sulfafurazole-4661 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the sulfafurazole-4661 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AADAC arylacetamide deacetylase
AAGAB alpha- and gamma-adaptin binding protein
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ACOT11 acyl-CoA thioesterase 11
ACTA2 actin, alpha 2, smooth muscle, aorta
ANKRD7 ankyrin repeat domain 7
APOB apolipoprotein B
ARMC4 armadillo repeat containing 4
ARTN artemin
ASCL1 achaete-scute family bHLH transcription factor 1
ATF5 activating transcription factor 5
ATP11A ATPase, class VI, type 11A
ATXN2L ataxin 2-like
B3GAT1 beta-1,3-glucuronyltransferase 1
B9D1 B9 protein domain 1
BTF3P11 basic transcription factor 3 pseudogene 11
C22ORF24 chromosome 22 open reading frame 24
C3 complement component 3
CACNA1I calcium channel, voltage-dependent, T type, alpha 1I subunit
CACNG4 calcium channel, voltage-dependent, gamma subunit 4
CD28 CD28 molecule
CRLF2 cytokine receptor-like factor 2
CXCR4 chemokine (C-X-C motif) receptor 4
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DGKE diacylglycerol kinase, epsilon 64kDa
DICER1 dicer 1, ribonuclease type III
EGFL7 EGF-like-domain, multiple 7
EGFR epidermal growth factor receptor
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPB41L1 erythrocyte membrane protein band 4.1-like 1
EXD3 exonuclease 3'-5' domain containing 3
EXOC7 exocyst complex component 7
FAM134B family with sequence similarity 134, member B
FMOD fibromodulin
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase)
GAL galanin/GMAP prepropeptide
GREM2 gremlin 2, DAN family BMP antagonist
GSTTP1 glutathione S-transferase theta pseudogene 1
GTPBP1 GTP binding protein 1
GYG2 glycogenin 2
HIST1H2BM histone cluster 1, H2bm
HLF hepatic leukemia factor
HOMER3 homer scaffolding protein 3
HSPG2 heparan sulfate proteoglycan 2
KCNJ15 potassium channel, inwardly rectifying subfamily J, member 15
KDELR3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
KIF21B kinesin family member 21B
L3MBTL1 l(3)mbt-like 1 (Drosophila)
LAMC2 laminin, gamma 2
LGALS8 lectin, galactoside-binding, soluble, 8
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1
LY9 lymphocyte antigen 9
LYVE1 lymphatic vessel endothelial hyaluronan receptor 1
MAPK11 mitogen-activated protein kinase 11
MRC2 mannose receptor, C type 2
NCBP1 nuclear cap binding protein subunit 1, 80kDa
NCF4 neutrophil cytosolic factor 4, 40kDa
NGF nerve growth factor (beta polypeptide)
NIPAL2 NIPA-like domain containing 2
NMUR1 neuromedin U receptor 1
NRXN2 neurexin 2
NUP54 nucleoporin 54kDa
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PAX9 paired box 9
PCYT1A phosphate cytidylyltransferase 1, choline, alpha
PLXNB3 plexin B3
PPARD peroxisome proliferator-activated receptor delta
PROZ protein Z, vitamin K-dependent plasma glycoprotein
PTRF polymerase I and transcript release factor
RAB26 RAB26, member RAS oncogene family
RAD51D RAD51 paralog D
RAPGEF1 Rap guanine nucleotide exchange factor (GEF) 1
RB1 retinoblastoma 1
RBM12B RNA binding motif protein 12B
RECQL5 RecQ protein-like 5
RNF43 ring finger protein 43
RPL23AP32 ribosomal protein L23a pseudogene 32
RSU1 Ras suppressor protein 1
RUNX1 runt-related transcription factor 1
SBNO1 strawberry notch homolog 1 (Drosophila)
SLC35F5 solute carrier family 35, member F5
SMG6 SMG6 nonsense mediated mRNA decay factor
SPRED2 sprouty-related, EVH1 domain containing 2
SRC SRC proto-oncogene, non-receptor tyrosine kinase
STOML1 stomatin (EPB72)-like 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TBL2 transducin (beta)-like 2
TLN2 talin 2
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TPP1 tripeptidyl peptidase I
TSHZ2 teashirt zinc finger homeobox 2
TTC12 tetratricopeptide repeat domain 12
WSB1 WD repeat and SOCS box containing 1
XDH xanthine dehydrogenase
ZBTB7B zinc finger and BTB domain containing 7B
ZMIZ2 zinc finger, MIZ-type containing 2
ZNF343 zinc finger protein 343
ZNF749 zinc finger protein 749

decreased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AFF4 AF4/FMR2 family, member 4
AGO4 argonaute RISC catalytic component 4
AGT angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
ANKRD40 ankyrin repeat domain 40
ANP32A-IT1 ANP32A intronic transcript 1
APOLD1 apolipoprotein L domain containing 1
ATAD5 ATPase family, AAA domain containing 5
AURKC aurora kinase C
BET1L Bet1 golgi vesicular membrane trafficking protein-like
C11ORF63 chromosome 11 open reading frame 63
C11ORF80 chromosome 11 open reading frame 80
C1R complement component 1, r subcomponent
CASP5 caspase 5, apoptosis-related cysteine peptidase
CCDC85C coiled-coil domain containing 85C
CD101 CD101 molecule
CDHR2 cadherin-related family member 2
CLCN5 chloride channel, voltage-sensitive 5
CLCN6 chloride channel, voltage-sensitive 6
CNN1 calponin 1, basic, smooth muscle
CNR2 cannabinoid receptor 2 (macrophage)
CPA4 carboxypeptidase A4
CPPED1 calcineurin-like phosphoesterase domain containing 1
DDX54 DEAD (Asp-Glu-Ala-Asp) box polypeptide 54
DNAJC28 DnaJ (Hsp40) homolog, subfamily C, member 28
DTX2 deltex 2, E3 ubiquitin ligase
EDN1 endothelin 1
EFCAB2 EF-hand calcium binding domain 2
ELSPBP1 epididymal sperm binding protein 1
FAM186A family with sequence similarity 186, member A
FAM188A family with sequence similarity 188, member A
FANCC Fanconi anemia, complementation group C
FBXL7 F-box and leucine-rich repeat protein 7
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
FLJ21369 uncharacterized protein FLJ21369
FMO4 flavin containing monooxygenase 4
FRMPD1 FERM and PDZ domain containing 1
GAB2 GRB2-associated binding protein 2
GPR27 G protein-coupled receptor 27
HIST1H3I histone cluster 1, H3i
HOXA7 homeobox A7
HOXC8 homeobox C8
IFT140 intraflagellar transport 140
IL32 interleukin 32
IPO8 importin 8
KCNA5 potassium channel, voltage gated shaker related subfamily A, member 5
KCNS3 potassium voltage-gated channel, modifier subfamily S, member 3
KIAA0513 KIAA0513
KIAA0753 KIAA0753
KIAA1462 KIAA1462
KRT20 keratin 20, type I
LIN7B lin-7 homolog B (C. elegans)
LINC00472 long intergenic non-protein coding RNA 472
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LY96 lymphocyte antigen 96
MCMBP minichromosome maintenance complex binding protein
METTL16 methyltransferase like 16
MYOZ1 myozenin 1
NAG18 NAG18 mRNA
NBEAL2 neurobeachin-like 2
NDE1 nudE neurodevelopment protein 1
NID2 nidogen 2 (osteonidogen)
NME5 NME/NM23 family member 5
PARM1 prostate androgen-regulated mucin-like protein 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLEKHB1 pleckstrin homology domain containing, family B (evectins) member 1
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PPT2 palmitoyl-protein thioesterase 2
PRR14L proline rich 14-like
RAB17 RAB17, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAPGEFL1 Rap guanine nucleotide exchange factor (GEF)-like 1
RNF126P1 ring finger protein 126 pseudogene 1
ROM1 retinal outer segment membrane protein 1
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
SH2D2A SH2 domain containing 2A
SKIL SKI-like proto-oncogene
SLC14A1 solute carrier family 14 (urea transporter), member 1 (Kidd blood group)
SLC22A1 solute carrier family 22 (organic cation transporter), member 1
SMAD7 SMAD family member 7
SPATA2L spermatogenesis associated 2-like
SPINK1 serine peptidase inhibitor, Kazal type 1
SYNGR3 synaptogyrin 3
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN2 tectonic family member 2
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRMT2A tRNA methyltransferase 2 homolog A (S. cerevisiae)
TSNAXIP1 translin-associated factor X interacting protein 1
TTLL1 tubulin tyrosine ligase-like family member 1
TTLL7 tubulin tyrosine ligase-like family member 7
TUBA3D tubulin, alpha 3d
TUBA4B tubulin, alpha 4b
TWISTNB TWIST neighbor
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
WNT7A wingless-type MMTV integration site family, member 7A
ZNF778 zinc finger protein 778