sulfadimidine-4322 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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198 genes differentially expressed following the sulfadimidine-4322 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADAM28 ADAM metallopeptidase domain 28
AGPAT2 1-acylglycerol-3-phosphate O-acyltransferase 2
AKR1C2 aldo-keto reductase family 1, member C2
ALDH3B1 aldehyde dehydrogenase 3 family, member B1
ANKRD6 ankyrin repeat domain 6
APOM apolipoprotein M
ARNT aryl hydrocarbon receptor nuclear translocator
BTBD18 BTB (POZ) domain containing 18
C1ORF68 chromosome 1 open reading frame 68
C3 complement component 3
CBS cystathionine-beta-synthase
CDK18 cyclin-dependent kinase 18
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CHRNB1 cholinergic receptor, nicotinic, beta 1 (muscle)
CLTB clathrin, light chain B
COL7A1 collagen, type VII, alpha 1
COMT catechol-O-methyltransferase
CTIF CBP80/20-dependent translation initiation factor
CUL7 cullin 7
DDX51 DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
DGCR8 DGCR8 microprocessor complex subunit
DKFZP434C153 DKFZP434C153 protein
DNAJB12 DnaJ (Hsp40) homolog, subfamily B, member 12
DPF1 D4, zinc and double PHD fingers family 1
DTNA dystrobrevin, alpha
EML3 echinoderm microtubule associated protein like 3
ERN2 endoplasmic reticulum to nucleus signaling 2
ESR1 estrogen receptor 1
ETS1 v-ets avian erythroblastosis virus E26 oncogene homolog 1
FAM89B family with sequence similarity 89, member B
FCMR Fc fragment of IgM receptor
FHL3 four and a half LIM domains 3
FKBP10 FK506 binding protein 10, 65 kDa
FRMD1 FERM domain containing 1
FSCN3 fascin actin-bundling protein 3, testicular
FUBP1 far upstream element (FUSE) binding protein 1
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GPR161 G protein-coupled receptor 161
GPR182 G protein-coupled receptor 182
GRIK5 glutamate receptor, ionotropic, kainate 5
GSK3A glycogen synthase kinase 3 alpha
HIST1H2AL histone cluster 1, H2al
HUWE1 HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase
IL11 interleukin 11
IL2RB interleukin 2 receptor, beta
INPP5J inositol polyphosphate-5-phosphatase J
INTS1 integrator complex subunit 1
IQSEC2 IQ motif and Sec7 domain 2
JUND jun D proto-oncogene
KCNMB1 potassium channel subfamily M regulatory beta subunit 1
KIAA0754 KIAA0754
KLHL25 kelch-like family member 25
LGALS8 lectin, galactoside-binding, soluble, 8
LIME1 Lck interacting transmembrane adaptor 1
LOC100294391 uncharacterized LOC100294391
LOC157562 uncharacterized LOC157562
LRCH4 leucine-rich repeats and calponin homology (CH) domain containing 4
LTB4R leukotriene B4 receptor
MMP14 matrix metallopeptidase 14 (membrane-inserted)
NPAS2 neuronal PAS domain protein 2
NPRL2 nitrogen permease regulator-like 2 (S. cerevisiae)
NPRL3 nitrogen permease regulator-like 3 (S. cerevisiae)
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
P2RY4 pyrimidinergic receptor P2Y, G-protein coupled, 4
PAOX polyamine oxidase (exo-N4-amino)
PASK PAS domain containing serine/threonine kinase
PBX1 pre-B-cell leukemia homeobox 1
PCNXL2 pecanex-like 2 (Drosophila)
PER1 period circadian clock 1
PFKFB4 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
PHLDB1 pleckstrin homology-like domain, family B, member 1
POLM polymerase (DNA directed), mu
PPIL2 peptidylprolyl isomerase (cyclophilin)-like 2
PQLC3 PQ loop repeat containing 3
RARA retinoic acid receptor, alpha
RGS4 regulator of G-protein signaling 4
SEC14L4 SEC14-like 4 (S. cerevisiae)
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
SERPINA1 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SH3D21 SH3 domain containing 21
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMYD2 SET and MYND domain containing 2
SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)
TLN2 talin 2
TLR1 toll-like receptor 1
TMBIM1 transmembrane BAX inhibitor motif containing 1
TNFRSF25 tumor necrosis factor receptor superfamily, member 25
TNPO2 transportin 2
TREX1 three prime repair exonuclease 1
TRIM3 tripartite motif containing 3
TUBA3C tubulin, alpha 3c
USB1 U6 snRNA biogenesis 1
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae)
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZFP64 ZFP64 zinc finger protein
ZNF639 zinc finger protein 639
ZNF75D zinc finger protein 75D

decreased expression

Symbol Name
ACSL5 acyl-CoA synthetase long-chain family member 5
ACTC1 actin, alpha, cardiac muscle 1
ALG12 ALG12, alpha-1,6-mannosyltransferase
ANKRD1 ankyrin repeat domain 1 (cardiac muscle)
ARHGEF38 Rho guanine nucleotide exchange factor (GEF) 38
ATAT1 alpha tubulin acetyltransferase 1
BTF3P12 basic transcription factor 3 pseudogene 12
C17ORF53 chromosome 17 open reading frame 53
C1ORF54 chromosome 1 open reading frame 54
C9ORF9 chromosome 9 open reading frame 9
CACNA2D1 calcium channel, voltage-dependent, alpha 2/delta subunit 1
CCDC177 coiled-coil domain containing 177
CD53 CD53 molecule
CDK6 cyclin-dependent kinase 6
CHRDL1 chordin-like 1
CLCN5 chloride channel, voltage-sensitive 5
CNGB3 cyclic nucleotide gated channel beta 3
CRISPLD2 cysteine-rich secretory protein LCCL domain containing 2
CRMP1 collapsin response mediator protein 1
CSF1R colony stimulating factor 1 receptor
CXCL3 chemokine (C-X-C motif) ligand 3
DBF4B DBF4 zinc finger B
DDX6 DEAD (Asp-Glu-Ala-Asp) box helicase 6
EDIL3 EGF-like repeats and discoidin I-like domains 3
EGF epidermal growth factor
EIF2S3 eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
ENTPD7 ectonucleoside triphosphate diphosphohydrolase 7
EPHA7 EPH receptor A7
EXOC6B exocyst complex component 6B
FKBP5 FK506 binding protein 5
GATC glutamyl-tRNA(Gln) amidotransferase, subunit C
GID4 GID complex subunit 4
GNG3 guanine nucleotide binding protein (G protein), gamma 3
GSTCD glutathione S-transferase, C-terminal domain containing
GTF2A1 general transcription factor IIA, 1, 19/37kDa
HERC3 HECT and RLD domain containing E3 ubiquitin protein ligase 3
HIST1H1D histone cluster 1, H1d
HIST1H1E histone cluster 1, H1e
HIST1H2AJ histone cluster 1, H2aj
HIST1H2BM histone cluster 1, H2bm
HIST1H4C histone cluster 1, H4c
HIST1H4D histone cluster 1, H4d
HOXC10 homeobox C10
HOXC11 homeobox C11
IFI6 interferon, alpha-inducible protein 6
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IL24 interleukin 24
KIRREL kin of IRRE like (Drosophila)
LINC00341 long intergenic non-protein coding RNA 341
LOC100286895 cell division cycle 27 homolog pseudogene
LOC202181 SUMO-interacting motifs containing 1 pseudogene
LPPR1 lipid phosphate phosphatase-related protein type 1
LRP2 low density lipoprotein receptor-related protein 2
MAGEH1 melanoma antigen family H1
MAL mal, T-cell differentiation protein
MIS18BP1 MIS18 binding protein 1
MTA2 metastasis associated 1 family, member 2
NCS1 neuronal calcium sensor 1
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NPFFR1 neuropeptide FF receptor 1
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSBP2 oxysterol binding protein 2
OSGIN1 oxidative stress induced growth inhibitor 1
P2RY6 pyrimidinergic receptor P2Y, G-protein coupled, 6
PDE8B phosphodiesterase 8B
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PIK3R2 phosphoinositide-3-kinase, regulatory subunit 2 (beta)
PLA2G1B phospholipase A2, group IB (pancreas)
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit
PRR14L proline rich 14-like
PTPRS protein tyrosine phosphatase, receptor type, S
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RCAN3 RCAN family member 3
RFX7 regulatory factor X, 7
S1PR1 sphingosine-1-phosphate receptor 1
SLC5A2 solute carrier family 5 (sodium/glucose cotransporter), member 2
SLC6A20 solute carrier family 6 (proline IMINO transporter), member 20
SLC9A7 solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
SLN sarcolipin
SMAD5 SMAD family member 5
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SSBP3 single stranded DNA binding protein 3
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
SUV39H2 suppressor of variegation 3-9 homolog 2 (Drosophila)
TANC2 tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2
TAOK1 TAO kinase 1
TBXAS1 thromboxane A synthase 1 (platelet)
TEAD1 TEA domain family member 1 (SV40 transcriptional enhancer factor)
TMEM159 transmembrane protein 159
TMEM209 transmembrane protein 209
TUBB2B tubulin, beta 2B class IIb
USP36 ubiquitin specific peptidase 36
VASH1 vasohibin 1
XYLT2 xylosyltransferase II
ZBTB38 zinc finger and BTB domain containing 38
ZNF124 zinc finger protein 124
ZNF669 zinc finger protein 669
ZNF749 zinc finger protein 749