strophanthidin-6087 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the strophanthidin-6087 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADM adrenomedullin
AKAP8L A kinase (PRKA) anchor protein 8-like
AKAP9 A kinase (PRKA) anchor protein 9
AMOTL2 angiomotin like 2
ATF3 activating transcription factor 3
AVPI1 arginine vasopressin-induced 1
BCL6 B-cell CLL/lymphoma 6
BLZF1 basic leucine zipper nuclear factor 1
BTG1 B-cell translocation gene 1, anti-proliferative
CCNG2 cyclin G2
CDK19 cyclin-dependent kinase 19
CLDN1 claudin 1
CLK1 CDC-like kinase 1
CLK4 CDC-like kinase 4
CTGF connective tissue growth factor
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1
CYR61 cysteine-rich, angiogenic inducer, 61
DES desmin
DLX2 distal-less homeobox 2
DUSP1 dual specificity phosphatase 1
DUSP4 dual specificity phosphatase 4
EDN1 endothelin 1
EDRF1 erythroid differentiation regulatory factor 1
EED embryonic ectoderm development
EFNA1 ephrin-A1
EGR1 early growth response 1
EHD1 EH-domain containing 1
EPHA2 EPH receptor A2
ERBB3 erb-b2 receptor tyrosine kinase 3
FAM46A family with sequence similarity 46, member A
FOS FBJ murine osteosarcoma viral oncogene homolog
GEM GTP binding protein overexpressed in skeletal muscle
GPRC5A G protein-coupled receptor, class C, group 5, member A
HBP1 HMG-box transcription factor 1
HIC2 hypermethylated in cancer 2
HIST1H1T histone cluster 1, H1t
HIST1H4C histone cluster 1, H4c
HNRNPD heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
HOXC13 homeobox C13
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
ID3 inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein
IER2 immediate early response 2
IL6 interleukin 6
IP6K2 inositol hexakisphosphate kinase 2
IRS2 insulin receptor substrate 2
JUN jun proto-oncogene
KLF10 Kruppel-like factor 10
KLF6 Kruppel-like factor 6
KLHL20 kelch-like family member 20
KLHL24 kelch-like family member 24
LDLR low density lipoprotein receptor
LINS lines homolog (Drosophila)
LRRTM2 leucine rich repeat transmembrane neuronal 2
MAFF v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F
MAP2K7 mitogen-activated protein kinase kinase 7
MAPK8 mitogen-activated protein kinase 8
MCL1 myeloid cell leukemia 1
MXD1 MAX dimerization protein 1
NACA nascent polypeptide-associated complex alpha subunit
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFIB nuclear factor I/B
NR3C1 nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
NR4A2 nuclear receptor subfamily 4, group A, member 2
NR4A3 nuclear receptor subfamily 4, group A, member 3
OR2B6 olfactory receptor, family 2, subfamily B, member 6
OVOL1 ovo-like zinc finger 1
PDP1 pyruvate dehyrogenase phosphatase catalytic subunit 1
PNRC1 proline-rich nuclear receptor coactivator 1
PPP1R15A protein phosphatase 1, regulatory subunit 15A
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RGS16 regulator of G-protein signaling 16
RHOBTB3 Rho-related BTB domain containing 3
RMND5A required for meiotic nuclear division 5 homolog A (S. cerevisiae)
RSRC2 arginine/serine-rich coiled-coil 2
SBNO1 strawberry notch homolog 1 (Drosophila)
SCUBE3 signal peptide, CUB domain, EGF-like 3
SERTAD3 SERTA domain containing 3
SGPP1 sphingosine-1-phosphate phosphatase 1
SKIL SKI-like proto-oncogene
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SPTAN1 spectrin, alpha, non-erythrocytic 1
SRCAP Snf2-related CREBBP activator protein
STX3 syntaxin 3
TCF25 transcription factor 25 (basic helix-loop-helix)
TGFB2 transforming growth factor, beta 2
TXNIP thioredoxin interacting protein
UBE2H ubiquitin-conjugating enzyme E2H
WDR33 WD repeat domain 33
ZBTB40 zinc finger and BTB domain containing 40
ZFAND6 zinc finger, AN1-type domain 6
ZMYM2 zinc finger, MYM-type 2
ZNF335 zinc finger protein 335
ZNF654 zinc finger protein 654
ZNF750 zinc finger protein 750

decreased expression

Symbol Name
ADAT1 adenosine deaminase, tRNA-specific 1
ANKRD46 ankyrin repeat domain 46
ANKZF1 ankyrin repeat and zinc finger domain containing 1
ARMCX1 armadillo repeat containing, X-linked 1
ASB13 ankyrin repeat and SOCS box containing 13
ATP13A2 ATPase type 13A2
BBS10 Bardet-Biedl syndrome 10
BCL9 B-cell CLL/lymphoma 9
C11ORF71 chromosome 11 open reading frame 71
C5ORF45 chromosome 5 open reading frame 45
C9ORF40 chromosome 9 open reading frame 40
CAMTA1 calmodulin binding transcription activator 1
CBR3 carbonyl reductase 3
CBX7 chromobox homolog 7
CDKN2C cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
CHAC1 ChaC glutathione-specific gamma-glutamylcyclotransferase 1
CLCN5 chloride channel, voltage-sensitive 5
DEAF1 DEAF1 transcription factor
DET1 de-etiolated homolog 1 (Arabidopsis)
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DTX4 deltex 4, E3 ubiquitin ligase
EAF2 ELL associated factor 2
EEF2KMT eukaryotic elongation factor 2 lysine methyltransferase
EHD3 EH-domain containing 3
EIF2B3 eukaryotic translation initiation factor 2B, subunit 3 gamma, 58kDa
FADD Fas (TNFRSF6)-associated via death domain
FAM86B1 family with sequence similarity 86, member B1
FAM86C1 family with sequence similarity 86, member C1
FANCF Fanconi anemia, complementation group F
GEMIN4 gem (nuclear organelle) associated protein 4
GEMIN6 gem (nuclear organelle) associated protein 6
GPR19 G protein-coupled receptor 19
GTF2E1 general transcription factor IIE, polypeptide 1, alpha 56kDa
H2AFY2 H2A histone family, member Y2
HIRIP3 HIRA interacting protein 3
HPS5 Hermansky-Pudlak syndrome 5
HPS6 Hermansky-Pudlak syndrome 6
HSPBAP1 HSPB (heat shock 27kDa) associated protein 1
KRCC1 lysine-rich coiled-coil 1
LINC00339 long intergenic non-protein coding RNA 339
LOC100287590 uncharacterized LOC100287590
LRRC61 leucine rich repeat containing 61
MAP6D1 MAP6 domain containing 1
MKKS McKusick-Kaufman syndrome
MPPED2 metallophosphoesterase domain containing 2
NELFE negative elongation factor complex member E
NOL8 nucleolar protein 8
NUDT6 nudix (nucleoside diphosphate linked moiety X)-type motif 6
ORC3 origin recognition complex, subunit 3
OXSM 3-oxoacyl-ACP synthase, mitochondrial
PAAF1 proteasomal ATPase-associated factor 1
PAGR1 PAXIP1 associated glutamate-rich protein 1
PALB2 partner and localizer of BRCA2
PCF11 PCF11 cleavage and polyadenylation factor subunit
POGK pogo transposable element with KRAB domain
POLI polymerase (DNA directed) iota
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PRR15L proline rich 15-like
PRR3 proline rich 3
PTCD2 pentatricopeptide repeat domain 2
PUS7L pseudouridylate synthase 7 homolog (S. cerevisiae)-like
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RHOBTB1 Rho-related BTB domain containing 1
RIBC2 RIB43A domain with coiled-coils 2
RPP40 ribonuclease P/MRP 40kDa subunit
RSAD1 radical S-adenosyl methionine domain containing 1
RWDD3 RWD domain containing 3
S100PBP S100P binding protein
SLC1A5 solute carrier family 1 (neutral amino acid transporter), member 5
SLC25A28 solute carrier family 25 (mitochondrial iron transporter), member 28
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4
SOWAHC sosondowah ankyrin repeat domain family member C
STARD13 StAR-related lipid transfer (START) domain containing 13
STARD7 StAR-related lipid transfer (START) domain containing 7
TBC1D31 TBC1 domain family, member 31
TBCCD1 TBCC domain containing 1
TFB1M transcription factor B1, mitochondrial
THAP4 THAP domain containing 4
THYN1 thymocyte nuclear protein 1
TNFRSF21 tumor necrosis factor receptor superfamily, member 21
TRIM27 tripartite motif containing 27
TRMT1L tRNA methyltransferase 1 homolog (S. cerevisiae)-like
TSEN2 TSEN2 tRNA splicing endonuclease subunit
WDR3 WD repeat domain 3
WDR60 WD repeat domain 60
XBP1 X-box binding protein 1
ZBED1 zinc finger, BED-type containing 1
ZBED8 zinc finger, BED-type containing 8
ZBTB24 zinc finger and BTB domain containing 24
ZC3H4 zinc finger CCCH-type containing 4
ZFP69B ZFP69 zinc finger protein B
ZNF133 zinc finger protein 133
ZNF23 zinc finger protein 23
ZNF239 zinc finger protein 239
ZNF302 zinc finger protein 302
ZNF623 zinc finger protein 623
ZNF7 zinc finger protein 7
ZSCAN16 zinc finger and SCAN domain containing 16
ZSCAN9 zinc finger and SCAN domain containing 9