sulconazole-4998 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

197 genes differentially expressed following the sulconazole-4998 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AKR1C1 aldo-keto reductase family 1, member C1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ALDOB aldolase B, fructose-bisphosphate
AMPD1 adenosine monophosphate deaminase 1
ATF3 activating transcription factor 3
ATN1 atrophin 1
ATP8B2 ATPase, aminophospholipid transporter, class I, type 8B, member 2
BHLHE40 basic helix-loop-helix family, member e40
C10ORF95 chromosome 10 open reading frame 95
C3ORF18 chromosome 3 open reading frame 18
CASP1 caspase 1, apoptosis-related cysteine peptidase
CCDC7 coiled-coil domain containing 7
CEMIP cell migration inducing protein, hyaluronan binding
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CNN3 calponin 3, acidic
DDIT3 DNA-damage-inducible transcript 3
DDIT4 DNA-damage-inducible transcript 4
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
DHRS3 dehydrogenase/reductase (SDR family) member 3
DNAJA4 DnaJ (Hsp40) homolog, subfamily A, member 4
EGR1 early growth response 1
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2
FAM46C family with sequence similarity 46, member C
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
FGD1 FYVE, RhoGEF and PH domain containing 1
FGF16 fibroblast growth factor 16
FLJ11292
FLOT1 flotillin 1
FOS FBJ murine osteosarcoma viral oncogene homolog
FRMD4B FERM domain containing 4B
GBP1 guanylate binding protein 1, interferon-inducible
GEM GTP binding protein overexpressed in skeletal muscle
GUK1 guanylate kinase 1
HBEGF heparin-binding EGF-like growth factor
HCAR3 hydroxycarboxylic acid receptor 3
HERC5 HECT and RLD domain containing E3 ubiquitin protein ligase 5
HIST1H1T histone cluster 1, H1t
HIST1H2BJ histone cluster 1, H2bj
HIST1H2BO histone cluster 1, H2bo
HIST1H4F histone cluster 1, H4f
HIST2H2AA3 histone cluster 2, H2aa3
HMOX1 heme oxygenase 1
HSD17B14 hydroxysteroid (17-beta) dehydrogenase 14
HSPA6 heat shock 70kDa protein 6 (HSP70B')
IFIT1 interferon-induced protein with tetratricopeptide repeats 1
IFIT2 interferon-induced protein with tetratricopeptide repeats 2
INHBA inhibin, beta A
INHBE inhibin, beta E
JUN jun proto-oncogene
KCNMA1 potassium channel, calcium activated large conductance subfamily M alpha, member 1
KLF2 Kruppel-like factor 2
KLF6 Kruppel-like factor 6
LRRN3 leucine rich repeat neuronal 3
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP3K12 mitogen-activated protein kinase kinase kinase 12
MED25 mediator complex subunit 25
METTL7A methyltransferase like 7A
MID1 midline 1
MIER2 mesoderm induction early response 1, family member 2
NAALAD2 N-acetylated alpha-linked acidic dipeptidase 2
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NOL12 nucleolar protein 12
NOP16 NOP16 nucleolar protein
NR1H4 nuclear receptor subfamily 1, group H, member 4
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAS1 2'-5'-oligoadenylate synthetase 1, 40/46kDa
OASL 2'-5'-oligoadenylate synthetase-like
OR52A1 olfactory receptor, family 52, subfamily A, member 1
P2RY13 purinergic receptor P2Y, G-protein coupled, 13
PAX2 paired box 2
PDE4C phosphodiesterase 4C, cAMP-specific
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
PPT2 palmitoyl-protein thioesterase 2
RND1 Rho family GTPase 1
RPL35A ribosomal protein L35a
S100A8 S100 calcium binding protein A8
SEMA3B sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
SLC1A4 solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC7A11 solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11
SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8
SNCG synuclein, gamma (breast cancer-specific protein 1)
SOD2 superoxide dismutase 2, mitochondrial
SOX15 SRY (sex determining region Y)-box 15
SOX9 SRY (sex determining region Y)-box 9
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
THRB thyroid hormone receptor, beta
TNFAIP3 tumor necrosis factor, alpha-induced protein 3
TRA T cell receptor alpha locus
TRIO trio Rho guanine nucleotide exchange factor
UTS2 urotensin 2
VAV2 vav 2 guanine nucleotide exchange factor
VN1R1 vomeronasal 1 receptor 1
VPS13B vacuolar protein sorting 13 homolog B (yeast)
WIPI2 WD repeat domain, phosphoinositide interacting 2
ZFP36L2 ZFP36 ring finger protein-like 2
ZNF254 zinc finger protein 254

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
AAAS achalasia, adrenocortical insufficiency, alacrimia
ACIN1 apoptotic chromatin condensation inducer 1
ACYP1 acylphosphatase 1, erythrocyte (common) type
ADGRE5 adhesion G protein-coupled receptor E5
ALKBH4 alkB, alkylation repair homolog 4 (E. coli)
ANXA2P3 annexin A2 pseudogene 3
APBB3 amyloid beta (A4) precursor protein-binding, family B, member 3
AXIN1 axin 1
BAHD1 bromo adjacent homology domain containing 1
BCCIP BRCA2 and CDKN1A interacting protein
BCL9 B-cell CLL/lymphoma 9
C10ORF88 chromosome 10 open reading frame 88
C11ORF68 chromosome 11 open reading frame 68
C22ORF29 chromosome 22 open reading frame 29
C4ORF29 chromosome 4 open reading frame 29
CASZ1 castor zinc finger 1
CBX7 chromobox homolog 7
CD82 CD82 molecule
CDC37 cell division cycle 37
CHML choroideremia-like (Rab escort protein 2)
CHMP7 charged multivesicular body protein 7
CMAS cytidine monophosphate N-acetylneuraminic acid synthetase
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DDB1 damage-specific DNA binding protein 1, 127kDa
DGCR11 DiGeorge syndrome critical region gene 11 (non-protein coding)
DOCK4 dedicator of cytokinesis 4
EFNA3 ephrin-A3
ELMO3 engulfment and cell motility 3
ENTPD5 ectonucleoside triphosphate diphosphohydrolase 5
FER fer (fps/fes related) tyrosine kinase
FMO4 flavin containing monooxygenase 4
FSTL3 follistatin-like 3 (secreted glycoprotein)
GALNT12 polypeptide N-acetylgalactosaminyltransferase 12
GALNT14 polypeptide N-acetylgalactosaminyltransferase 14
GLCE glucuronic acid epimerase
HELZ helicase with zinc finger
HRAS Harvey rat sarcoma viral oncogene homolog
INO80D INO80 complex subunit D
IPO13 importin 13
KRT8P12 keratin 8 pseudogene 12
LHX6 LIM homeobox 6
LOC257152 uncharacterized LOC257152
LSM7 LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
MALL mal, T-cell differentiation protein-like
MAPKBP1 mitogen-activated protein kinase binding protein 1
METTL16 methyltransferase like 16
METTL21B methyltransferase like 21B
MFSD11 major facilitator superfamily domain containing 11
MNS1 meiosis-specific nuclear structural 1
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa
NFE2L3 nuclear factor, erythroid 2-like 3
NME5 NME/NM23 family member 5
NPM3 nucleophosmin/nucleoplasmin 3
NPY1R neuropeptide Y receptor Y1
NUP62CL nucleoporin 62kDa C-terminal like
OLFML3 olfactomedin-like 3
OTUD3 OTU deubiquitinase 3
PAQR6 progestin and adipoQ receptor family member VI
PCSK7 proprotein convertase subtilisin/kexin type 7
PLD3 phospholipase D family, member 3
PODXL2 podocalyxin-like 2
POLA2 polymerase (DNA directed), alpha 2, accessory subunit
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1
PPM1F protein phosphatase, Mg2+/Mn2+ dependent, 1F
PRICKLE3 prickle homolog 3 (Drosophila)
PTTG3P pituitary tumor-transforming 3, pseudogene
PVRL2 poliovirus receptor-related 2 (herpesvirus entry mediator B)
RAB3A RAB3A, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RASSF8 Ras association (RalGDS/AF-6) domain family (N-terminal) member 8
RPAP1 RNA polymerase II associated protein 1
RPGR retinitis pigmentosa GTPase regulator
RPGRIP1L RPGRIP1-like
SCRN3 secernin 3
SGTA small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC9A1 solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1
SMEK2 SMEK homolog 2, suppressor of mek1 (Dictyostelium)
SRD5A3 steroid 5 alpha-reductase 3
SUZ12P1 suppressor of zeste 12 homolog pseudogene 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCTN1 tectonic family member 1
TESK1 testis-specific kinase 1
TIMM50 translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
TMEM30A transmembrane protein 30A
TPCN1 two pore segment channel 1
TUBA3D tubulin, alpha 3d
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
USP18 ubiquitin specific peptidase 18
WBP2 WW domain binding protein 2
WDR25 WD repeat domain 25
ZBTB48 zinc finger and BTB domain containing 48
ZNF180 zinc finger protein 180
ZNF573 zinc finger protein 573
ZNF639 zinc finger protein 639
ZNF85 zinc finger protein 85