sulfamerazine-2181 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

196 genes differentially expressed following the sulfamerazine-2181 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACYP1 acylphosphatase 1, erythrocyte (common) type
AKAP13 A kinase (PRKA) anchor protein 13
ALDOB aldolase B, fructose-bisphosphate
ANGEL2 angel homolog 2 (Drosophila)
ATP9B ATPase, class II, type 9B
BIRC3 baculoviral IAP repeat containing 3
BMP1 bone morphogenetic protein 1
BRF1 BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
CAT catalase
CBX8 chromobox homolog 8
CD22 CD22 molecule
CD79A CD79a molecule, immunoglobulin-associated alpha
CD84 CD84 molecule
CDK5R1 cyclin-dependent kinase 5, regulatory subunit 1 (p35)
CFAP70 cilia and flagella associated protein 70
CLTA clathrin, light chain A
CMTR1 cap methyltransferase 1
COLQ collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
COPG2IT1 COPG2 imprinted transcript 1 (non-protein coding)
CTSZ cathepsin Z
CUBN cubilin (intrinsic factor-cobalamin receptor)
CYP4F12 cytochrome P450, family 4, subfamily F, polypeptide 12
DHRS7 dehydrogenase/reductase (SDR family) member 7
DLGAP4 discs, large (Drosophila) homolog-associated protein 4
DOK5 docking protein 5
DSPP dentin sialophosphoprotein
DTX2 deltex 2, E3 ubiquitin ligase
EDRF1 erythroid differentiation regulatory factor 1
EML2 echinoderm microtubule associated protein like 2
FAM171A1 family with sequence similarity 171, member A1
FGFBP1 fibroblast growth factor binding protein 1
FMO5 flavin containing monooxygenase 5
FOXG1 forkhead box G1
FZD3 frizzled class receptor 3
GAS6 growth arrest-specific 6
GCFC2 GC-rich sequence DNA-binding factor 2
GGA3 golgi-associated, gamma adaptin ear containing, ARF binding protein 3
GLRA1 glycine receptor, alpha 1
GPLD1 glycosylphosphatidylinositol specific phospholipase D1
GRIP2 glutamate receptor interacting protein 2
HFE hemochromatosis
HOXA10 homeobox A10
IDH3G isocitrate dehydrogenase 3 (NAD+) gamma
IDS iduronate 2-sulfatase
IQCG IQ motif containing G
KCTD17 potassium channel tetramerization domain containing 17
KIAA0040 KIAA0040
KIF5A kinesin family member 5A
LAMP1 lysosomal-associated membrane protein 1
LMF1 lipase maturation factor 1
MAGOH2P mago-nashi homolog 2, pseudogene
MAL mal, T-cell differentiation protein
MBL1P mannose-binding lectin (protein A) 1, pseudogene
MID2 midline 2
MUC8 mucin 8
MYH14 myosin, heavy chain 14, non-muscle
NR6A1 nuclear receptor subfamily 6, group A, member 1
NUDT7 nudix (nucleoside diphosphate linked moiety X)-type motif 7
PAIP2B poly(A) binding protein interacting protein 2B
PAX2 paired box 2
PDGFRL platelet-derived growth factor receptor-like
PDLIM5 PDZ and LIM domain 5
PGAP3 post-GPI attachment to proteins 3
PKD1 polycystic kidney disease 1 (autosomal dominant)
POFUT1 protein O-fucosyltransferase 1
PPP1R12B protein phosphatase 1, regulatory subunit 12B
PRDX2 peroxiredoxin 2
PRODH2 proline dehydrogenase (oxidase) 2
RBMS3 RNA binding motif, single stranded interacting protein 3
RGS12 regulator of G-protein signaling 12
RHAG Rh-associated glycoprotein
RHOD ras homolog family member D
RPL23AP32 ribosomal protein L23a pseudogene 32
RQCD1 RCD1 required for cell differentiation1 homolog (S. pombe)
RTEL1 regulator of telomere elongation helicase 1
SCN11A sodium channel, voltage gated, type XI alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SIPA1L1 signal-induced proliferation-associated 1 like 1
SIRPA signal-regulatory protein alpha
SLC16A4 solute carrier family 16, member 4
SLC25A23 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 23
SLC45A2 solute carrier family 45, member 2
SNCA synuclein, alpha (non A4 component of amyloid precursor)
SOGA1 suppressor of glucose, autophagy associated 1
SPTB spectrin, beta, erythrocytic
STOML1 stomatin (EPB72)-like 1
TFF2 trefoil factor 2
TPM1 tropomyosin 1 (alpha)
TSPAN4 tetraspanin 4
UROD uroporphyrinogen decarboxylase
USP53 ubiquitin specific peptidase 53
WWOX WW domain containing oxidoreductase
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZBTB16 zinc finger and BTB domain containing 16
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF335 zinc finger protein 335

decreased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ACPP acid phosphatase, prostate
ADGRE3 adhesion G protein-coupled receptor E3
ALS2CL ALS2 C-terminal like
ARID5A AT rich interactive domain 5A (MRF1-like)
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BSCL2 Berardinelli-Seip congenital lipodystrophy 2 (seipin)
C2ORF27A chromosome 2 open reading frame 27A
C2ORF44 chromosome 2 open reading frame 44
CAMK4 calcium/calmodulin-dependent protein kinase IV
CD300C CD300c molecule
CEP170B centrosomal protein 170B
CES3 carboxylesterase 3
CIDEC cell death-inducing DFFA-like effector c
CLSPN claspin
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
COQ6 coenzyme Q6 monooxygenase
CORT cortistatin
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa
CRYL1 crystallin, lambda 1
DOK3 docking protein 3
EDEM2 ER degradation enhancer, mannosidase alpha-like 2
EEF1A2 eukaryotic translation elongation factor 1 alpha 2
EPHA4 EPH receptor A4
EXOC6B exocyst complex component 6B
EXOSC1 exosome component 1
FMOD fibromodulin
FSTL3 follistatin-like 3 (secreted glycoprotein)
GPR27 G protein-coupled receptor 27
GPRIN2 G protein regulated inducer of neurite outgrowth 2
HAAO 3-hydroxyanthranilate 3,4-dioxygenase
HIST1H2AI histone cluster 1, H2ai
HIST1H2BI histone cluster 1, H2bi
HIST3H2A histone cluster 3, H2a
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
IL22 interleukin 22
IQCC IQ motif containing C
IRF7 interferon regulatory factor 7
ITGB7 integrin, beta 7
KIAA1107 KIAA1107
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRT8P12 keratin 8 pseudogene 12
LAX1 lymphocyte transmembrane adaptor 1
LTC4S leukotriene C4 synthase
LY6E lymphocyte antigen 6 complex, locus E
MAGEF1 melanoma antigen family F1
MOCS3 molybdenum cofactor synthesis 3
MUC3A mucin 3A, cell surface associated
NIPAL2 NIPA-like domain containing 2
NOL10 nucleolar protein 10
NSUN3 NOP2/Sun domain family, member 3
PAQR6 progestin and adipoQ receptor family member VI
PGP phosphoglycolate phosphatase
PHC1 polyhomeotic homolog 1 (Drosophila)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific)
PLP1 proteolipid protein 1
PMFBP1 polyamine modulated factor 1 binding protein 1
PNOC prepronociceptin
POM121 POM121 transmembrane nucleoporin
PPFIA4 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
PRICKLE3 prickle homolog 3 (Drosophila)
PROCR protein C receptor, endothelial
PRR14L proline rich 14-like
PRSS12 protease, serine, 12 (neurotrypsin, motopsin)
PYHIN1 pyrin and HIN domain family, member 1
RBM42 RNA binding motif protein 42
RETN resistin
RFPL3 ret finger protein-like 3
RNF121 ring finger protein 121
RRS1 RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
SAMD9 sterile alpha motif domain containing 9
SGPP1 sphingosine-1-phosphate phosphatase 1
SLC35F6 solute carrier family 35, member F6
SNAI1 snail family zinc finger 1
SOX12 SRY (sex determining region Y)-box 12
SPATA1 spermatogenesis associated 1
SPINT1 serine peptidase inhibitor, Kunitz type 1
STX17 syntaxin 17
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TBX19 T-box 19
TESK1 testis-specific kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TMEM177 transmembrane protein 177
TMEM242 transmembrane protein 242
TPM3 tropomyosin 3
TRAF2 TNF receptor-associated factor 2
TSPAN5 tetraspanin 5
TWSG1 twisted gastrulation BMP signaling modulator 1
UCN urocortin
WASF3 WAS protein family, member 3
XAB2 XPA binding protein 2
ZBED8 zinc finger, BED-type containing 8
ZBTB22 zinc finger and BTB domain containing 22
ZDHHC14 zinc finger, DHHC-type containing 14
ZNF43 zinc finger protein 43
ZNF480 zinc finger protein 480
ZNF668 zinc finger protein 668
ZNF862 zinc finger protein 862