sulfapyridine-6799 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulfapyridine-6799 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ALOX5 arachidonate 5-lipoxygenase
ANKMY1 ankyrin repeat and MYND domain containing 1
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARTN artemin
ASCL1 achaete-scute family bHLH transcription factor 1
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
CACNA1A calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
CAMTA2 calmodulin binding transcription activator 2
CD52 CD52 molecule
CDHR2 cadherin-related family member 2
CHKB choline kinase beta
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLCN7 chloride channel, voltage-sensitive 7
CLGN calmegin
CRTC1 CREB regulated transcription coactivator 1
DCBLD2 discoidin, CUB and LCCL domain containing 2
DICER1 dicer 1, ribonuclease type III
DIO2 deiodinase, iodothyronine, type II
DOCK5 dedicator of cytokinesis 5
DSCC1 DNA replication and sister chromatid cohesion 1
DUSP13 dual specificity phosphatase 13
EPM2A epilepsy, progressive myoclonus type 2A, Lafora disease (laforin)
FGB fibrinogen beta chain
FHOD1 formin homology 2 domain containing 1
FLJ11710 uncharacterized protein FLJ11710
FOXN2 forkhead box N2
FSCN1 fascin actin-bundling protein 1
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GAB1 GRB2-associated binding protein 1
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GSTTP1 glutathione S-transferase theta pseudogene 1
GZMK granzyme K (granzyme 3; tryptase II)
HBEGF heparin-binding EGF-like growth factor
HMGA1 high mobility group AT-hook 1
IGFBP5 insulin-like growth factor binding protein 5
IL20RA interleukin 20 receptor, alpha
IL36A interleukin 36, alpha
IL5RA interleukin 5 receptor, alpha
IRS2 insulin receptor substrate 2
ITGA3 integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
ITM2C integral membrane protein 2C
KAT6A K(lysine) acetyltransferase 6A
KLK8 kallikrein-related peptidase 8
KMT2A lysine (K)-specific methyltransferase 2A
LAMB4 laminin, beta 4
LBX1 ladybird homeobox 1
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAL mal, T-cell differentiation protein
MARK4 MAP/microtubule affinity-regulating kinase 4
MAST4 microtubule associated serine/threonine kinase family member 4
MKL1 megakaryoblastic leukemia (translocation) 1
MTA2 metastasis associated 1 family, member 2
MYH8 myosin, heavy chain 8, skeletal muscle, perinatal
OGG1 8-oxoguanine DNA glycosylase
PDE4C phosphodiesterase 4C, cAMP-specific
PDE8B phosphodiesterase 8B
PDXK pyridoxal (pyridoxine, vitamin B6) kinase
PEX26 peroxisomal biogenesis factor 26
PGAP1 post-GPI attachment to proteins 1
PGR progesterone receptor
PHF3 PHD finger protein 3
PLD3 phospholipase D family, member 3
PLEKHG3 pleckstrin homology domain containing, family G (with RhoGef domain) member 3
POM121L2 POM121 transmembrane nucleoporin-like 2
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PRB1 proline-rich protein BstNI subfamily 1
PRKACA protein kinase, cAMP-dependent, catalytic, alpha
PSG3 pregnancy specific beta-1-glycoprotein 3
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C)
PXN paxillin
RASAL2 RAS protein activator like 2
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF4 Ras association (RalGDS/AF-6) domain family member 4
RBM5 RNA binding motif protein 5
RND2 Rho family GTPase 2
SAYSD1 SAYSVFN motif domain containing 1
SECISBP2L SECIS binding protein 2-like
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SETBP1 SET binding protein 1
SLC35E2 solute carrier family 35, member E2
STK4 serine/threonine kinase 4
STX1A syntaxin 1A (brain)
SULT4A1 sulfotransferase family 4A, member 1
TFAP2B transcription factor AP-2 beta (activating enhancer binding protein 2 beta)
TFE3 transcription factor binding to IGHM enhancer 3
TK2 thymidine kinase 2, mitochondrial
TRD T cell receptor delta locus
TTC38 tetratricopeptide repeat domain 38
UNC119 unc-119 homolog (C. elegans)
USP46 ubiquitin specific peptidase 46
VASH2 vasohibin 2
WDR62 WD repeat domain 62
ZC3H7B zinc finger CCCH-type containing 7B
ZFP36L1 ZFP36 ring finger protein-like 1
ZFYVE9 zinc finger, FYVE domain containing 9
ZNF202 zinc finger protein 202
ZNF440 zinc finger protein 440

decreased expression

Symbol Name
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
AFF4 AF4/FMR2 family, member 4
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ALPK1 alpha-kinase 1
ANXA2P3 annexin A2 pseudogene 3
ARRB1 arrestin, beta 1
B9D2 B9 protein domain 2
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BHLHB9 basic helix-loop-helix domain containing, class B, 9
CARD8 caspase recruitment domain family, member 8
CCDC69 coiled-coil domain containing 69
CENPJ centromere protein J
CGREF1 cell growth regulator with EF-hand domain 1
CLSPN claspin
CORT cortistatin
CRY2 cryptochrome circadian clock 2
DDX43 DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
DNAJC7 DnaJ (Hsp40) homolog, subfamily C, member 7
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
ETAA1 Ewing tumor-associated antigen 1
FAM118A family with sequence similarity 118, member A
FAM86C1 family with sequence similarity 86, member C1
FBXW12 F-box and WD repeat domain containing 12
GINS4 GINS complex subunit 4 (Sld5 homolog)
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GTF2H3 general transcription factor IIH, polypeptide 3, 34kDa
GTF2I general transcription factor IIi
GUSBP3 glucuronidase, beta pseudogene 3
HIRA histone cell cycle regulator
HIST1H1D histone cluster 1, H1d
HMGB3P1 high mobility group box 3 pseudogene 1
ICK intestinal cell (MAK-like) kinase
IFI35 interferon-induced protein 35
IFI6 interferon, alpha-inducible protein 6
IPP intracisternal A particle-promoted polypeptide
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor)
JMJD4 jumonji domain containing 4
KIAA0894 KIAA0894 protein
KLHL21 kelch-like family member 21
LINS lines homolog (Drosophila)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
MAGT1 magnesium transporter 1
MANBA mannosidase, beta A, lysosomal
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBTD1 mbt domain containing 1
MGC12488
MOCS3 molybdenum cofactor synthesis 3
MVP major vault protein
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NPIPB15 nuclear pore complex interacting protein family, member B15
NUBPL nucleotide binding protein-like
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PCDHGB5 protocadherin gamma subfamily B, 5
PHACTR4 phosphatase and actin regulator 4
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PRICKLE3 prickle homolog 3 (Drosophila)
PROCR protein C receptor, endothelial
PRR14L proline rich 14-like
RFTN1 raftlin, lipid raft linker 1
RGS19 regulator of G-protein signaling 19
RGS2 regulator of G-protein signaling 2
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RNF126P1 ring finger protein 126 pseudogene 1
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SPAG4 sperm associated antigen 4
STK19 serine/threonine kinase 19
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
SYCP2 synaptonemal complex protein 2
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TEP1 telomerase-associated protein 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM104 transmembrane protein 104
TMEM39B transmembrane protein 39B
TOM1 target of myb1 (chicken)
TRAPPC11 trafficking protein particle complex 11
TRMT2B tRNA methyltransferase 2 homolog B (S. cerevisiae)
TRPC4AP transient receptor potential cation channel, subfamily C, member 4 associated protein
TTBK2 tau tubulin kinase 2
TUBA3C tubulin, alpha 3c
USP36 ubiquitin specific peptidase 36
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VEZT vezatin, adherens junctions transmembrane protein
WDR76 WD repeat domain 76
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2
ZNF160 zinc finger protein 160
ZNF430 zinc finger protein 430
ZNF442 zinc finger protein 442
ZNF468 zinc finger protein 468
ZNF623 zinc finger protein 623
ZNF652 zinc finger protein 652
ZNF675 zinc finger protein 675
ZNF721 zinc finger protein 721
ZNF768 zinc finger protein 768
ZNF83 zinc finger protein 83
ZNF85 zinc finger protein 85