sulfametoxydiazine-3453 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the sulfametoxydiazine-3453 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABHD6 abhydrolase domain containing 6
AMPD3 adenosine monophosphate deaminase 3
ANP32A-IT1 ANP32A intronic transcript 1
APOM apolipoprotein M
ARAP1 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
ASB1 ankyrin repeat and SOCS box containing 1
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BCL2L10 BCL2-like 10 (apoptosis facilitator)
CCHCR1 coiled-coil alpha-helical rod protein 1
CD248 CD248 molecule, endosialin
CDC14A cell division cycle 14A
CFAP69 cilia and flagella associated protein 69
CFLAR CASP8 and FADD-like apoptosis regulator
CHST8 carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8
CIDEC cell death-inducing DFFA-like effector c
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
CNTNAP2 contactin associated protein-like 2
COA1 cytochrome c oxidase assembly factor 1 homolog (S. cerevisiae)
COL1A1 collagen, type I, alpha 1
COL21A1 collagen, type XXI, alpha 1
CTNS cystinosin, lysosomal cystine transporter
CTSZ cathepsin Z
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
DCAKD dephospho-CoA kinase domain containing
DLG5 discs, large homolog 5 (Drosophila)
DOC2A double C2-like domains, alpha
ELOVL2 ELOVL fatty acid elongase 2
ENTPD4 ectonucleoside triphosphate diphosphohydrolase 4
F2R coagulation factor II (thrombin) receptor
FLJ11710 uncharacterized protein FLJ11710
FPGS folylpolyglutamate synthase
GM2A GM2 ganglioside activator
GPR137 G protein-coupled receptor 137
GPR153 G protein-coupled receptor 153
GRM1 glutamate receptor, metabotropic 1
HFE hemochromatosis
HOXA9 homeobox A9
HSPG2 heparan sulfate proteoglycan 2
IFNAR1 interferon (alpha, beta and omega) receptor 1
IL11 interleukin 11
IL1A interleukin 1, alpha
ITGB5 integrin, beta 5
KCNA3 potassium channel, voltage gated shaker related subfamily A, member 3
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KLHL25 kelch-like family member 25
KRBOX4 KRAB box domain containing 4
LDHC lactate dehydrogenase C
MARCKS myristoylated alanine-rich protein kinase C substrate
MBOAT7 membrane bound O-acyltransferase domain containing 7
MED18 mediator complex subunit 18
METTL7A methyltransferase like 7A
MFGE8 milk fat globule-EGF factor 8 protein
MSI1 musashi RNA-binding protein 1
NCOA2 nuclear receptor coactivator 2
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
PARG poly (ADP-ribose) glycohydrolase
PCDHB6 protocadherin beta 6
PDAP1 PDGFA associated protein 1
PKNOX1 PBX/knotted 1 homeobox 1
PLLP plasmolipin
PODNL1 podocan-like 1
PPIA peptidylprolyl isomerase A (cyclophilin A)
PSMB2 proteasome (prosome, macropain) subunit, beta type, 2
PTPN14 protein tyrosine phosphatase, non-receptor type 14
PVR poliovirus receptor
RABEP2 rabaptin, RAB GTPase binding effector protein 2
RANBP1 RAN binding protein 1
RARA retinoic acid receptor, alpha
RASAL2 RAS protein activator like 2
RB1 retinoblastoma 1
REEP1 receptor accessory protein 1
RHEB Ras homolog enriched in brain
RIN1 Ras and Rab interactor 1
RND1 Rho family GTPase 1
RP2 retinitis pigmentosa 2 (X-linked recessive)
RPL23AP32 ribosomal protein L23a pseudogene 32
SH3BP2 SH3-domain binding protein 2
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC24A3 solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
SRD5A3 steroid 5 alpha-reductase 3
ST3GAL2 ST3 beta-galactoside alpha-2,3-sialyltransferase 2
SYNGR1 synaptogyrin 1
TOP3A topoisomerase (DNA) III alpha
TSC22D2 TSC22 domain family, member 2
TUBA3C tubulin, alpha 3c
TUBBP5 tubulin, beta pseudogene 5
USB1 U6 snRNA biogenesis 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WDR62 WD repeat domain 62
WSB1 WD repeat and SOCS box containing 1
ZFP36L2 ZFP36 ring finger protein-like 2
ZHX3 zinc fingers and homeoboxes 3
ZNF3 zinc finger protein 3
ZNF350 zinc finger protein 350
ZNF428 zinc finger protein 428
ZNF43 zinc finger protein 43
ZNF574 zinc finger protein 574
ZNF652 zinc finger protein 652

decreased expression

Symbol Name
ABCA12 ATP-binding cassette, sub-family A (ABC1), member 12
ACTL8 actin-like 8
ADM adrenomedullin
ANXA1 annexin A1
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
ATAD5 ATPase family, AAA domain containing 5
ATG9A autophagy related 9A
BAG4 BCL2-associated athanogene 4
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BCL2L2 BCL2-like 2
C5AR2 complement component 5a receptor 2
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASZ1 castor zinc finger 1
CCDC85C coiled-coil domain containing 85C
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CEP97 centrosomal protein 97kDa
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CIR1 corepressor interacting with RBPJ, 1
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLSPN claspin
COL9A2 collagen, type IX, alpha 2
CORT cortistatin
CRYBB2P1 crystallin, beta B2 pseudogene 1
DDIT3 DNA-damage-inducible transcript 3
DNAJC22 DnaJ (Hsp40) homolog, subfamily C, member 22
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EGLN3 egl-9 family hypoxia-inducible factor 3
EML4 echinoderm microtubule associated protein like 4
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPPK1 epiplakin 1
ETS2 v-ets avian erythroblastosis virus E26 oncogene homolog 2
F3 coagulation factor III (thromboplastin, tissue factor)
FBXL6 F-box and leucine-rich repeat protein 6
FBXO22 F-box protein 22
FER fer (fps/fes related) tyrosine kinase
FOCAD focadhesin
FRAT1 frequently rearranged in advanced T-cell lymphomas 1
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
GPR143 G protein-coupled receptor 143
HIST1H2BJ histone cluster 1, H2bj
HMHA1 histocompatibility (minor) HA-1
HOXC11 homeobox C11
IFT81 intraflagellar transport 81
IPO8 importin 8
ISG20 interferon stimulated exonuclease gene 20kDa
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
KDM5C lysine (K)-specific demethylase 5C
KIAA0430 KIAA0430
LHPP phospholysine phosphohistidine inorganic pyrophosphate phosphatase
LOC730101 uncharacterized LOC730101
LRIG1 leucine-rich repeats and immunoglobulin-like domains 1
LYPD3 LY6/PLAUR domain containing 3
LZTS3 leucine zipper, putative tumor suppressor family member 3
MON1B MON1 secretory trafficking family member B
NECAB3 N-terminal EF-hand calcium binding protein 3
NR1H3 nuclear receptor subfamily 1, group H, member 3
NUP62CL nucleoporin 62kDa C-terminal like
OR7E156P olfactory receptor, family 7, subfamily E, member 156 pseudogene
OXTR oxytocin receptor
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PGS1 phosphatidylglycerophosphate synthase 1
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PLA2G3 phospholipase A2, group III
RGS19 regulator of G-protein signaling 19
RPAP2 RNA polymerase II associated protein 2
RPL13P5 ribosomal protein L13 pseudogene 5
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SERPINF1 serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
SKA1 spindle and kinetochore associated complex subunit 1
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC2A10 solute carrier family 2 (facilitated glucose transporter), member 10
SLC35C1 solute carrier family 35 (GDP-fucose transporter), member C1
SOX12 SRY (sex determining region Y)-box 12
SPATA2L spermatogenesis associated 2-like
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
TARP TCR gamma alternate reading frame protein
TET3 tet methylcytosine dioxygenase 3
TINF2 TERF1 (TRF1)-interacting nuclear factor 2
TM7SF3 transmembrane 7 superfamily member 3
TMEM115 transmembrane protein 115
TNKS2 tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSPYL2 TSPY-like 2
TUBG2 tubulin, gamma 2
TUT1 terminal uridylyl transferase 1, U6 snRNA-specific
UBQLN4 ubiquilin 4
WDR33 WD repeat domain 33
XAB2 XPA binding protein 2
ZFHX3 zinc finger homeobox 3
ZNF480 zinc finger protein 480
ZNF573 zinc finger protein 573
ZNF747 zinc finger protein 747