sulfanilamide-6810 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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197 genes differentially expressed following the sulfanilamide-6810 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAK1 AP2 associated kinase 1
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACBD4 acyl-CoA binding domain containing 4
ADGRG1 adhesion G protein-coupled receptor G1
ADRBK1 adrenergic, beta, receptor kinase 1
AMACR alpha-methylacyl-CoA racemase
ANK1 ankyrin 1, erythrocytic
APLP1 amyloid beta (A4) precursor-like protein 1
APOE apolipoprotein E
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARNT aryl hydrocarbon receptor nuclear translocator
ASB1 ankyrin repeat and SOCS box containing 1
ATP11A ATPase, class VI, type 11A
BCO1 beta-carotene oxygenase 1
BIN1 bridging integrator 1
CACNA1G calcium channel, voltage-dependent, T type, alpha 1G subunit
CCDC132 coiled-coil domain containing 132
CDK12 cyclin-dependent kinase 12
CHRNA3 cholinergic receptor, nicotinic, alpha 3 (neuronal)
CLGN calmegin
CLSTN3 calsyntenin 3
CPQ carboxypeptidase Q
CRMP1 collapsin response mediator protein 1
CTIF CBP80/20-dependent translation initiation factor
CTSF cathepsin F
CYP2C9 cytochrome P450, family 2, subfamily C, polypeptide 9
DCBLD2 discoidin, CUB and LCCL domain containing 2
DFNB31 deafness, autosomal recessive 31
DUSP6 dual specificity phosphatase 6
EFNB3 ephrin-B3
ENPEP glutamyl aminopeptidase (aminopeptidase A)
ESR1 estrogen receptor 1
FADS2 fatty acid desaturase 2
FAM168A family with sequence similarity 168, member A
FBLN1 fibulin 1
FGD2 FYVE, RhoGEF and PH domain containing 2
FSHB follicle stimulating hormone, beta polypeptide
FYN FYN proto-oncogene, Src family tyrosine kinase
HCG4 HLA complex group 4 (non-protein coding)
HIST1H4C histone cluster 1, H4c
HIST1H4E histone cluster 1, H4e
HSPA1L heat shock 70kDa protein 1-like
HYAL3 hyaluronoglucosaminidase 3
IFI44 interferon-induced protein 44
IQCC IQ motif containing C
ITSN1 intersectin 1 (SH3 domain protein)
JRK Jrk homolog (mouse)
KIAA0754 KIAA0754
KLK7 kallikrein-related peptidase 7
KLK8 kallikrein-related peptidase 8
LAIR2 leukocyte-associated immunoglobulin-like receptor 2
LAX1 lymphocyte transmembrane adaptor 1
LGALS9 lectin, galactoside-binding, soluble, 9
LIMK1 LIM domain kinase 1
LIN7A lin-7 homolog A (C. elegans)
MMP25 matrix metallopeptidase 25
MR1 major histocompatibility complex, class I-related
MTMR7 myotubularin related protein 7
MYH14 myosin, heavy chain 14, non-muscle
MYL4 myosin, light chain 4, alkali; atrial, embryonic
NDRG2 NDRG family member 2
NEUROD6 neuronal differentiation 6
NPAT nuclear protein, ataxia-telangiectasia locus
NPY1R neuropeptide Y receptor Y1
NR2E3 nuclear receptor subfamily 2, group E, member 3
NRTN neurturin
NUP214 nucleoporin 214kDa
OR1G1 olfactory receptor, family 1, subfamily G, member 1
PCDHGA8 protocadherin gamma subfamily A, 8
PCNX pecanex homolog (Drosophila)
PEAK1 pseudopodium-enriched atypical kinase 1
PKNOX1 PBX/knotted 1 homeobox 1
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent)
PLAT plasminogen activator, tissue
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PPARD peroxisome proliferator-activated receptor delta
RPS4Y1 ribosomal protein S4, Y-linked 1
RUNDC3B RUN domain containing 3B
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEL1L sel-1 suppressor of lin-12-like (C. elegans)
SIK3 SIK family kinase 3
SLC19A3 solute carrier family 19 (thiamine transporter), member 3
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SOX9 SRY (sex determining region Y)-box 9
SPINK1 serine peptidase inhibitor, Kazal type 1
SPRR1A small proline-rich protein 1A
SRD5A3 steroid 5 alpha-reductase 3
STAT2 signal transducer and activator of transcription 2, 113kDa
TBC1D2 TBC1 domain family, member 2
TCP11L1 t-complex 11, testis-specific-like 1
TLE4 transducin-like enhancer of split 4
TMEM63A transmembrane protein 63A
TOR4A torsin family 4, member A
TTC9 tetratricopeptide repeat domain 9
UBXN1 UBX domain protein 1
VIPR2 vasoactive intestinal peptide receptor 2
WDR61 WD repeat domain 61
XYLB xylulokinase homolog (H. influenzae)
ZNF76 zinc finger protein 76

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif, 13
ALS2CL ALS2 C-terminal like
ANKRD2 ankyrin repeat domain 2 (stretch responsive muscle)
ANXA1 annexin A1
AP4M1 adaptor-related protein complex 4, mu 1 subunit
APOLD1 apolipoprotein L domain containing 1
ARSB arylsulfatase B
ASPHD1 aspartate beta-hydroxylase domain containing 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B9D2 B9 protein domain 2
C5AR2 complement component 5a receptor 2
CACNA2D2 calcium channel, voltage-dependent, alpha 2/delta subunit 2
CCDC71 coiled-coil domain containing 71
CHST10 carbohydrate sulfotransferase 10
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNKSR2 connector enhancer of kinase suppressor of Ras 2
CUL9 cullin 9
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
DNAL4 dynein, axonemal, light chain 4
DOC2A double C2-like domains, alpha
DSCAM Down syndrome cell adhesion molecule
ERCC4 excision repair cross-complementation group 4
ERN2 endoplasmic reticulum to nucleus signaling 2
FAM169A family with sequence similarity 169, member A
FER fer (fps/fes related) tyrosine kinase
FILIP1L filamin A interacting protein 1-like
FLRT3 fibronectin leucine rich transmembrane protein 3
GADD45G growth arrest and DNA-damage-inducible, gamma
GSTA4 glutathione S-transferase alpha 4
GSTTP1 glutathione S-transferase theta pseudogene 1
HDAC7 histone deacetylase 7
HIST1H2AI histone cluster 1, H2ai
HIST1H2BO histone cluster 1, H2bo
HMOX1 heme oxygenase 1
ICAM4 intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
IFI27 interferon, alpha-inducible protein 27
IFI6 interferon, alpha-inducible protein 6
IGFBP6 insulin-like growth factor binding protein 6
IL12RB1 interleukin 12 receptor, beta 1
IL4R interleukin 4 receptor
ITPKB inositol-trisphosphate 3-kinase B
KLHL36 kelch-like family member 36
KPNA5 karyopherin alpha 5 (importin alpha 6)
KREMEN2 kringle containing transmembrane protein 2
KRI1 KRI1 homolog (S. cerevisiae)
KRT15 keratin 15, type I
LGALS4 lectin, galactoside-binding, soluble, 4
LPXN leupaxin
LRP3 low density lipoprotein receptor-related protein 3
MUC3A mucin 3A, cell surface associated
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MXD3 MAX dimerization protein 3
MYL5 myosin, light chain 5, regulatory
NDE1 nudE neurodevelopment protein 1
NPIPB3 nuclear pore complex interacting protein family, member B3
PARG poly (ADP-ribose) glycohydrolase
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PHGDH phosphoglycerate dehydrogenase
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
POLL polymerase (DNA directed), lambda
PP14571 uncharacterized LOC100130449
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRF1 perforin 1 (pore forming protein)
PRR14L proline rich 14-like
QPCTL glutaminyl-peptide cyclotransferase-like
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RIN1 Ras and Rab interactor 1
ROM1 retinal outer segment membrane protein 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A9 S100 calcium binding protein A9
SDC3 syndecan 3
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SLC12A6 solute carrier family 12 (potassium/chloride transporter), member 6
SLC9A5 solute carrier family 9, subfamily A (NHE5, cation proton antiporter 5), member 5
SPINK4 serine peptidase inhibitor, Kazal type 4
SPINK5 serine peptidase inhibitor, Kazal type 5
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STARD5 StAR-related lipid transfer (START) domain containing 5
SUN2 Sad1 and UNC84 domain containing 2
THNSL2 threonine synthase-like 2 (S. cerevisiae)
TMEM180 transmembrane protein 180
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UPK3B uroplakin 3B
UPP1 uridine phosphorylase 1
VAX2 ventral anterior homeobox 2
VEZT vezatin, adherens junctions transmembrane protein
VGF VGF nerve growth factor inducible
ZBTB48 zinc finger and BTB domain containing 48
ZIC3 Zic family member 3
ZKSCAN3 zinc finger with KRAB and SCAN domains 3
ZNF205 zinc finger protein 205
ZNF282 zinc finger protein 282
ZNF442 zinc finger protein 442