strophanthidin-7182 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the strophanthidin-7182 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
AAGAB alpha- and gamma-adaptin binding protein
ADCY6 adenylate cyclase 6
AK1 adenylate kinase 1
AKR1C2 aldo-keto reductase family 1, member C2
ARC activity-regulated cytoskeleton-associated protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
BLVRA biliverdin reductase A
BRF2 BRF2, RNA polymerase III transcription initiation factor 50 kDa subunit
CCNK cyclin K
CDC14A cell division cycle 14A
CEP104 centrosomal protein 104kDa
CLDN9 claudin 9
CLUAP1 clusterin associated protein 1
COPS8 COP9 signalosome subunit 8
COQ7 coenzyme Q7 homolog, ubiquinone (yeast)
CPD carboxypeptidase D
CRYBG3 beta-gamma crystallin domain containing 3
CYHR1 cysteine/histidine-rich 1
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1
CYP27B1 cytochrome P450, family 27, subfamily B, polypeptide 1
DAPK2 death-associated protein kinase 2
DDX58 DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
DRD1 dopamine receptor D1
DSCAM Down syndrome cell adhesion molecule
DXO decapping exoribonuclease
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EMC1 ER membrane protein complex subunit 1
ESR1 estrogen receptor 1
EXOC5 exocyst complex component 5
EXTL3 exostosin-like glycosyltransferase 3
GLRX glutaredoxin (thioltransferase)
GNB1L guanine nucleotide binding protein (G protein), beta polypeptide 1-like
HIST1H2BC histone cluster 1, H2bc
HIST1H4F histone cluster 1, H4f
HNMT histamine N-methyltransferase
HOXA10 homeobox A10
IFT122 intraflagellar transport 122
ITGA6 integrin, alpha 6
KCNIP1 Kv channel interacting protein 1
KIAA0485 uncharacterized LOC57235
LACTB2 lactamase, beta 2
LIG3 ligase III, DNA, ATP-dependent
LTBP2 latent transforming growth factor beta binding protein 2
LYPD1 LY6/PLAUR domain containing 1
MAPK11 mitogen-activated protein kinase 11
MBNL3 muscleblind-like splicing regulator 3
MED28 mediator complex subunit 28
MFSD11 major facilitator superfamily domain containing 11
MYO9B myosin IXB
NACA2 nascent polypeptide-associated complex alpha subunit 2
NCOA2 nuclear receptor coactivator 2
PACS1 phosphofurin acidic cluster sorting protein 1
PAICS phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase
PAPOLA poly(A) polymerase alpha
PARD6B par-6 family cell polarity regulator beta
PCDHA6 protocadherin alpha 6
PDE6B phosphodiesterase 6B, cGMP-specific, rod, beta
PFDN6 prefoldin subunit 6
PHC1 polyhomeotic homolog 1 (Drosophila)
PPP2R3B protein phosphatase 2, regulatory subunit B'', beta
PRODH proline dehydrogenase (oxidase) 1
PTK6 protein tyrosine kinase 6
PTPRF protein tyrosine phosphatase, receptor type, F
PXN paxillin
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RBBP9 retinoblastoma binding protein 9
RBM34 RNA binding motif protein 34
RCAN1 regulator of calcineurin 1
RER1 retention in endoplasmic reticulum sorting receptor 1
RNASEH2B ribonuclease H2, subunit B
RPL23AP32 ribosomal protein L23a pseudogene 32
SC5D sterol-C5-desaturase
SECTM1 secreted and transmembrane 1
SEMA4D sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
SETD1B SET domain containing 1B
SFXN3 sideroflexin 3
SGCD sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
SKIL SKI-like proto-oncogene
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC26A2 solute carrier family 26 (anion exchanger), member 2
SLC29A1 solute carrier family 29 (equilibrative nucleoside transporter), member 1
SLC35A3 solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
SLC6A6 solute carrier family 6 (neurotransmitter transporter), member 6
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa
SP100 SP100 nuclear antigen
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
TAF1 TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
TMEM19 transmembrane protein 19
TMEM63A transmembrane protein 63A
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TRAF3 TNF receptor-associated factor 3
TROVE2 TROVE domain family, member 2
VARS valyl-tRNA synthetase
ZAK sterile alpha motif and leucine zipper containing kinase AZK
ZBTB14 zinc finger and BTB domain containing 14
ZMIZ2 zinc finger, MIZ-type containing 2
ZMYND11 zinc finger, MYND-type containing 11
ZNF696 zinc finger protein 696
ZNF783 zinc finger family member 783

decreased expression

Symbol Name
ACVR2A activin A receptor, type IIA
AHDC1 AT hook, DNA binding motif, containing 1
ARHGEF1 Rho guanine nucleotide exchange factor (GEF) 1
BBS10 Bardet-Biedl syndrome 10
BBS7 Bardet-Biedl syndrome 7
BRAF B-Raf proto-oncogene, serine/threonine kinase
BTBD2 BTB (POZ) domain containing 2
BTF3P12 basic transcription factor 3 pseudogene 12
C19ORF40 chromosome 19 open reading frame 40
CCDC85C coiled-coil domain containing 85C
CDR2L cerebellar degeneration-related protein 2-like
CEP85 centrosomal protein 85kDa
CHIC2 cysteine-rich hydrophobic domain 2
CHKB choline kinase beta
CIC capicua transcriptional repressor
CIR1 corepressor interacting with RBPJ, 1
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
CNGB3 cyclic nucleotide gated channel beta 3
CNKSR1 connector enhancer of kinase suppressor of Ras 1
CNPY3 canopy FGF signaling regulator 3
CTAGE9 CTAGE family, member 9
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DHX35 DEAH (Asp-Glu-Ala-His) box polypeptide 35
DIP2A DIP2 disco-interacting protein 2 homolog A (Drosophila)
EIF5A2 eukaryotic translation initiation factor 5A2
ETAA1 Ewing tumor-associated antigen 1
FBXO31 F-box protein 31
FLCN folliculin
FURIN furin (paired basic amino acid cleaving enzyme)
GAREM GRB2 associated, regulator of MAPK1
GLI3 GLI family zinc finger 3
GNL1 guanine nucleotide binding protein-like 1
H2AFY2 H2A histone family, member Y2
HINFP histone H4 transcription factor
ICK intestinal cell (MAK-like) kinase
IDI2-AS1 IDI2 antisense RNA 1
IRF2BP1 interferon regulatory factor 2 binding protein 1
JADE1 jade family PHD finger 1
KDM5C lysine (K)-specific demethylase 5C
KIFC1 kinesin family member C1
KREMEN2 kringle containing transmembrane protein 2
LIN7B lin-7 homolog B (C. elegans)
LINS lines homolog (Drosophila)
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MFSD12 major facilitator superfamily domain containing 12
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MNAT1 MNAT CDK-activating kinase assembly factor 1
MON1B MON1 secretory trafficking family member B
MOSPD3 motile sperm domain containing 3
MRPL2 mitochondrial ribosomal protein L2
MUL1 mitochondrial E3 ubiquitin protein ligase 1
MUM1 melanoma associated antigen (mutated) 1
MVD mevalonate (diphospho) decarboxylase
NBAS neuroblastoma amplified sequence
NPM3 nucleophosmin/nucleoplasmin 3
NRGN neurogranin (protein kinase C substrate, RC3)
PAQR6 progestin and adipoQ receptor family member VI
PCDHB3 protocadherin beta 3
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PISD phosphatidylserine decarboxylase
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific)
PLCXD1 phosphatidylinositol-specific phospholipase C, X domain containing 1
PLEKHM2 pleckstrin homology domain containing, family M (with RUN domain) member 2
POLR1B polymerase (RNA) I polypeptide B, 128kDa
PRSS22 protease, serine, 22
PTTG3P pituitary tumor-transforming 3, pseudogene
RAB3IL1 RAB3A interacting protein (rabin3)-like 1
RIBC2 RIB43A domain with coiled-coils 2
RNF123 ring finger protein 123
ROM1 retinal outer segment membrane protein 1
RPRM reprimo, TP53 dependent G2 arrest mediator candidate
RWDD2A RWD domain containing 2A
SAMHD1 SAM domain and HD domain 1
SCD5 stearoyl-CoA desaturase 5
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC26A6 solute carrier family 26 (anion exchanger), member 6
SLC29A3 solute carrier family 29 (equilibrative nucleoside transporter), member 3
SOX12 SRY (sex determining region Y)-box 12
SOX3 SRY (sex determining region Y)-box 3
SPAG4 sperm associated antigen 4
STAG3 stromal antigen 3
TBX19 T-box 19
THBS3 thrombospondin 3
TLN1 talin 1
TLR5 toll-like receptor 5
TNRC6B trinucleotide repeat containing 6B
TRAIP TRAF interacting protein
TRAPPC12 trafficking protein particle complex 12
TRMT13 tRNA methyltransferase 13 homolog (S. cerevisiae)
TTC23 tetratricopeptide repeat domain 23
TUBGCP5 tubulin, gamma complex associated protein 5
USB1 U6 snRNA biogenesis 1
ZC3H12A zinc finger CCCH-type containing 12A
ZNF205 zinc finger protein 205
ZNF219 zinc finger protein 219
ZNF276 zinc finger protein 276
ZNF672 zinc finger protein 672