sulfamethizole-6272 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

199 genes differentially expressed following the sulfamethizole-6272 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ACADSB acyl-CoA dehydrogenase, short/branched chain
ADAM22 ADAM metallopeptidase domain 22
ADAM5 ADAM metallopeptidase domain 5 (pseudogene)
ADH1A alcohol dehydrogenase 1A (class I), alpha polypeptide
ALMS1 Alstrom syndrome protein 1
ANGPT1 angiopoietin 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL3 ADP-ribosylation factor-like 3
ARR3 arrestin 3, retinal (X-arrestin)
ARVCF armadillo repeat gene deleted in velocardiofacial syndrome
ASPH aspartate beta-hydroxylase
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2
ATRX alpha thalassemia/mental retardation syndrome X-linked
AVL9 AVL9 homolog (S. cerevisiase)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
B3GNTL1 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase-like 1
BAIAP3 BAI1-associated protein 3
BRS3 bombesin-like receptor 3
C1QTNF1 C1q and tumor necrosis factor related protein 1
CALD1 caldesmon 1
CALHM2 calcium homeostasis modulator 2
CEACAM6 carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen)
CLCN7 chloride channel, voltage-sensitive 7
CLN5 ceroid-lipofuscinosis, neuronal 5
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
DIO2 deiodinase, iodothyronine, type II
DLC1 DLC1 Rho GTPase activating protein
DTX2P1-UPK3BP1-PMS2P11 DTX2P1-UPK3BP1-PMS2P11 readthrough transcribed pseudogene
DVL3 dishevelled segment polarity protein 3
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
FAM169A family with sequence similarity 169, member A
FBXO9 F-box protein 9
FGFR1 fibroblast growth factor receptor 1
FN1 fibronectin 1
FNTB farnesyltransferase, CAAX box, beta
GK glycerol kinase
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide
HEXA hexosaminidase A (alpha polypeptide)
HIST1H2AJ histone cluster 1, H2aj
HOMER3 homer scaffolding protein 3
IL6ST interleukin 6 signal transducer
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNQ3 potassium channel, voltage gated KQT-like subfamily Q, member 3
KIAA0930 KIAA0930
LRRC41 leucine rich repeat containing 41
LRRC61 leucine rich repeat containing 61
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
MAP2K5 mitogen-activated protein kinase kinase 5
MAP2K7 mitogen-activated protein kinase kinase 7
MAP4 microtubule-associated protein 4
MECP2 methyl CpG binding protein 2
MFAP2 microfibrillar-associated protein 2
MMP2 matrix metallopeptidase 2
MRPL41 mitochondrial ribosomal protein L41
MST1 macrophage stimulating 1
NCAPH2 non-SMC condensin II complex, subunit H2
NDUFB8 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 8, 19kDa
NMT2 N-myristoyltransferase 2
NPPA natriuretic peptide A
NRSN2 neurensin 2
OMG oligodendrocyte myelin glycoprotein
ONECUT2 one cut homeobox 2
OR1D2 olfactory receptor, family 1, subfamily D, member 2
OSBPL7 oxysterol binding protein-like 7
OSGIN2 oxidative stress induced growth inhibitor family member 2
PCDHA3 protocadherin alpha 3
PDE5A phosphodiesterase 5A, cGMP-specific
PDGFD platelet derived growth factor D
PKD1 polycystic kidney disease 1 (autosomal dominant)
PLCB1 phospholipase C, beta 1 (phosphoinositide-specific)
POLG polymerase (DNA directed), gamma
PPP2R3A protein phosphatase 2, regulatory subunit B'', alpha
RBM8A RNA binding motif protein 8A
RCAN1 regulator of calcineurin 1
RIF1 replication timing regulatory factor 1
RNF122 ring finger protein 122
RNF19B ring finger protein 19B
S100A13 S100 calcium binding protein A13
SBNO2 strawberry notch homolog 2 (Drosophila)
SCAPER S-phase cyclin A-associated protein in the ER
SCG2 secretogranin II
SKA1 spindle and kinetochore associated complex subunit 1
SLC15A2 solute carrier family 15 (oligopeptide transporter), member 2
SLC43A3 solute carrier family 43, member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPHK2 sphingosine kinase 2
SPPL2B signal peptide peptidase like 2B
SUGP1 SURP and G patch domain containing 1
TBCD tubulin folding cofactor D
TFR2 transferrin receptor 2
TRABD TraB domain containing
TRIM5 tripartite motif containing 5
TSC22D3 TSC22 domain family, member 3
TTLL5 tubulin tyrosine ligase-like family member 5
TTLL7 tubulin tyrosine ligase-like family member 7
WDR62 WD repeat domain 62
ZNF324 zinc finger protein 324
ZNF573 zinc finger protein 573

decreased expression

Symbol Name
AHCTF1 AT hook containing transcription factor 1
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ARHGAP11A Rho GTPase activating protein 11A
ATP11B ATPase, class VI, type 11B
AXIN1 axin 1
BBS7 Bardet-Biedl syndrome 7
C11ORF80 chromosome 11 open reading frame 80
C5 complement component 5
C6ORF47 chromosome 6 open reading frame 47
CBX4 chromobox homolog 4
CCDC88C coiled-coil domain containing 88C
CDK5RAP2 CDK5 regulatory subunit associated protein 2
CDKL3 cyclin-dependent kinase-like 3
CFD complement factor D (adipsin)
CHCHD3 coiled-coil-helix-coiled-coil-helix domain containing 3
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11
CLASP1 cytoplasmic linker associated protein 1
CLCN5 chloride channel, voltage-sensitive 5
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
CORO1A coronin, actin binding protein, 1A
CPSF3L cleavage and polyadenylation specific factor 3-like
DBR1 debranching RNA lariats 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
EFCAB2 EF-hand calcium binding domain 2
EGLN3 egl-9 family hypoxia-inducible factor 3
ELOVL4 ELOVL fatty acid elongase 4
ERCC5 excision repair cross-complementation group 5
EVPL envoplakin
EXOC5 exocyst complex component 5
FBXO46 F-box protein 46
FGD6 FYVE, RhoGEF and PH domain containing 6
FKBP10 FK506 binding protein 10, 65 kDa
FKBP5 FK506 binding protein 5
FUZ fuzzy planar cell polarity protein
GADD45G growth arrest and DNA-damage-inducible, gamma
GCA grancalcin, EF-hand calcium binding protein
GCC2 GRIP and coiled-coil domain containing 2
GFOD1 glucose-fructose oxidoreductase domain containing 1
GLCE glucuronic acid epimerase
GLTSCR1 glioma tumor suppressor candidate region gene 1
GNG4 guanine nucleotide binding protein (G protein), gamma 4
HIST1H1D histone cluster 1, H1d
HIVEP1 human immunodeficiency virus type I enhancer binding protein 1
HOXC11 homeobox C11
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
IMPACT impact RWD domain protein
INPP5A inositol polyphosphate-5-phosphatase, 40kDa
INSIG2 insulin induced gene 2
IRF6 interferon regulatory factor 6
KBTBD4 kelch repeat and BTB (POZ) domain containing 4
L2HGDH L-2-hydroxyglutarate dehydrogenase
LZTR1 leucine-zipper-like transcription regulator 1
MAP3K14 mitogen-activated protein kinase kinase kinase 14
MDN1 MDN1, midasin homolog (yeast)
METTL16 methyltransferase like 16
METTL2B methyltransferase like 2B
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NOTCH1 notch 1
OCEL1 occludin/ELL domain containing 1
PARD6A par-6 family cell polarity regulator alpha
PBLD phenazine biosynthesis-like protein domain containing
PIGA phosphatidylinositol glycan anchor biosynthesis, class A
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
POTEKP POTE ankyrin domain family, member K, pseudogene
PYCRL pyrroline-5-carboxylate reductase-like
QTRT1 queuine tRNA-ribosyltransferase 1
RIPK1 receptor (TNFRSF)-interacting serine-threonine kinase 1
RPL13P5 ribosomal protein L13 pseudogene 5
RWDD3 RWD domain containing 3
SCGB2A2 secretoglobin, family 2A, member 2
SETD8 SET domain containing (lysine methyltransferase) 8
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC16A6 solute carrier family 16, member 6
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC35E3 solute carrier family 35, member E3
SLC46A3 solute carrier family 46, member 3
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TBC1D31 TBC1 domain family, member 31
TDRD7 tudor domain containing 7
THOP1 thimet oligopeptidase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TM7SF3 transmembrane 7 superfamily member 3
TMED7 transmembrane emp24 protein transport domain containing 7
TMEM180 transmembrane protein 180
TNRC6B trinucleotide repeat containing 6B
TPST2 tyrosylprotein sulfotransferase 2
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TRMU tRNA 5-methylaminomethyl-2-thiouridylate methyltransferase
TTC23 tetratricopeptide repeat domain 23
TUBA3C tubulin, alpha 3c
UBE2L6 ubiquitin-conjugating enzyme E2L 6
UBXN2B UBX domain protein 2B
WLS wntless Wnt ligand secretion mediator
XAB2 XPA binding protein 2
ZDHHC4 zinc finger, DHHC-type containing 4
ZNF248 zinc finger protein 248
ZNF280D zinc finger protein 280D
ZNF552 zinc finger protein 552