sulfamerazine-6036 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfamerazine-6036 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADGRA2 adhesion G protein-coupled receptor A2
AFF2 AF4/FMR2 family, member 2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ALDH7A1 aldehyde dehydrogenase 7 family, member A1
APOE apolipoprotein E
ASIC3 acid sensing (proton gated) ion channel 3
BHMT betaine--homocysteine S-methyltransferase
BTF3P11 basic transcription factor 3 pseudogene 11
C1QTNF1 C1q and tumor necrosis factor related protein 1
C7ORF69 chromosome 7 open reading frame 69
C8A complement component 8, alpha polypeptide
CALD1 caldesmon 1
CCRL2 chemokine (C-C motif) receptor-like 2
CD209 CD209 molecule
CD40 CD40 molecule, TNF receptor superfamily member 5
CDC14A cell division cycle 14A
CDH6 cadherin 6, type 2, K-cadherin (fetal kidney)
CDHR2 cadherin-related family member 2
CHST5 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 5
CNR1 cannabinoid receptor 1 (brain)
CSHL1 chorionic somatomammotropin hormone-like 1
CXCL8 chemokine (C-X-C motif) ligand 8
CYP24A1 cytochrome P450, family 24, subfamily A, polypeptide 1
DGKQ diacylglycerol kinase, theta 110kDa
DNAI2 dynein, axonemal, intermediate chain 2
FGF6 fibroblast growth factor 6
FHL1 four and a half LIM domains 1
FLRT2 fibronectin leucine rich transmembrane protein 2
FRAS1 Fraser extracellular matrix complex subunit 1
GPR3 G protein-coupled receptor 3
GRM8 glutamate receptor, metabotropic 8
HAS2 hyaluronan synthase 2
HES2 hes family bHLH transcription factor 2
HR hair growth associated
HTR1D 5-hydroxytryptamine (serotonin) receptor 1D, G protein-coupled
IGFBP3 insulin-like growth factor binding protein 3
INS insulin
KCNAB1 potassium channel, voltage gated subfamily A regulatory beta subunit 1
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRT14 keratin 14, type I
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MED25 mediator complex subunit 25
MGAM maltase-glucoamylase
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4
MSC musculin
MYOC myocilin, trabecular meshwork inducible glucocorticoid response
NAG18 NAG18 mRNA
NCR2 natural cytotoxicity triggering receptor 2
NPHS2 nephrosis 2, idiopathic, steroid-resistant (podocin)
OCA2 oculocutaneous albinism II
OR10H3 olfactory receptor, family 10, subfamily H, member 3
PAX2 paired box 2
PDE12 phosphodiesterase 12
PDGFRA platelet-derived growth factor receptor, alpha polypeptide
PEAK1 pseudopodium-enriched atypical kinase 1
PLCE1 phospholipase C, epsilon 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLG plasminogen
PRB1 proline-rich protein BstNI subfamily 1
PRSS21 protease, serine, 21 (testisin)
PRSS50 protease, serine, 50
PTGER3 prostaglandin E receptor 3 (subtype EP3)
PURA purine-rich element binding protein A
RAB3B RAB3B, member RAS oncogene family
RGS14 regulator of G-protein signaling 14
RNF126P1 ring finger protein 126 pseudogene 1
RPL35A ribosomal protein L35a
RRH retinal pigment epithelium-derived rhodopsin homolog
RTN2 reticulon 2
SAMD9 sterile alpha motif domain containing 9
SERHL2 serine hydrolase-like 2
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC22A7 solute carrier family 22 (organic anion transporter), member 7
SLC35G2 solute carrier family 35, member G2
SNPH syntaphilin
SNRPN small nuclear ribonucleoprotein polypeptide N
SOCS3 suppressor of cytokine signaling 3
SOGA1 suppressor of glucose, autophagy associated 1
SPATA1 spermatogenesis associated 1
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
STC1 stanniocalcin 1
SULT4A1 sulfotransferase family 4A, member 1
SUPT20H suppressor of Ty 20 homolog (S. cerevisiae)
SVIL supervillin
SYMPK symplekin
TIMM8A translocase of inner mitochondrial membrane 8 homolog A (yeast)
TJAP1 tight junction associated protein 1 (peripheral)
TPMT thiopurine S-methyltransferase
TRH thyrotropin-releasing hormone
TSSK2 testis-specific serine kinase 2
USP22 ubiquitin specific peptidase 22
VAV2 vav 2 guanine nucleotide exchange factor
ZFP2 ZFP2 zinc finger protein
ZNF440 zinc finger protein 440
ZNF528 zinc finger protein 528
ZNF711 zinc finger protein 711

decreased expression

Symbol Name
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5
ADM adrenomedullin
ANKRA2 ankyrin repeat, family A (RFXANK-like), 2
APOD apolipoprotein D
APOLD1 apolipoprotein L domain containing 1
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARRB1 arrestin, beta 1
B9D2 B9 protein domain 2
C11ORF95 chromosome 11 open reading frame 95
C21ORF91 chromosome 21 open reading frame 91
C5ORF28 chromosome 5 open reading frame 28
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CCDC88C coiled-coil domain containing 88C
CDK20 cyclin-dependent kinase 20
COCH cochlin
COPZ2 coatomer protein complex, subunit zeta 2
CSF1R colony stimulating factor 1 receptor
CST6 cystatin E/M
CUZD1 CUB and zona pellucida-like domains 1
CWF19L1 CWF19-like 1, cell cycle control (S. pombe)
DMC1 DNA meiotic recombinase 1
DNAJB2 DnaJ (Hsp40) homolog, subfamily B, member 2
DUSP2 dual specificity phosphatase 2
EGR3 early growth response 3
EHMT1 euchromatic histone-lysine N-methyltransferase 1
ENO2 enolase 2 (gamma, neuronal)
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EVA1B eva-1 homolog B (C. elegans)
FAM155B family with sequence similarity 155, member B
FAM204A family with sequence similarity 204, member A
FBXL15 F-box and leucine-rich repeat protein 15
FBXL6 F-box and leucine-rich repeat protein 6
FBXO31 F-box protein 31
FLVCR2 feline leukemia virus subgroup C cellular receptor family, member 2
FOXN2 forkhead box N2
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
IDI2-AS1 IDI2 antisense RNA 1
INO80D INO80 complex subunit D
IRF2 interferon regulatory factor 2
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRF6 interferon regulatory factor 6
KCNMB3 potassium channel subfamily M regulatory beta subunit 3
LAMA3 laminin, alpha 3
LGR4 leucine-rich repeat containing G protein-coupled receptor 4
LMO2 LIM domain only 2 (rhombotin-like 1)
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LRP5L low density lipoprotein receptor-related protein 5-like
LRRC20 leucine rich repeat containing 20
MCOLN1 mucolipin 1
MEIS2 Meis homeobox 2
METTL4 methyltransferase like 4
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MNS1 meiosis-specific nuclear structural 1
NME7 NME/NM23 family member 7
NOL12 nucleolar protein 12
NPIPB3 nuclear pore complex interacting protein family, member B3
NUS1P3 nuclear undecaprenyl pyrophosphate synthase 1 homolog (S. cerevisiae) pseudogene 3
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PACS1 phosphofurin acidic cluster sorting protein 1
PADI2 peptidyl arginine deiminase, type II
PCDHA9 protocadherin alpha 9
PCDHB3 protocadherin beta 3
PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1
POLL polymerase (DNA directed), lambda
QSER1 glutamine and serine rich 1
RAD51B RAD51 paralog B
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RBL1 retinoblastoma-like 1
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RNF122 ring finger protein 122
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SKA1 spindle and kinetochore associated complex subunit 1
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC25A21 solute carrier family 25 (mitochondrial oxoadipate carrier), member 21
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STRA6 stimulated by retinoic acid 6
STRN striatin, calmodulin binding protein
SYCP2 synaptonemal complex protein 2
SYNGR3 synaptogyrin 3
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1
TBL3 transducin (beta)-like 3
TPST2 tyrosylprotein sulfotransferase 2
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
USP19 ubiquitin specific peptidase 19
USP27X ubiquitin specific peptidase 27, X-linked
VASH2 vasohibin 2
ZBTB24 zinc finger and BTB domain containing 24
ZBTB6 zinc finger and BTB domain containing 6
ZNF189 zinc finger protein 189
ZNF219 zinc finger protein 219
ZNF273 zinc finger protein 273
ZNF286A zinc finger protein 286A
ZNF34 zinc finger protein 34
ZNF767P zinc finger family member 767, pseudogene
ZNF83 zinc finger protein 83