sulfadimethoxine-3441 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

195 genes differentially expressed following the sulfadimethoxine-3441 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
APPBP2 amyloid beta precursor protein (cytoplasmic tail) binding protein 2
ARHGAP1 Rho GTPase activating protein 1
ARHGAP35 Rho GTPase activating protein 35
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARL3 ADP-ribosylation factor-like 3
ATM ATM serine/threonine kinase
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
BRE brain and reproductive organ-expressed (TNFRSF1A modulator)
C10ORF95 chromosome 10 open reading frame 95
CACNB2 calcium channel, voltage-dependent, beta 2 subunit
CALR calreticulin
CAPN9 calpain 9
CASP1 caspase 1, apoptosis-related cysteine peptidase
CASP2 caspase 2, apoptosis-related cysteine peptidase
CCDC69 coiled-coil domain containing 69
CDC14A cell division cycle 14A
CDKAL1 CDK5 regulatory subunit associated protein 1-like 1
CES2 carboxylesterase 2
CFLAR CASP8 and FADD-like apoptosis regulator
CLGN calmegin
CROCC ciliary rootlet coiled-coil, rootletin
CTAGE5 CTAGE family, member 5
DDIT3 DNA-damage-inducible transcript 3
DDR1-AS1 DDR1 antisense RNA 1 (head to head)
DIEXF digestive organ expansion factor homolog (zebrafish)
DOC2A double C2-like domains, alpha
DOCK5 dedicator of cytokinesis 5
EML2 echinoderm microtubule associated protein like 2
FBXO9 F-box protein 9
FKBP8 FK506 binding protein 8, 38kDa
FLJ11710 uncharacterized protein FLJ11710
FMOD fibromodulin
GINS4 GINS complex subunit 4 (Sld5 homolog)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPR153 G protein-coupled receptor 153
GREB1 growth regulation by estrogen in breast cancer 1
H2AFX H2A histone family, member X
HIPK3 homeodomain interacting protein kinase 3
HIST1H4F histone cluster 1, H4f
HLA-E major histocompatibility complex, class I, E
IDI2-AS1 IDI2 antisense RNA 1
ISG20 interferon stimulated exonuclease gene 20kDa
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIF13A kinesin family member 13A
KLHL22 kelch-like family member 22
LOC399491
LPPR1 lipid phosphate phosphatase-related protein type 1
LUZP1 leucine zipper protein 1
LZTS3 leucine zipper, putative tumor suppressor family member 3
MED18 mediator complex subunit 18
MVK mevalonate kinase
MYO1E myosin IE
NAB2 NGFI-A binding protein 2 (EGR1 binding protein 2)
NEIL1 nei endonuclease VIII-like 1 (E. coli)
NME5 NME/NM23 family member 5
NRGN neurogranin (protein kinase C substrate, RC3)
NUP98 nucleoporin 98kDa
NXPH4 neurexophilin 4
PACS1 phosphofurin acidic cluster sorting protein 1
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa)
PCYT2 phosphate cytidylyltransferase 2, ethanolamine
PLEC plectin
PLXNA3 plexin A3
PPAP2B phosphatidic acid phosphatase type 2B
PPP1R9A protein phosphatase 1, regulatory subunit 9A
PRKCA protein kinase C, alpha
PTPRA protein tyrosine phosphatase, receptor type, A
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RABGAP1 RAB GTPase activating protein 1
RBM5 RNA binding motif protein 5
RCAN1 regulator of calcineurin 1
RECQL5 RecQ protein-like 5
RGS3 regulator of G-protein signaling 3
RPAIN RPA interacting protein
RPS28 ribosomal protein S28
RSPH14 radial spoke head 14 homolog (Chlamydomonas)
RTEL1 regulator of telomere elongation helicase 1
S100A13 S100 calcium binding protein A13
SEC24D SEC24 family member D
SFI1 Sfi1 homolog, spindle assembly associated (yeast)
SLC22A14 solute carrier family 22, member 14
SLC35D1 solute carrier family 35 (UDP-GlcA/UDP-GalNAc transporter), member D1
SLC9A8 solute carrier family 9, subfamily A (NHE8, cation proton antiporter 8), member 8
SREK1IP1 SREK1-interacting protein 1
STS steroid sulfatase (microsomal), isozyme S
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TBC1D17 TBC1 domain family, member 17
TRA2B transformer 2 beta homolog (Drosophila)
TSC22D2 TSC22 domain family, member 2
TSGA10 testis specific, 10
TTLL5 tubulin tyrosine ligase-like family member 5
USP34 ubiquitin specific peptidase 34
VASP vasodilator-stimulated phosphoprotein
VCPIP1 valosin containing protein (p97)/p47 complex interacting protein 1
VPS53 vacuolar protein sorting 53 homolog (S. cerevisiae)
YY1 YY1 transcription factor
ZBTB48 zinc finger and BTB domain containing 48
ZNF286A zinc finger protein 286A

decreased expression

Symbol Name
ARHGAP10 Rho GTPase activating protein 10
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ARL15 ADP-ribosylation factor-like 15
ARMC7 armadillo repeat containing 7
ATG16L1 autophagy related 16-like 1 (S. cerevisiae)
ATP13A2 ATPase type 13A2
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
AZI2 5-azacytidine induced 2
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BATF basic leucine zipper transcription factor, ATF-like
BCL9 B-cell CLL/lymphoma 9
C14ORF93 chromosome 14 open reading frame 93
C5AR2 complement component 5a receptor 2
CAMTA2 calmodulin binding transcription activator 2
CAPG capping protein (actin filament), gelsolin-like
CASP3 caspase 3, apoptosis-related cysteine peptidase
CDKL3 cyclin-dependent kinase-like 3
CRLF1 cytokine receptor-like factor 1
CTC1 CTS telomere maintenance complex component 1
CTNNBIP1 catenin, beta interacting protein 1
CXORF56 chromosome X open reading frame 56
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DNM1 dynamin 1
EFCAB2 EF-hand calcium binding domain 2
EFNA3 ephrin-A3
ERMAP erythroblast membrane-associated protein (Scianna blood group)
EXO5 exonuclease 5
FKBP1B FK506 binding protein 1B, 12.6 kDa
FLT4 fms-related tyrosine kinase 4
FOXRED2 FAD-dependent oxidoreductase domain containing 2
GID4 GID complex subunit 4
GPRASP1 G protein-coupled receptor associated sorting protein 1
GUCY1B2 guanylate cyclase 1, soluble, beta 2 (pseudogene)
HGSNAT heparan-alpha-glucosaminide N-acetyltransferase
HINFP histone H4 transcription factor
HIRA histone cell cycle regulator
IGSF1 immunoglobulin superfamily, member 1
IL4R interleukin 4 receptor
INPP5B inositol polyphosphate-5-phosphatase, 75kDa
ITPKB inositol-trisphosphate 3-kinase B
KCNF1 potassium channel, voltage gated modifier subfamily F, member 1
KCNK15 potassium channel, two pore domain subfamily K, member 15
KCTD7 potassium channel tetramerization domain containing 7
KDM7A lysine (K)-specific demethylase 7A
KIAA0125 KIAA0125
KIAA0319L KIAA0319-like
KREMEN2 kringle containing transmembrane protein 2
LRFN4 leucine rich repeat and fibronectin type III domain containing 4
LRP3 low density lipoprotein receptor-related protein 3
LRP5L low density lipoprotein receptor-related protein 5-like
MAFB v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog B
MARK4 MAP/microtubule affinity-regulating kinase 4
MRPL52 mitochondrial ribosomal protein L52
MT1H metallothionein 1H
MYO1F myosin IF
NPM3 nucleophosmin/nucleoplasmin 3
NR1H3 nuclear receptor subfamily 1, group H, member 3
OSMR oncostatin M receptor
PCDHB8 protocadherin beta 8
PDK1 pyruvate dehydrogenase kinase, isozyme 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRPH peripherin
PRRG2 proline rich Gla (G-carboxyglutamic acid) 2
PTDSS2 phosphatidylserine synthase 2
QSER1 glutamine and serine rich 1
RASAL1 RAS protein activator like 1 (GAP1 like)
RNF123 ring finger protein 123
RNF31 ring finger protein 31
SCML2 sex comb on midleg-like 2 (Drosophila)
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SLC12A8 solute carrier family 12, member 8
SLC47A1 solute carrier family 47 (multidrug and toxin extrusion), member 1
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SNIP1 Smad nuclear interacting protein 1
SOX3 SRY (sex determining region Y)-box 3
SPHK1 sphingosine kinase 1
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STARD13 StAR-related lipid transfer (START) domain containing 13
SUN2 Sad1 and UNC84 domain containing 2
TAGLN transgelin
TAP1 transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
TM6SF1 transmembrane 6 superfamily member 1
TMC5 transmembrane channel-like 5
TMSB15A thymosin beta 15a
TNS2 tensin 2
TUBA3C tubulin, alpha 3c
USP20 ubiquitin specific peptidase 20
USP5 ubiquitin specific peptidase 5 (isopeptidase T)
VAX2 ventral anterior homeobox 2
XYLT2 xylosyltransferase II
ZBTB39 zinc finger and BTB domain containing 39
ZMYM3 zinc finger, MYM-type 3
ZNF134 zinc finger protein 134
ZNF442 zinc finger protein 442
ZNF532 zinc finger protein 532
ZSCAN2 zinc finger and SCAN domain containing 2