sulfamonomethoxine-7200 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulfamonomethoxine-7200 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADAM10 ADAM metallopeptidase domain 10
ADAM17 ADAM metallopeptidase domain 17
ADTRP androgen-dependent TFPI-regulating protein
AKR1C2 aldo-keto reductase family 1, member C2
ANXA2P3 annexin A2 pseudogene 3
ARAP2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BAHD1 bromo adjacent homology domain containing 1
C10ORF88 chromosome 10 open reading frame 88
CA9 carbonic anhydrase IX
CABYR calcium binding tyrosine-(Y)-phosphorylation regulated
CACFD1 calcium channel flower domain containing 1
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CC2D1A coiled-coil and C2 domain containing 1A
CCDC186 coiled-coil domain containing 186
CCNO cyclin O
CCPG1 cell cycle progression 1
CDC14B cell division cycle 14B
CDKL3 cyclin-dependent kinase-like 3
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLASP2 cytoplasmic linker associated protein 2
CLDND1 claudin domain containing 1
CNNM2 cyclin and CBS domain divalent metal cation transport mediator 2
COPS8 COP9 signalosome subunit 8
CTNS cystinosin, lysosomal cystine transporter
DCTN1 dynactin 1
DOK4 docking protein 4
F2R coagulation factor II (thrombin) receptor
FLJ21369 uncharacterized protein FLJ21369
FLT4 fms-related tyrosine kinase 4
GIT2 G protein-coupled receptor kinase interacting ArfGAP 2
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPATCH2L G patch domain containing 2-like
HIST1H2BC histone cluster 1, H2bc
HPS1 Hermansky-Pudlak syndrome 1
HSD17B6 hydroxysteroid (17-beta) dehydrogenase 6
IFT122 intraflagellar transport 122
IL17RA interleukin 17 receptor A
INHBA inhibin, beta A
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
INTS6 integrator complex subunit 6
KCNK12 potassium channel, two pore domain subfamily K, member 12
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KRAS Kirsten rat sarcoma viral oncogene homolog
LGALS8 lectin, galactoside-binding, soluble, 8
LYPD1 LY6/PLAUR domain containing 1
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
MBNL2 muscleblind-like splicing regulator 2
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2
MSR1 macrophage scavenger receptor 1
MTMR6 myotubularin related protein 6
NDE1 nudE neurodevelopment protein 1
NFKBIE nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
NXT2 nuclear transport factor 2-like export factor 2
OVOL2 ovo-like zinc finger 2
PAOX polyamine oxidase (exo-N4-amino)
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PIBF1 progesterone immunomodulatory binding factor 1
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTDSS2 phosphatidylserine synthase 2
QKI QKI, KH domain containing, RNA binding
RCAN1 regulator of calcineurin 1
RCBTB1 regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
RGS2 regulator of G-protein signaling 2
RPS3A ribosomal protein S3A
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RTN2 reticulon 2
SDC2 syndecan 2
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SLC35A2 solute carrier family 35 (UDP-galactose transporter), member A2
SMG6 SMG6 nonsense mediated mRNA decay factor
SOCS1 suppressor of cytokine signaling 1
SOD2 superoxide dismutase 2, mitochondrial
SOX4 SRY (sex determining region Y)-box 4
SP100 SP100 nuclear antigen
SPRED2 sprouty-related, EVH1 domain containing 2
TEP1 telomerase-associated protein 1
TEX261 testis expressed 261
TGFB1I1 transforming growth factor beta 1 induced transcript 1
THAP1 THAP domain containing, apoptosis associated protein 1
THAP3 THAP domain containing, apoptosis associated protein 3
TMEM212 transmembrane protein 212
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRAF3IP2 TRAF3 interacting protein 2
TRPM4 transient receptor potential cation channel, subfamily M, member 4
TTBK2 tau tubulin kinase 2
TWF2 twinfilin actin binding protein 2
USP12 ubiquitin specific peptidase 12
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
ACVR2B activin A receptor, type IIB
AFAP1 actin filament associated protein 1
AKR1C3 aldo-keto reductase family 1, member C3
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ARSB arylsulfatase B
ASAP1-IT1 ASAP1 intronic transcript 1
BCL9 B-cell CLL/lymphoma 9
BMP4 bone morphogenetic protein 4
C11ORF68 chromosome 11 open reading frame 68
C14ORF132 chromosome 14 open reading frame 132
CAPN15 calpain 15
CCDC85C coiled-coil domain containing 85C
CFD complement factor D (adipsin)
CGA glycoprotein hormones, alpha polypeptide
CNR2 cannabinoid receptor 2 (macrophage)
CRABP1 cellular retinoic acid binding protein 1
CUEDC1 CUE domain containing 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DET1 de-etiolated homolog 1 (Arabidopsis)
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA2 EPH receptor A2
FLCN folliculin
FMO4 flavin containing monooxygenase 4
FSD1 fibronectin type III and SPRY domain containing 1
GAN gigaxonin
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLTSCR1 glioma tumor suppressor candidate region gene 1
GRB7 growth factor receptor-bound protein 7
GSTM2 glutathione S-transferase mu 2 (muscle)
GTF2A1 general transcription factor IIA, 1, 19/37kDa
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HIST1H2AI histone cluster 1, H2ai
HIST1H2AJ histone cluster 1, H2aj
IDI2-AS1 IDI2 antisense RNA 1
IPO8 importin 8
JMJD4 jumonji domain containing 4
KLK5 kallikrein-related peptidase 5
LGALS4 lectin, galactoside-binding, soluble, 4
LRP3 low density lipoprotein receptor-related protein 3
MANBA mannosidase, beta A, lysosomal
MAP1S microtubule-associated protein 1S
MAPKBP1 mitogen-activated protein kinase binding protein 1
MED15 mediator complex subunit 15
MTERF1 mitochondrial transcription termination factor 1
NDRG1 N-myc downstream regulated 1
NES nestin
NRGN neurogranin (protein kinase C substrate, RC3)
OAS3 2'-5'-oligoadenylate synthetase 3, 100kDa
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAIP2B poly(A) binding protein interacting protein 2B
PAQR6 progestin and adipoQ receptor family member VI
PARD6A par-6 family cell polarity regulator alpha
PCSK7 proprotein convertase subtilisin/kexin type 7
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PECR peroxisomal trans-2-enoyl-CoA reductase
PEX26 peroxisomal biogenesis factor 26
PGPEP1 pyroglutamyl-peptidase I
PHC3 polyhomeotic homolog 3 (Drosophila)
PICK1 protein interacting with PRKCA 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHO2 pleckstrin homology domain containing, family O member 2
POM121 POM121 transmembrane nucleoporin
PPP1R3C protein phosphatase 1, regulatory subunit 3C
PRICKLE3 prickle homolog 3 (Drosophila)
RPL7A ribosomal protein L7a
SCD5 stearoyl-CoA desaturase 5
SCN1B sodium channel, voltage gated, type I beta subunit
SDC3 syndecan 3
SETD1A SET domain containing 1A
SH2B2 SH2B adaptor protein 2
SLC22A14 solute carrier family 22, member 14
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SOWAHC sosondowah ankyrin repeat domain family member C
SPAG7 sperm associated antigen 7
SPIDR scaffolding protein involved in DNA repair
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SREK1IP1 SREK1-interacting protein 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
THBS3 thrombospondin 3
TICAM1 toll-like receptor adaptor molecule 1
TMEM180 transmembrane protein 180
TMEM53 transmembrane protein 53
TTC30A tetratricopeptide repeat domain 30A
UBQLN4 ubiquilin 4
UBTD1 ubiquitin domain containing 1
USP27X ubiquitin specific peptidase 27, X-linked
VPS9D1 VPS9 domain containing 1
WNT1 wingless-type MMTV integration site family, member 1
XK X-linked Kx blood group
ZC3H3 zinc finger CCCH-type containing 3
ZFP69B ZFP69 zinc finger protein B
ZNF212 zinc finger protein 212
ZNF250 zinc finger protein 250
ZNF324 zinc finger protein 324
ZNF701 zinc finger protein 701