succinylsulfathiazole-4847 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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200 genes differentially expressed following the succinylsulfathiazole-4847 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AATK apoptosis-associated tyrosine kinase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ADAM22 ADAM metallopeptidase domain 22
ADAMTS7 ADAM metallopeptidase with thrombospondin type 1 motif, 7
AHI1 Abelson helper integration site 1
ARID4B AT rich interactive domain 4B (RBP1-like)
AZGP1 alpha-2-glycoprotein 1, zinc-binding
BACH1 BTB and CNC homology 1, basic leucine zipper transcription factor 1
BEST2 bestrophin 2
BTF3P11 basic transcription factor 3 pseudogene 11
CASP2 caspase 2, apoptosis-related cysteine peptidase
CD6 CD6 molecule
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CEND1 cell cycle exit and neuronal differentiation 1
CEP250 centrosomal protein 250kDa
CFHR2 complement factor H-related 2
CLCA1 chloride channel accessory 1
COMT catechol-O-methyltransferase
CUL7 cullin 7
CXCR4 chemokine (C-X-C motif) receptor 4
DOCK5 dedicator of cytokinesis 5
DPF3 D4, zinc and double PHD fingers, family 3
DRD2 dopamine receptor D2
EGFR epidermal growth factor receptor
ELSPBP1 epididymal sperm binding protein 1
EMP1 epithelial membrane protein 1
ENPP4 ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
ETV4 ets variant 4
FMOD fibromodulin
FOXH1 forkhead box H1
FRMD1 FERM domain containing 1
GIF gastric intrinsic factor (vitamin B synthesis)
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPC3 glypican 3
GSTA3 glutathione S-transferase alpha 3
HAPLN1 hyaluronan and proteoglycan link protein 1
HESX1 HESX homeobox 1
HIST1H1T histone cluster 1, H1t
HIST1H2BM histone cluster 1, H2bm
HOXA4 homeobox A4
HTR3B 5-hydroxytryptamine (serotonin) receptor 3B, ionotropic
IDS iduronate 2-sulfatase
IGLL3P immunoglobulin lambda-like polypeptide 3, pseudogene
IL1RN interleukin 1 receptor antagonist
INHBE inhibin, beta E
INSR insulin receptor
ITGAL integrin, alpha L (antigen CD11A (p180), lymphocyte function-associated antigen 1; alpha polypeptide)
ITIH2 inter-alpha-trypsin inhibitor heavy chain 2
KCND3 potassium channel, voltage gated Shal related subfamily D, member 3
KDM8 lysine (K)-specific demethylase 8
KHK ketohexokinase (fructokinase)
KRT6B keratin 6B, type II
LLPH LLP homolog, long-term synaptic facilitation (Aplysia)
LMOD1 leiomodin 1 (smooth muscle)
MMP13 matrix metallopeptidase 13
MMP3 matrix metallopeptidase 3
MST1 macrophage stimulating 1
MTHFR methylenetetrahydrofolate reductase (NAD(P)H)
MTMR3 myotubularin related protein 3
NCR2 natural cytotoxicity triggering receptor 2
NFATC1 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
OR1G1 olfactory receptor, family 1, subfamily G, member 1
OSBPL10 oxysterol binding protein-like 10
PARVA parvin, alpha
PDLIM5 PDZ and LIM domain 5
PIP prolactin-induced protein
PLCL2 phospholipase C-like 2
PPARG peroxisome proliferator-activated receptor gamma
PTCRA pre T-cell antigen receptor alpha
RAB23 RAB23, member RAS oncogene family
RARRES2 retinoic acid receptor responder (tazarotene induced) 2
RBFOX1 RNA binding protein, fox-1 homolog (C. elegans) 1
RCAN1 regulator of calcineurin 1
RUNX1 runt-related transcription factor 1
SC5D sterol-C5-desaturase
SCG2 secretogranin II
SCN11A sodium channel, voltage gated, type XI alpha subunit
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein
SIRT5 sirtuin 5
SLAMF7 SLAM family member 7
SLC22A14 solute carrier family 22, member 14
SLC30A3 solute carrier family 30 (zinc transporter), member 3
SLC4A4 solute carrier family 4 (sodium bicarbonate cotransporter), member 4
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SPON1 spondin 1, extracellular matrix protein
STIM1 stromal interaction molecule 1
STS steroid sulfatase (microsomal), isozyme S
SULT1B1 sulfotransferase family, cytosolic, 1B, member 1
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TBCD tubulin folding cofactor D
TBL2 transducin (beta)-like 2
TCL6 T-cell leukemia/lymphoma 6 (non-protein coding)
THPO thrombopoietin
THTPA thiamine triphosphatase
TPMT thiopurine S-methyltransferase
TRAF3IP1 TNF receptor-associated factor 3 interacting protein 1
TRIM21 tripartite motif containing 21
VAMP1 vesicle-associated membrane protein 1 (synaptobrevin 1)
ZC3H13 zinc finger CCCH-type containing 13
ZNF771 zinc finger protein 771

decreased expression

Symbol Name
ACSF2 acyl-CoA synthetase family member 2
ADGRE5 adhesion G protein-coupled receptor E5
ADM adrenomedullin
ANKRD27 ankyrin repeat domain 27 (VPS9 domain)
ANKRD36 ankyrin repeat domain 36
ANXA1 annexin A1
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma
ARID3B AT rich interactive domain 3B (BRIGHT-like)
ARRB2 arrestin, beta 2
ATAD5 ATPase family, AAA domain containing 5
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1
CAD carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
CCDC186 coiled-coil domain containing 186
CCDC85C coiled-coil domain containing 85C
CCDC88C coiled-coil domain containing 88C
CCT6B chaperonin containing TCP1, subunit 6B (zeta 2)
CD2AP CD2-associated protein
CDC37 cell division cycle 37
CFAP44 cilia and flagella associated protein 44
CGREF1 cell growth regulator with EF-hand domain 1
CHRM3 cholinergic receptor, muscarinic 3
COPZ2 coatomer protein complex, subunit zeta 2
CRABP1 cellular retinoic acid binding protein 1
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
DFFB DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)
DHRS11 dehydrogenase/reductase (SDR family) member 11
DSCAM Down syndrome cell adhesion molecule
ERCC5 excision repair cross-complementation group 5
ESRP2 epithelial splicing regulatory protein 2
FADS2 fatty acid desaturase 2
FAM53B family with sequence similarity 53, member B
FLT4 fms-related tyrosine kinase 4
FURIN furin (paired basic amino acid cleaving enzyme)
GABPA GA binding protein transcription factor, alpha subunit 60kDa
GBP2 guanylate binding protein 2, interferon-inducible
GMCL1 germ cell-less, spermatogenesis associated 1
GTF2A1 general transcription factor IIA, 1, 19/37kDa
JUNB jun B proto-oncogene
KAZALD1 Kazal-type serine peptidase inhibitor domain 1
KIAA0895 KIAA0895
KRT8P12 keratin 8 pseudogene 12
LRCH3 leucine-rich repeats and calponin homology (CH) domain containing 3
LSM14B LSM14B, SCD6 homolog B (S. cerevisiae)
LYRM9 LYR motif containing 9
MAMLD1 mastermind-like domain containing 1
MAP4K3 mitogen-activated protein kinase kinase kinase kinase 3
MBOAT2 membrane bound O-acyltransferase domain containing 2
MEFV Mediterranean fever
MVD mevalonate (diphospho) decarboxylase
NDUFAF7 NADH dehydrogenase (ubiquinone) complex I, assembly factor 7
NIPAL2 NIPA-like domain containing 2
NOD1 nucleotide-binding oligomerization domain containing 1
NRSN2 neurensin 2
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PACS1 phosphofurin acidic cluster sorting protein 1
PBLD phenazine biosynthesis-like protein domain containing
PC pyruvate carboxylase
PER3 period circadian clock 3
PHC1 polyhomeotic homolog 1 (Drosophila)
PIM2 Pim-2 proto-oncogene, serine/threonine kinase
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent)
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
PRKX protein kinase, X-linked
PROCR protein C receptor, endothelial
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
PYCRL pyrroline-5-carboxylate reductase-like
RAB11FIP5 RAB11 family interacting protein 5 (class I)
RAD54L2 RAD54-like 2 (S. cerevisiae)
RFWD3 ring finger and WD repeat domain 3
RHBDF2 rhomboid 5 homolog 2 (Drosophila)
RHPN1-AS1 RHPN1 antisense RNA 1 (head to head)
RPL10L ribosomal protein L10-like
RPS6KC1 ribosomal protein S6 kinase, 52kDa, polypeptide 1
SAV1 salvador family WW domain containing protein 1
SCGB2A2 secretoglobin, family 2A, member 2
SCHIP1 schwannomin interacting protein 1
SH2D4A SH2 domain containing 4A
SKA1 spindle and kinetochore associated complex subunit 1
SLC12A5 solute carrier family 12 (potassium/chloride transporter), member 5
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SMC6 structural maintenance of chromosomes 6
SMG1 SMG1 phosphatidylinositol 3-kinase-related kinase
SMIM14 small integral membrane protein 14
SNORA21 small nucleolar RNA, H/ACA box 21
SPIDR scaffolding protein involved in DNA repair
SPINK5 serine peptidase inhibitor, Kazal type 5
TCTN2 tectonic family member 2
TESC tescalcin
THYN1 thymocyte nuclear protein 1
TMEM184C transmembrane protein 184C
TTC4 tetratricopeptide repeat domain 4
UAP1L1 UDP-N-acetylglucosamine pyrophosphorylase 1 like 1
UBQLN4 ubiquilin 4
ZBED8 zinc finger, BED-type containing 8
ZC3H12A zinc finger CCCH-type containing 12A
ZNF219 zinc finger protein 219
ZNF573 zinc finger protein 573
ZNF675 zinc finger protein 675
ZNF7 zinc finger protein 7