sulfadoxine-7205 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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199 genes differentially expressed following the sulfadoxine-7205 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ACTN1 actinin, alpha 1
AK2 adenylate kinase 2
AKAP7 A kinase (PRKA) anchor protein 7
ALDH6A1 aldehyde dehydrogenase 6 family, member A1
APBA2 amyloid beta (A4) precursor protein-binding, family A, member 2
ATM ATM serine/threonine kinase
BAZ1B bromodomain adjacent to zinc finger domain, 1B
BBS9 Bardet-Biedl syndrome 9
BMP6 bone morphogenetic protein 6
C14ORF79 chromosome 14 open reading frame 79
C8ORF60 chromosome 8 open reading frame 60
CA1 carbonic anhydrase I
CACNB4 calcium channel, voltage-dependent, beta 4 subunit
CCRL2 chemokine (C-C motif) receptor-like 2
CELSR1 cadherin, EGF LAG seven-pass G-type receptor 1
CLGN calmegin
CR1 complement component (3b/4b) receptor 1 (Knops blood group)
CRYBB2P1 crystallin, beta B2 pseudogene 1
CSTA cystatin A (stefin A)
CXCR4 chemokine (C-X-C motif) receptor 4
DDIT3 DNA-damage-inducible transcript 3
DENND1C DENN/MADD domain containing 1C
DHODH dihydroorotate dehydrogenase (quinone)
DNAL4 dynein, axonemal, light chain 4
ELL elongation factor RNA polymerase II
ERCC6 excision repair cross-complementation group 6
EXO5 exonuclease 5
EXT1 exostosin glycosyltransferase 1
GRM8 glutamate receptor, metabotropic 8
GRPR gastrin-releasing peptide receptor
GSTCD glutathione S-transferase, C-terminal domain containing
HFE hemochromatosis
HOXC8 homeobox C8
IGHA1 immunoglobulin heavy constant alpha 1
IL2RB interleukin 2 receptor, beta
INS insulin
ITPKB inositol-trisphosphate 3-kinase B
KDM6A lysine (K)-specific demethylase 6A
KIAA0087 KIAA0087
KIAA0319L KIAA0319-like
KLHL22 kelch-like family member 22
KMT2A lysine (K)-specific methyltransferase 2A
LAPTM5 lysosomal protein transmembrane 5
LIG4 ligase IV, DNA, ATP-dependent
LIMK1 LIM domain kinase 1
LRRC6 leucine rich repeat containing 6
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LTBP2 latent transforming growth factor beta binding protein 2
MNDA myeloid cell nuclear differentiation antigen
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
NCOA2 nuclear receptor coactivator 2
NCOR2 nuclear receptor corepressor 2
NCR2 natural cytotoxicity triggering receptor 2
NDRG2 NDRG family member 2
NIPAL2 NIPA-like domain containing 2
NME5 NME/NM23 family member 5
NUP88 nucleoporin 88kDa
ORAI2 ORAI calcium release-activated calcium modulator 2
OVOL1 ovo-like zinc finger 1
PAX2 paired box 2
PDGFB platelet-derived growth factor beta polypeptide
PEX26 peroxisomal biogenesis factor 26
PHLDB1 pleckstrin homology-like domain, family B, member 1
PLEKHM1 pleckstrin homology domain containing, family M (with RUN domain) member 1
POU5F1B POU class 5 homeobox 1B
PRF1 perforin 1 (pore forming protein)
PRPH peripherin
PXDC1 PX domain containing 1
RALGPS2 Ral GEF with PH domain and SH3 binding motif 2
RARB retinoic acid receptor, beta
RCHY1 ring finger and CHY zinc finger domain containing 1, E3 ubiquitin protein ligase
RECQL5 RecQ protein-like 5
RGS12 regulator of G-protein signaling 12
RGS6 regulator of G-protein signaling 6
RPS4Y1 ribosomal protein S4, Y-linked 1
SCN4A sodium channel, voltage gated, type IV alpha subunit
SDHB succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
SEMA4A sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
SH3BP2 SH3-domain binding protein 2
SIRT3 sirtuin 3
SLC1A7 solute carrier family 1 (glutamate transporter), member 7
SOX9 SRY (sex determining region Y)-box 9
SYNGR1 synaptogyrin 1
TAF1C TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa
TAF4B TAF4b RNA polymerase II, TATA box binding protein (TBP)-associated factor, 105kDa
TAT tyrosine aminotransferase
TBC1D17 TBC1 domain family, member 17
THBD thrombomodulin
THOC5 THO complex 5
TLE4 transducin-like enhancer of split 4
TOP3A topoisomerase (DNA) III alpha
UBXN1 UBX domain protein 1
UTP18 UTP18 small subunit (SSU) processome component homolog (yeast)
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2)
VPS9D1 VPS9 domain containing 1
WIZ widely interspaced zinc finger motifs
ZNF136 zinc finger protein 136
ZNF222 zinc finger protein 222
ZNF324 zinc finger protein 324
ZNF350 zinc finger protein 350

decreased expression

Symbol Name
ADRA2C adrenoceptor alpha 2C
ARID3A AT rich interactive domain 3A (BRIGHT-like)
ASB7 ankyrin repeat and SOCS box containing 7
ATG9A autophagy related 9A
BAHD1 bromo adjacent homology domain containing 1
C1ORF159 chromosome 1 open reading frame 159
C22ORF29 chromosome 22 open reading frame 29
C7ORF43 chromosome 7 open reading frame 43
CAPG capping protein (actin filament), gelsolin-like
CCZ1B CCZ1 vacuolar protein trafficking and biogenesis associated homolog B (S. cerevisiae)
CDK20 cyclin-dependent kinase 20
CDK3 cyclin-dependent kinase 3
CDR2L cerebellar degeneration-related protein 2-like
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CFD complement factor D (adipsin)
CHKB choline kinase beta
CHMP6 charged multivesicular body protein 6
CNGB3 cyclic nucleotide gated channel beta 3
CNNM4 cyclin and CBS domain divalent metal cation transport mediator 4
COCH cochlin
CTAGE9 CTAGE family, member 9
DENND4A DENN/MADD domain containing 4A
EEA1 early endosome antigen 1
EGLN3 egl-9 family hypoxia-inducible factor 3
EHHADH enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase
ELOVL4 ELOVL fatty acid elongase 4
ENO2 enolase 2 (gamma, neuronal)
EOGT EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
FAAH fatty acid amide hydrolase
FAM131A family with sequence similarity 131, member A
FAM160B2 family with sequence similarity 160, member B2
FBRS fibrosin
GLS2 glutaminase 2 (liver, mitochondrial)
GMEB1 glucocorticoid modulatory element binding protein 1
HIST1H2BC histone cluster 1, H2bc
HIST1H2BO histone cluster 1, H2bo
HLA-DRB1 major histocompatibility complex, class II, DR beta 1
IL17RA interleukin 17 receptor A
IREB2 iron-responsive element binding protein 2
IRF6 interferon regulatory factor 6
KCNMB4 potassium channel subfamily M regulatory beta subunit 4
KLHL21 kelch-like family member 21
KLHL26 kelch-like family member 26
LAMA3 laminin, alpha 3
LHX1 LIM homeobox 1
LRRC20 leucine rich repeat containing 20
MAST3 microtubule associated serine/threonine kinase 3
MBIP MAP3K12 binding inhibitory protein 1
MCOLN3 mucolipin 3
MICAL3 microtubule associated monooxygenase, calponin and LIM domain containing 3
MKS1 Meckel syndrome, type 1
MOSPD3 motile sperm domain containing 3
MYH9 myosin, heavy chain 9, non-muscle
NACA2 nascent polypeptide-associated complex alpha subunit 2
NBEAL2 neurobeachin-like 2
NDRG1 N-myc downstream regulated 1
NRSN2 neurensin 2
PACS1 phosphofurin acidic cluster sorting protein 1
PARD6A par-6 family cell polarity regulator alpha
PCDHB3 protocadherin beta 3
PCDHGB5 protocadherin gamma subfamily B, 5
PDPR pyruvate dehydrogenase phosphatase regulatory subunit
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PSTPIP2 proline-serine-threonine phosphatase interacting protein 2
PTK6 protein tyrosine kinase 6
RAB8B RAB8B, member RAS oncogene family
REEP4 receptor accessory protein 4
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
S100A4 S100 calcium binding protein A4
SEC22A SEC22 vesicle trafficking protein homolog A (S. cerevisiae)
SEC61A2 Sec61 alpha 2 subunit (S. cerevisiae)
SERPINA3 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter)
SLC25A10 solute carrier family 25 (mitochondrial carrier; dicarboxylate transporter), member 10
SLC41A3 solute carrier family 41, member 3
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SPRYD7 SPRY domain containing 7
SPSB1 splA/ryanodine receptor domain and SOCS box containing 1
STBD1 starch binding domain 1
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
TBX19 T-box 19
TESK1 testis-specific kinase 1
TICAM1 toll-like receptor adaptor molecule 1
TLN1 talin 1
TM7SF3 transmembrane 7 superfamily member 3
TMEM180 transmembrane protein 180
TMEM2 transmembrane protein 2
TTC23 tetratricopeptide repeat domain 23
TUBG2 tubulin, gamma 2
USB1 U6 snRNA biogenesis 1
WDR4 WD repeat domain 4
ZBTB48 zinc finger and BTB domain containing 48
ZC3H12A zinc finger CCCH-type containing 12A
ZNF205 zinc finger protein 205
ZNF211 zinc finger protein 211
ZNF268 zinc finger protein 268
ZNF492 zinc finger protein 492
ZNF668 zinc finger protein 668
ZNF672 zinc finger protein 672