sulfanilamide-3449 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the sulfanilamide-3449 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABL2 ABL proto-oncogene 2, non-receptor tyrosine kinase
ADAM22 ADAM metallopeptidase domain 22
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALPK1 alpha-kinase 1
ANAPC13 anaphase promoting complex subunit 13
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
ARMC4 armadillo repeat containing 4
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BTN3A1 butyrophilin, subfamily 3, member A1
C1QTNF3 C1q and tumor necrosis factor related protein 3
C2ORF27A chromosome 2 open reading frame 27A
CA4 carbonic anhydrase IV
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCNO cyclin O
CD8A CD8a molecule
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2
CLEC11A C-type lectin domain family 11, member A
COL16A1 collagen, type XVI, alpha 1
CROCC ciliary rootlet coiled-coil, rootletin
CXCR2 chemokine (C-X-C motif) receptor 2
DIO2 deiodinase, iodothyronine, type II
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DNM3 dynamin 3
DOK1 docking protein 1, 62kDa (downstream of tyrosine kinase 1)
EMID1 EMI domain containing 1
EPHB2 EPH receptor B2
ESR1 estrogen receptor 1
FGF6 fibroblast growth factor 6
FLJ22184
FPGS folylpolyglutamate synthase
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1
GLS2 glutaminase 2 (liver, mitochondrial)
GM2A GM2 ganglioside activator
GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
GPR137 G protein-coupled receptor 137
GRM7 glutamate receptor, metabotropic 7
HIST1H1D histone cluster 1, H1d
IFI6 interferon, alpha-inducible protein 6
IGFBP6 insulin-like growth factor binding protein 6
IL7R interleukin 7 receptor
ITGB5 integrin, beta 5
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KMT2A lysine (K)-specific methyltransferase 2A
LEPR leptin receptor
LMF2 lipase maturation factor 2
LOC399491
MAF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4 microtubule-associated protein 4
MAP9 microtubule-associated protein 9
MEGF9 multiple EGF-like-domains 9
MRPL41 mitochondrial ribosomal protein L41
NAAA N-acylethanolamine acid amidase
NCAPH2 non-SMC condensin II complex, subunit H2
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase
NKX3-2 NK3 homeobox 2
NUPR1 nuclear protein, transcriptional regulator, 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PAX5 paired box 5
PDLIM7 PDZ and LIM domain 7 (enigma)
PILRA paired immunoglobin-like type 2 receptor alpha
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PML promyelocytic leukemia
PRB4 proline-rich protein BstNI subfamily 4
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RAB6A RAB6A, member RAS oncogene family
RGS12 regulator of G-protein signaling 12
RNPEPL1 arginyl aminopeptidase (aminopeptidase B)-like 1
RPLP2 ribosomal protein, large, P2
SAMD9 sterile alpha motif domain containing 9
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SLC25A30 solute carrier family 25, member 30
SLC44A1 solute carrier family 44 (choline transporter), member 1
SOX12 SRY (sex determining region Y)-box 12
SOX9 SRY (sex determining region Y)-box 9
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
TFE3 transcription factor binding to IGHM enhancer 3
TICAM1 toll-like receptor adaptor molecule 1
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TM4SF5 transmembrane 4 L six family member 5
TMEM63A transmembrane protein 63A
TNFAIP1 tumor necrosis factor, alpha-induced protein 1 (endothelial)
TRPV6 transient receptor potential cation channel, subfamily V, member 6
TTLL5 tubulin tyrosine ligase-like family member 5
UBTD1 ubiquitin domain containing 1
UPP1 uridine phosphorylase 1
USP34 ubiquitin specific peptidase 34
UTRN utrophin
ZNF219 zinc finger protein 219
ZNF3 zinc finger protein 3
ZNF484 zinc finger protein 484
ZNF500 zinc finger protein 500
ZNF609 zinc finger protein 609

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ABCA5 ATP-binding cassette, sub-family A (ABC1), member 5
ABHD4 abhydrolase domain containing 4
ACADSB acyl-CoA dehydrogenase, short/branched chain
ACYP2 acylphosphatase 2, muscle type
ALG12 ALG12, alpha-1,6-mannosyltransferase
ASAP1-IT1 ASAP1 intronic transcript 1
BATF basic leucine zipper transcription factor, ATF-like
BTF3P12 basic transcription factor 3 pseudogene 12
C2ORF54 chromosome 2 open reading frame 54
C5 complement component 5
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CDR2L cerebellar degeneration-related protein 2-like
CHST10 carbohydrate sulfotransferase 10
CLCN2 chloride channel, voltage-sensitive 2
CLDN15 claudin 15
CRELD1 cysteine-rich with EGF-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DCAF10 DDB1 and CUL4 associated factor 10
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
EML4 echinoderm microtubule associated protein like 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
ERO1L ERO1-like (S. cerevisiae)
FAM131A family with sequence similarity 131, member A
FANCE Fanconi anemia, complementation group E
FBXL6 F-box and leucine-rich repeat protein 6
FBXO31 F-box protein 31
FEM1C fem-1 homolog c (C. elegans)
FGF23 fibroblast growth factor 23
FRK fyn-related Src family tyrosine kinase
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBAS glioblastoma amplified sequence
GBP2 guanylate binding protein 2, interferon-inducible
HIST1H2AJ histone cluster 1, H2aj
HLA-J major histocompatibility complex, class I, J (pseudogene)
HMHA1 histocompatibility (minor) HA-1
ICK intestinal cell (MAK-like) kinase
IL4R interleukin 4 receptor
IMPDH1 IMP (inosine 5'-monophosphate) dehydrogenase 1
KIAA0355 KIAA0355
KIF13B kinesin family member 13B
KIF3A kinesin family member 3A
LPXN leupaxin
LYPD3 LY6/PLAUR domain containing 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MAGI1 membrane associated guanylate kinase, WW and PDZ domain containing 1
MAN2C1 mannosidase, alpha, class 2C, member 1
MBNL3 muscleblind-like splicing regulator 3
NPIPB15 nuclear pore complex interacting protein family, member B15
NPIPB3 nuclear pore complex interacting protein family, member B3
NPY1R neuropeptide Y receptor Y1
NRGN neurogranin (protein kinase C substrate, RC3)
NUBPL nucleotide binding protein-like
NUP62CL nucleoporin 62kDa C-terminal like
PHACTR4 phosphatase and actin regulator 4
PHC1 polyhomeotic homolog 1 (Drosophila)
PMCH pro-melanin-concentrating hormone
PPOX protoporphyrinogen oxidase
PPP6R1 protein phosphatase 6, regulatory subunit 1
PROS1 protein S (alpha)
PRSS16 protease, serine, 16 (thymus)
RAB28 RAB28, member RAS oncogene family
RSF1 remodeling and spacing factor 1
SAV1 salvador family WW domain containing protein 1
SCUBE2 signal peptide, CUB domain, EGF-like 2
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SEZ6L2 seizure related 6 homolog (mouse)-like 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC22A14 solute carrier family 22, member 14
SLC2A6 solute carrier family 2 (facilitated glucose transporter), member 6
SNHG20 small nucleolar RNA host gene 20
SNIP1 Smad nuclear interacting protein 1
SP1 Sp1 transcription factor
SPIDR scaffolding protein involved in DNA repair
STRN striatin, calmodulin binding protein
SUN2 Sad1 and UNC84 domain containing 2
TDRD1 tudor domain containing 1
TNRC6B trinucleotide repeat containing 6B
TSPAN15 tetraspanin 15
TTBK2 tau tubulin kinase 2
TTC23 tetratricopeptide repeat domain 23
TUBA3C tubulin, alpha 3c
TUBGCP5 tubulin, gamma complex associated protein 5
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
USP27X ubiquitin specific peptidase 27, X-linked
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
XYLT2 xylosyltransferase II
ZFP30 ZFP30 zinc finger protein
ZMAT5 zinc finger, matrin-type 5
ZNF250 zinc finger protein 250
ZNF282 zinc finger protein 282
ZNF480 zinc finger protein 480
ZNF623 zinc finger protein 623
ZNF675 zinc finger protein 675
ZNRD1-AS1 ZNRD1 antisense RNA 1
ZSCAN26 zinc finger and SCAN domain containing 26
ZSCAN9 zinc finger and SCAN domain containing 9