGAP1 Rho GTPase activating protein 1
ARIH2 ariadne RBR E3 ubiquitin protein ligase 2
ARMC8 armadillo repeat containing 8
ASAP3 ArfGAP with SH3 domain, ankyrin repeat and PH domain 3
ASTE1 asteroid homolog 1 (Drosophila)
ATP6V0E1 ATPase, H+ transporting, lysosomal 9kDa, V0 subunit e1
ATXN7L1 ataxin 7-like 1
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BDKRB1 bradykinin receptor B1
BIN1 bridging integrator 1
C18ORF25 chromosome 18 open reading frame 25
C7ORF43 chromosome 7 open reading frame 43
CDK10 cyclin-dependent kinase 10
CLN3 ceroid-lipofuscinosis, neuronal 3
COL6A1 collagen, type VI, alpha 1
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DENND4A DENN/MADD domain containing 4A
DUSP7 dual specificity phosphatase 7
EGFR epidermal growth factor receptor
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3
EPAS1 endothelial PAS domain protein 1
ESRRA estrogen-related receptor alpha
FCMR Fc fragment of IgM receptor
FLJ10038 uncharacterized protein FLJ10038
FOXO1 forkhead box O1
GK glycerol kinase
GNA11 guanine nucleotide binding protein (G protein), alpha 11 (Gq class)
GOLGA2 golgin A2
H2AFX H2A histone family, member X
HDLBP high density lipoprotein binding protein
HSD17B8 hydroxysteroid (17-beta) dehydrogenase 8
IFI6 interferon, alpha-inducible protein 6
IFITM1 interferon induced transmembrane protein 1
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
JAK2 Janus kinase 2
KLHDC4 kelch domain containing 4
KRT34 keratin 34, type I
LIMK2 LIM domain kinase 2
LOC202181 SUMO-interacting motifs containing 1 pseudogene
MAMLD1 mastermind-like domain containing 1
MAPK14 mitogen-activated protein kinase 14
MECOM MDS1 and EVI1 complex locus
MGEA5 meningioma expressed antigen 5 (hyaluronidase)
NF2 neurofibromin 2 (merlin)
NID1 nidogen 1
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
NUFIP1 nuclear fragile X mental retardation protein interacting protein 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
PBXIP1 pre-B-cell leukemia homeobox interacting protein 1
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PEX26 peroxisomal biogenesis factor 26
PPARD peroxisome proliferator-activated receptor delta
PVT1 Pvt1 oncogene (non-protein coding)
RAP1GAP RAP1 GTPase activating protein
RBKS ribokinase
RCN3 reticulocalbin 3, EF-hand calcium binding domain
RGS4 regulator of G-protein signaling 4
RIN1 Ras and Rab interactor 1
RNF126P1 ring finger protein 126 pseudogene 1
RPL23AP32 ribosomal protein L23a pseudogene 32
RTEL1 regulator of telomere elongation helicase 1
SCARA3 scavenger receptor class A, member 3
SCARB1 scavenger receptor class B, member 1
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SFT2D2 SFT2 domain containing 2
SGSM3 small G protein signaling modulator 3
SIAH1 siah E3 ubiquitin protein ligase 1
SLC2A9 solute carrier family 2 (facilitated glucose transporter), member 9
SLC46A3 solute carrier family 46, member 3
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPATA2L spermatogenesis associated 2-like
ST14 suppression of tumorigenicity 14 (colon carcinoma)
STAM2 signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
SUN1 Sad1 and UNC84 domain containing 1
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
SYNPO synaptopodin
TAOK3 TAO kinase 3
TBXAS1 thromboxane A synthase 1 (platelet)
TGFA transforming growth factor, alpha
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VWA8 von Willebrand factor A domain containing 8
WDR60 WD repeat domain 60
ZBED4 zinc finger, BED-type containing 4
ZFP36L2 ZFP36 ring finger protein-like 2
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF202 zinc finger protein 202
ZNF839 zinc finger protein 839

decreased expression

Symbol Name
ABHD17B abhydrolase domain containing 17B
ABT1 activator of basal transcription 1
ANXA10 annexin A10
ASH1L ash1 (absent, small, or homeotic)-like (Drosophila)
ATAD5 ATPase family, AAA domain containing 5
BDNF brain-derived neurotrophic factor
BEX4 brain expressed, X-linked 4
C16ORF59 chromosome 16 open reading frame 59
C17ORF80 chromosome 17 open reading frame 80
CAPN5 calpain 5
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CHMP7 charged multivesicular body protein 7
CHST10 carbohydrate sulfotransferase 10
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDX31 DEAD (Asp-Glu-Ala-Asp) box polypeptide 31
ECM1 extracellular matrix protein 1
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGLN2 egl-9 family hypoxia-inducible factor 2
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELP3 elongator acetyltransferase complex subunit 3
FANCF Fanconi anemia, complementation group F
FBXO46 F-box protein 46
FBXW4 F-box and WD repeat domain containing 4
GMIP GEM interacting protein
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
GPALPP1 GPALPP motifs containing 1
GRHL2 grainyhead-like 2 (Drosophila)
HCFC2 host cell factor C2
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HMGB3P1 high mobility group box 3 pseudogene 1
HOXC10 homeobox C10
HSPA4L heat shock 70kDa protein 4-like
INCENP inner centromere protein antigens 135/155kDa
IPPK inositol 1,3,4,5,6-pentakisphosphate 2-kinase
JADE1 jade family PHD finger 1
JAM3 junctional adhesion molecule 3
KIAA1462 KIAA1462
KIF13B kinesin family member 13B
KLHL3 kelch-like family member 3
LINC00339 long intergenic non-protein coding RNA 339
LINS lines homolog (Drosophila)
LRIG2 leucine-rich repeats and immunoglobulin-like domains 2
METRN meteorin, glial cell differentiation regulator
MICALL2 MICAL-like 2
MNX1 motor neuron and pancreas homeobox 1
MOCOS molybdenum cofactor sulfurase
NAV2 neuron navigator 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NPDC1 neural proliferation, differentiation and control, 1
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
OCLN occludin
ODF2 outer dense fiber of sperm tails 2
OLFML2A olfactomedin-like 2A
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
PARD6A par-6 family cell polarity regulator alpha
PHC1 polyhomeotic homolog 1 (Drosophila)
PHLDA3 pleckstrin homology-like domain, family A, member 3
PLA2G15 phospholipase A2, group XV
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PRR3 proline rich 3
PYCARD PYD and CARD domain containing
RAB3A RAB3A, member RAS oncogene family
RASA2 RAS p21 protein activator 2
REEP4 receptor accessory protein 4
RFTN1 raftlin, lipid raft linker 1
RNF121 ring finger protein 121
ROGDI rogdi homolog (Drosophila)
SETD8 SET domain containing (lysine methyltransferase) 8
SLC31A2 solute carrier family 31 (copper transporter), member 2
SLC35C2 solute carrier family 35 (GDP-fucose transporter), member C2
SLC36A1 solute carrier family 36 (proton/amino acid symporter), member 1
SLC4A1AP solute carrier family 4 (anion exchanger), member 1, adaptor protein
SMARCD2 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 2
SNTA1 syntrophin, alpha 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
THBS3 thrombospondin 3
TMEM242 transmembrane protein 242
TOR4A torsin family 4, member A
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TSPYL2 TSPY-like 2
UBTD1 ubiquitin domain containing 1
ULBP2 UL16 binding protein 2
UNC13B unc-13 homolog B (C. elegans)
USB1 U6 snRNA biogenesis 1
XYLT2 xylosyltransferase II
ZBED1 zinc finger, BED-type containing 1
ZBTB44 zinc finger and BTB domain containing 44
ZMYM3 zinc finger, MYM-type 3
ZNF273 zinc finger protein 273
ZNF552 zinc finger protein 552
ZNF574 zinc finger protein 574
ZNF85 zinc finger protein 85