sulfamethoxazole-7366 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfamethoxazole-7366 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACOX3 acyl-CoA oxidase 3, pristanoyl
AMT aminomethyltransferase
ARL14 ADP-ribosylation factor-like 14
ATP2C2 ATPase, Ca++ transporting, type 2C, member 2
BNC1 basonuclin 1
BTRC beta-transducin repeat containing E3 ubiquitin protein ligase
CCPG1 cell cycle progression 1
CDC25C cell division cycle 25C
CDC42BPA CDC42 binding protein kinase alpha (DMPK-like)
CES2 carboxylesterase 2
CFLAR CASP8 and FADD-like apoptosis regulator
CHRM3 cholinergic receptor, muscarinic 3
CISH cytokine inducible SH2-containing protein
CLCN6 chloride channel, voltage-sensitive 6
CYBRD1 cytochrome b reductase 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1
DARS2 aspartyl-tRNA synthetase 2, mitochondrial
DCAF11 DDB1 and CUL4 associated factor 11
DDN dendrin
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DFNB31 deafness, autosomal recessive 31
DNAJB5 DnaJ (Hsp40) homolog, subfamily B, member 5
DST dystonin
EDRF1 erythroid differentiation regulatory factor 1
EFNA3 ephrin-A3
EGFR epidermal growth factor receptor
EPB41L5 erythrocyte membrane protein band 4.1 like 5
FAM13A family with sequence similarity 13, member A
FAM184A family with sequence similarity 184, member A
FBN2 fibrillin 2
FBXO11 F-box protein 11
FKBP8 FK506 binding protein 8, 38kDa
FZD1 frizzled class receptor 1
GATA2 GATA binding protein 2
GGA2 golgi-associated, gamma adaptin ear containing, ARF binding protein 2
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPATCH2L G patch domain containing 2-like
GSAP gamma-secretase activating protein
GUSBP3 glucuronidase, beta pseudogene 3
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HNRNPM heterogeneous nuclear ribonucleoprotein M
HOXA1 homeobox A1
HOXB5 homeobox B5
IRF4 interferon regulatory factor 4
ITGB4 integrin, beta 4
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCNAB2 potassium channel, voltage gated subfamily A regulatory beta subunit 2
KIF5C kinesin family member 5C
KRT34 keratin 34, type I
LARP4B La ribonucleoprotein domain family, member 4B
LEF1 lymphoid enhancer-binding factor 1
LIMK2 LIM domain kinase 2
LPIN1 lipin 1
MARK4 MAP/microtubule affinity-regulating kinase 4
MDFIC MyoD family inhibitor domain containing
MMRN2 multimerin 2
MTCP1 mature T-cell proliferation 1
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NUP214 nucleoporin 214kDa
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PDK3 pyruvate dehydrogenase kinase, isozyme 3
PER1 period circadian clock 1
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PLEKHO2 pleckstrin homology domain containing, family O member 2
PMS2P3 postmeiotic segregation increased 2 pseudogene 3
POMT2 protein-O-mannosyltransferase 2
PRF1 perforin 1 (pore forming protein)
PRKAR1B protein kinase, cAMP-dependent, regulatory, type I, beta
PRSS53 protease, serine, 53
PTCH1 patched 1
PTH1R parathyroid hormone 1 receptor
RAD52 RAD52 homolog (S. cerevisiae)
RGS10 regulator of G-protein signaling 10
SAPCD1 suppressor APC domain containing 1
SELPLG selectin P ligand
SFTPC surfactant protein C
SGSM3 small G protein signaling modulator 3
SHROOM2 shroom family member 2
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SOS2 son of sevenless homolog 2 (Drosophila)
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TBCD tubulin folding cofactor D
TECPR2 tectonin beta-propeller repeat containing 2
TFAP2C transcription factor AP-2 gamma (activating enhancer binding protein 2 gamma)
TINAGL1 tubulointerstitial nephritis antigen-like 1
TNK1 tyrosine kinase, non-receptor, 1
TXNIP thioredoxin interacting protein
UBE3B ubiquitin protein ligase E3B
XDH xanthine dehydrogenase
ZBTB20 zinc finger and BTB domain containing 20
ZER1 zyg-11 related, cell cycle regulator
ZKSCAN5 zinc finger with KRAB and SCAN domains 5
ZNF236 zinc finger protein 236
ZNF277 zinc finger protein 277
ZNF37BP zinc finger protein 37B, pseudogene
ZNF768 zinc finger protein 768

decreased expression

Symbol Name
AHDC1 AT hook, DNA binding motif, containing 1
ALPK1 alpha-kinase 1
ANXA2P1 annexin A2 pseudogene 1
ARAP3 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
ARHGEF26 Rho guanine nucleotide exchange factor (GEF) 26
ARMC6 armadillo repeat containing 6
BRAF B-Raf proto-oncogene, serine/threonine kinase
BRPF1 bromodomain and PHD finger containing, 1
C17ORF80 chromosome 17 open reading frame 80
C1QTNF1 C1q and tumor necrosis factor related protein 1
CAPN15 calpain 15
CAPN5 calpain 5
CCNO cyclin O
CDH7 cadherin 7, type 2
CDK3 cyclin-dependent kinase 3
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDON cell adhesion associated, oncogene regulated
CFAP44 cilia and flagella associated protein 44
CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2
CLEC10A C-type lectin domain family 10, member A
CLUH clustered mitochondria (cluA/CLU1) homolog
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CUL9 cullin 9
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
CXCL3 chemokine (C-X-C motif) ligand 3
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DOCK1 dedicator of cytokinesis 1
DSPP dentin sialophosphoprotein
ECM1 extracellular matrix protein 1
EPHA4 EPH receptor A4
ERN2 endoplasmic reticulum to nucleus signaling 2
FLCN folliculin
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLDC glycine dehydrogenase (decarboxylating)
GOLGA1 golgin A1
GRAMD4 GRAM domain containing 4
GRWD1 glutamate-rich WD repeat containing 1
HIST1H2AI histone cluster 1, H2ai
HIST1H2AM histone cluster 1, H2am
HIST1H3A histone cluster 1, H3a
HIST1H3B histone cluster 1, H3b
HIST1H3G histone cluster 1, H3g
HPS6 Hermansky-Pudlak syndrome 6
INPPL1 inositol polyphosphate phosphatase-like 1
KCNN4 potassium channel, calcium activated intermediate/small conductance subfamily N alpha, member 4
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAP1S microtubule-associated protein 1S
MAST3 microtubule associated serine/threonine kinase 3
MCM9 minichromosome maintenance complex component 9
MEIS1 Meis homeobox 1
MMP1 matrix metallopeptidase 1
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3)
MXD3 MAX dimerization protein 3
MYBBP1A MYB binding protein (P160) 1a
MYL5 myosin, light chain 5, regulatory
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBEAL2 neurobeachin-like 2
NFIX nuclear factor I/X (CCAAT-binding transcription factor)
NUDT1 nudix (nucleoside diphosphate linked moiety X)-type motif 1
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
PAQR4 progestin and adipoQ receptor family member IV
PIP4K2B phosphatidylinositol-5-phosphate 4-kinase, type II, beta
RELB v-rel avian reticuloendotheliosis viral oncogene homolog B
RIN1 Ras and Rab interactor 1
RNF31 ring finger protein 31
RPP25 ribonuclease P/MRP 25kDa subunit
S100A3 S100 calcium binding protein A3
SH3GL2 SH3-domain GRB2-like 2
SIX1 SIX homeobox 1
SKIV2L superkiller viralicidic activity 2-like (S. cerevisiae)
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SNPH syntaphilin
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SUGCT succinyl-CoA:glutarate-CoA transferase
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TCF7L1 transcription factor 7-like 1 (T-cell specific, HMG-box)
TEP1 telomerase-associated protein 1
TMEM132A transmembrane protein 132A
TMEM177 transmembrane protein 177
TMEM2 transmembrane protein 2
TMEM209 transmembrane protein 209
TMEM212 transmembrane protein 212
TMEM8B transmembrane protein 8B
TNNI3 troponin I type 3 (cardiac)
TPCN1 two pore segment channel 1
TRABD TraB domain containing
TRAIP TRAF interacting protein
TSC22D4 TSC22 domain family, member 4
ULBP2 UL16 binding protein 2
USP6 ubiquitin specific peptidase 6
WDR18 WD repeat domain 18
WDR91 WD repeat domain 91
WNT7A wingless-type MMTV integration site family, member 7A
ZNF629 zinc finger protein 629