sulfaguanidine-4839 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the sulfaguanidine-4839 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
ADAM23 ADAM metallopeptidase domain 23
ADGRA2 adhesion G protein-coupled receptor A2
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AIF1 allograft inflammatory factor 1
ALOX12 arachidonate 12-lipoxygenase
AMPD1 adenosine monophosphate deaminase 1
ATXN2L ataxin 2-like
AVPR1B arginine vasopressin receptor 1B
B3GNT4 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
BAIAP3 BAI1-associated protein 3
BAZ2A bromodomain adjacent to zinc finger domain, 2A
BCO1 beta-carotene oxygenase 1
BIN1 bridging integrator 1
BTF3P11 basic transcription factor 3 pseudogene 11
C17ORF59 chromosome 17 open reading frame 59
C22ORF46 chromosome 22 open reading frame 46
CBX8 chromobox homolog 8
CCRL2 chemokine (C-C motif) receptor-like 2
CDK20 cyclin-dependent kinase 20
CEP250 centrosomal protein 250kDa
CHRNA2 cholinergic receptor, nicotinic, alpha 2 (neuronal)
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CLCN4 chloride channel, voltage-sensitive 4
CLGN calmegin
COL1A1 collagen, type I, alpha 1
COL5A2 collagen, type V, alpha 2
CTH cystathionine gamma-lyase
DCAF4 DDB1 and CUL4 associated factor 4
DCTN1 dynactin 1
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34
DSCR3 Down syndrome critical region 3
EXT1 exostosin glycosyltransferase 1
FAIM2 Fas apoptotic inhibitory molecule 2
FGF16 fibroblast growth factor 16
FOXN3 forkhead box N3
FST follistatin
GPR1 G protein-coupled receptor 1
HBEGF heparin-binding EGF-like growth factor
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase)
HMGN5 high mobility group nucleosome binding domain 5
HSDL2 hydroxysteroid dehydrogenase like 2
HTR6 5-hydroxytryptamine (serotonin) receptor 6, G protein-coupled
IGHA1 immunoglobulin heavy constant alpha 1
IGLJ3 immunoglobulin lambda joining 3
IL22 interleukin 22
ITGA6 integrin, alpha 6
ITM2C integral membrane protein 2C
KCNG1 potassium channel, voltage gated modifier subfamily G, member 1
KLHL22 kelch-like family member 22
LARP7 La ribonucleoprotein domain family, member 7
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LRRC1 leucine rich repeat containing 1
MAPK7 mitogen-activated protein kinase 7
MAST2 microtubule associated serine/threonine kinase 2
MST1 macrophage stimulating 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MYB v-myb avian myeloblastosis viral oncogene homolog
NCR2 natural cytotoxicity triggering receptor 2
NDOR1 NADPH dependent diflavin oxidoreductase 1
NT5M 5',3'-nucleotidase, mitochondrial
OSGIN2 oxidative stress induced growth inhibitor family member 2
OVOL1 ovo-like zinc finger 1
PATZ1 POZ (BTB) and AT hook containing zinc finger 1
PCDHGA10 protocadherin gamma subfamily A, 10
PCLO piccolo presynaptic cytomatrix protein
PLCD1 phospholipase C, delta 1
PLEKHF1 pleckstrin homology domain containing, family F (with FYVE domain) member 1
PLK4 polo-like kinase 4
POM121 POM121 transmembrane nucleoporin
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
RAD23B RAD23 homolog B (S. cerevisiae)
RCAN1 regulator of calcineurin 1
S100A8 S100 calcium binding protein A8
SALL1 spalt-like transcription factor 1
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SH3BP2 SH3-domain binding protein 2
SIRT5 sirtuin 5
SNCAIP synuclein, alpha interacting protein
SP100 SP100 nuclear antigen
SRSF7 serine/arginine-rich splicing factor 7
SSTR4 somatostatin receptor 4
STAB2 stabilin 2
SUGP1 SURP and G patch domain containing 1
SYNDIG1 synapse differentiation inducing 1
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TFPI tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
THTPA thiamine triphosphatase
TJAP1 tight junction associated protein 1 (peripheral)
TNFRSF11B tumor necrosis factor receptor superfamily, member 11b
TSNAXIP1 translin-associated factor X interacting protein 1
TTC38 tetratricopeptide repeat domain 38
UGT2B15 UDP glucuronosyltransferase 2 family, polypeptide B15
VN1R1 vomeronasal 1 receptor 1
WNT10B wingless-type MMTV integration site family, member 10B
WSB1 WD repeat and SOCS box containing 1
XRCC4 X-ray repair complementing defective repair in Chinese hamster cells 4
ZNF280A zinc finger protein 280A
ZNF442 zinc finger protein 442

decreased expression

Symbol Name
ABCC4 ATP-binding cassette, sub-family C (CFTR/MRP), member 4
ADCY6 adenylate cyclase 6
ADPRM ADP-ribose/CDP-alcohol diphosphatase, manganese-dependent
ALOX12P2 arachidonate 12-lipoxygenase pseudogene 2
ANXA2P3 annexin A2 pseudogene 3
ARRB1 arrestin, beta 1
ARRB2 arrestin, beta 2
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
C1ORF159 chromosome 1 open reading frame 159
C1QTNF9B-AS1 C1QTNF9B antisense RNA 1
C9ORF40 chromosome 9 open reading frame 40
CAMKMT calmodulin-lysine N-methyltransferase
CAMTA2 calmodulin binding transcription activator 2
CCDC186 coiled-coil domain containing 186
CDK3 cyclin-dependent kinase 3
CENPJ centromere protein J
CEP85 centrosomal protein 85kDa
CFAP44 cilia and flagella associated protein 44
CHKB choline kinase beta
CHPF chondroitin polymerizing factor
CHST10 carbohydrate sulfotransferase 10
CISH cytokine inducible SH2-containing protein
CLCN2 chloride channel, voltage-sensitive 2
CLDND1 claudin domain containing 1
CLEC16A C-type lectin domain family 16, member A
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CRYZL1 crystallin, zeta (quinone reductase)-like 1
CXADR coxsackie virus and adenovirus receptor
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DOCK1 dedicator of cytokinesis 1
DSCAM Down syndrome cell adhesion molecule
EGLN3 egl-9 family hypoxia-inducible factor 3
EXOC5 exocyst complex component 5
FADS2 fatty acid desaturase 2
FGF23 fibroblast growth factor 23
FLCN folliculin
FLJ21369 uncharacterized protein FLJ21369
FSTL3 follistatin-like 3 (secreted glycoprotein)
GEMIN8 gem (nuclear organelle) associated protein 8
GSTT1 glutathione S-transferase theta 1
HELZ helicase with zinc finger
HLA-J major histocompatibility complex, class I, J (pseudogene)
IFT140 intraflagellar transport 140
IFT81 intraflagellar transport 81
KIAA0895 KIAA0895
KREMEN2 kringle containing transmembrane protein 2
MANBA mannosidase, beta A, lysosomal
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MTCL1 microtubule crosslinking factor 1
MVD mevalonate (diphospho) decarboxylase
MXD3 MAX dimerization protein 3
NACA2 nascent polypeptide-associated complex alpha subunit 2
NDRG4 NDRG family member 4
NOD1 nucleotide-binding oligomerization domain containing 1
NPY5R neuropeptide Y receptor Y5
NR2C2 nuclear receptor subfamily 2, group C, member 2
NT5DC3 5'-nucleotidase domain containing 3
OPA3 optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OVGP1 oviductal glycoprotein 1, 120kDa
PHLPP1 PH domain and leucine rich repeat protein phosphatase 1
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLEKHA6 pleckstrin homology domain containing, family A member 6
PNPLA6 patatin-like phospholipase domain containing 6
PRICKLE3 prickle homolog 3 (Drosophila)
PRODH proline dehydrogenase (oxidase) 1
PTPRE protein tyrosine phosphatase, receptor type, E
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
ROBO3 roundabout, axon guidance receptor, homolog 3 (Drosophila)
RPL10L ribosomal protein L10-like
RUNDC3B RUN domain containing 3B
SAYSD1 SAYSVFN motif domain containing 1
SCN1B sodium channel, voltage gated, type I beta subunit
SLC20A2 solute carrier family 20 (phosphate transporter), member 2
SLC22A4 solute carrier family 22 (organic cation/zwitterion transporter), member 4
SLC37A1 solute carrier family 37 (glucose-6-phosphate transporter), member 1
SMIM14 small integral membrane protein 14
SND1-IT1 SND1 intronic transcript 1
SPAG4 sperm associated antigen 4
SREK1IP1 SREK1-interacting protein 1
STAG3L4 stromal antigen 3-like 4 (pseudogene)
STRA6 stimulated by retinoic acid 6
SUV39H1 suppressor of variegation 3-9 homolog 1 (Drosophila)
TMCO3 transmembrane and coiled-coil domains 3
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TUBA3C tubulin, alpha 3c
UBE2NL ubiquitin-conjugating enzyme E2N-like (gene/pseudogene)
UBTD1 ubiquitin domain containing 1
URM1 ubiquitin related modifier 1
VASH2 vasohibin 2
VAX2 ventral anterior homeobox 2
ZBED1 zinc finger, BED-type containing 1
ZDHHC18 zinc finger, DHHC-type containing 18
ZNF16 zinc finger protein 16
ZNF205 zinc finger protein 205
ZNF510 zinc finger protein 510