sulfadimethoxine-3702 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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193 genes differentially expressed following the sulfadimethoxine-3702 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
AATK apoptosis-associated tyrosine kinase
ADAM3A ADAM metallopeptidase domain 3A (pseudogene)
ADRBK1 adrenergic, beta, receptor kinase 1
AGAP2 ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
AGRN agrin
AIM2 absent in melanoma 2
ALDH1B1 aldehyde dehydrogenase 1 family, member B1
ASMT acetylserotonin O-methyltransferase
ATP6V0A4 ATPase, H+ transporting, lysosomal V0 subunit a4
BTF3P11 basic transcription factor 3 pseudogene 11
CACNB1 calcium channel, voltage-dependent, beta 1 subunit
CADM3 cell adhesion molecule 3
CALML3 calmodulin-like 3
CCDC64 coiled-coil domain containing 64
CD58 CD58 molecule
CHN2 chimerin 2
CHRNB2 cholinergic receptor, nicotinic, beta 2 (neuronal)
CLEC3B C-type lectin domain family 3, member B
CLTA clathrin, light chain A
COL1A1 collagen, type I, alpha 1
CPNE7 copine VII
CREBZF CREB/ATF bZIP transcription factor
CSF1R colony stimulating factor 1 receptor
DEFA4 defensin, alpha 4, corticostatin
DHRS12 dehydrogenase/reductase (SDR family) member 12
DOPEY2 dopey family member 2
ECE1 endothelin converting enzyme 1
ERG v-ets avian erythroblastosis virus E26 oncogene homolog
ESR1 estrogen receptor 1
ETV2 ets variant 2
FBXO4 F-box protein 4
FGFR1 fibroblast growth factor receptor 1
GPR182 G protein-coupled receptor 182
GRIN1 glutamate receptor, ionotropic, N-methyl D-aspartate 1
HAPLN1 hyaluronan and proteoglycan link protein 1
HIST1H2BM histone cluster 1, H2bm
HLA-DOB major histocompatibility complex, class II, DO beta
HN1L hematological and neurological expressed 1-like
HP haptoglobin
IGLL1 immunoglobulin lambda-like polypeptide 1
INADL InaD-like (Drosophila)
IRF4 interferon regulatory factor 4
ITGA7 integrin, alpha 7
LDHC lactate dehydrogenase C
LIPE lipase, hormone-sensitive
LYRM9 LYR motif containing 9
MAST2 microtubule associated serine/threonine kinase 2
MCF2L MCF.2 cell line derived transforming sequence-like
MDFI MyoD family inhibitor
MEPE matrix extracellular phosphoglycoprotein
MGAM maltase-glucoamylase
MON2 MON2 homolog (S. cerevisiae)
MRC2 mannose receptor, C type 2
MTCP1 mature T-cell proliferation 1
MTSS1L metastasis suppressor 1-like
MUC5AC mucin 5AC, oligomeric mucus/gel-forming
NDST1 N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
NEUROD6 neuronal differentiation 6
NFKBIB nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, beta
NRL neural retina leucine zipper
NXPH3 neurexophilin 3
OGFR opioid growth factor receptor
OR52A1 olfactory receptor, family 52, subfamily A, member 1
PDE11A phosphodiesterase 11A
PDE4DIP phosphodiesterase 4D interacting protein
PML promyelocytic leukemia
PRKCE protein kinase C, epsilon
PRLH prolactin releasing hormone
PSTPIP1 proline-serine-threonine phosphatase interacting protein 1
PTGDS prostaglandin D2 synthase 21kDa (brain)
ROBO4 roundabout, axon guidance receptor, homolog 4 (Drosophila)
SCD stearoyl-CoA desaturase (delta-9-desaturase)
SFRP5 secreted frizzled-related protein 5
SFTPB surfactant protein B
SIX3 SIX homeobox 3
SLAMF7 SLAM family member 7
SLC24A1 solute carrier family 24 (sodium/potassium/calcium exchanger), member 1
SLC35F5 solute carrier family 35, member F5
SLC45A2 solute carrier family 45, member 2
SLC4A5 solute carrier family 4 (sodium bicarbonate cotransporter), member 5
SOX21 SRY (sex determining region Y)-box 21
SPRED2 sprouty-related, EVH1 domain containing 2
SRSF7 serine/arginine-rich splicing factor 7
ST7L suppression of tumorigenicity 7 like
TBC1D30 TBC1 domain family, member 30
TLDC1 TBC/LysM-associated domain containing 1
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TNS1 tensin 1
TPM1 tropomyosin 1 (alpha)
TRIL TLR4 interactor with leucine-rich repeats
TRIM3 tripartite motif containing 3
TSPAN32 tetraspanin 32
XIST X inactive specific transcript (non-protein coding)
XPNPEP1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
ZFP64 ZFP64 zinc finger protein
ZNF3 zinc finger protein 3
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ACTR8 ARP8 actin-related protein 8 homolog (yeast)
ADTRP androgen-dependent TFPI-regulating protein
AFF4 AF4/FMR2 family, member 4
AIM1L absent in melanoma 1-like
ALPP alkaline phosphatase, placental
ATAD5 ATPase family, AAA domain containing 5
BAG4 BCL2-associated athanogene 4
BAHCC1 BAH domain and coiled-coil containing 1
BCL11B B-cell CLL/lymphoma 11B (zinc finger protein)
BDKRB1 bradykinin receptor B1
BTBD18 BTB (POZ) domain containing 18
BTC betacellulin
C1QTNF3 C1q and tumor necrosis factor related protein 3
C9ORF40 chromosome 9 open reading frame 40
CA9 carbonic anhydrase IX
CAMKMT calmodulin-lysine N-methyltransferase
CAPN5 calpain 5
CD101 CD101 molecule
CD3D CD3d molecule, delta (CD3-TCR complex)
CDH7 cadherin 7, type 2
CDHR2 cadherin-related family member 2
CDK20 cyclin-dependent kinase 20
CDKL3 cyclin-dependent kinase-like 3
CDON cell adhesion associated, oncogene regulated
CNTFR ciliary neurotrophic factor receptor
CNTLN centlein, centrosomal protein
CRY2 cryptochrome circadian clock 2
DLK2 delta-like 2 homolog (Drosophila)
DNAH7 dynein, axonemal, heavy chain 7
ERO1LB ERO1-like beta (S. cerevisiae)
FAM189A2 family with sequence similarity 189, member A2
GEMIN8 gem (nuclear organelle) associated protein 8
GIT1 G protein-coupled receptor kinase interacting ArfGAP 1
GLS2 glutaminase 2 (liver, mitochondrial)
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
GNG7 guanine nucleotide binding protein (G protein), gamma 7
GNL3LP1 guanine nucleotide binding protein-like 3 (nucleolar)-like pseudogene 1
GPR39 G protein-coupled receptor 39
HIST1H2AI histone cluster 1, H2ai
HIST1H3I histone cluster 1, H3i
HIST2H2AA3 histone cluster 2, H2aa3
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3
HOXA1 homeobox A1
HOXC11 homeobox C11
HSD17B1 hydroxysteroid (17-beta) dehydrogenase 1
KIFC3 kinesin family member C3
KLC2 kinesin light chain 2
KLHL25 kelch-like family member 25
LOC100286895 cell division cycle 27 homolog pseudogene
LRRC61 leucine rich repeat containing 61
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP3K7CL MAP3K7 C-terminal like
MEFV Mediterranean fever
MINOS1P1 mitochondrial inner membrane organizing system 1 pseudogene 1
MRM1 mitochondrial rRNA methyltransferase 1 homolog (S. cerevisiae)
MRPL44 mitochondrial ribosomal protein L44
NARFL nuclear prelamin A recognition factor-like
NCALD neurocalcin delta
NPY1R neuropeptide Y receptor Y1
OR1D2 olfactory receptor, family 1, subfamily D, member 2
PACS1 phosphofurin acidic cluster sorting protein 1
PADI1 peptidyl arginine deiminase, type I
PAIP2B poly(A) binding protein interacting protein 2B
PARP3 poly (ADP-ribose) polymerase family, member 3
PARPBP PARP1 binding protein
PIGZ phosphatidylinositol glycan anchor biosynthesis, class Z
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PMCHL1 pro-melanin-concentrating hormone-like 1, pseudogene
PODNL1 podocan-like 1
PRR15L proline rich 15-like
PTPRH protein tyrosine phosphatase, receptor type, H
PWAR5 Prader Willi/Angelman region RNA 5
RAB4B RAB4B, member RAS oncogene family
RABL6 RAB, member RAS oncogene family-like 6
RFPL3 ret finger protein-like 3
RGCC regulator of cell cycle
RPGR retinitis pigmentosa GTPase regulator
SAYSD1 SAYSVFN motif domain containing 1
SCAMP5 secretory carrier membrane protein 5
SCML2 sex comb on midleg-like 2 (Drosophila)
SETD8 SET domain containing (lysine methyltransferase) 8
SGK2 serum/glucocorticoid regulated kinase 2
SH3TC1 SH3 domain and tetratricopeptide repeats 1
SLC16A10 solute carrier family 16 (aromatic amino acid transporter), member 10
SMA4 glucuronidase, beta pseudogene
SP4 Sp4 transcription factor
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1
SYCE1L synaptonemal complex central element protein 1-like
TAB1 TGF-beta activated kinase 1/MAP3K7 binding protein 1
VGF VGF nerve growth factor inducible
WFDC2 WAP four-disulfide core domain 2
ZNF37BP zinc finger protein 37B, pseudogene
ZNF574 zinc finger protein 574
ZNF639 zinc finger protein 639
ZNF76 zinc finger protein 76