streptomycin-7194 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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195 genes differentially expressed following the streptomycin-7194 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ADCY6 adenylate cyclase 6
ADCY9 adenylate cyclase 9
AEN apoptosis enhancing nuclease
AKR1C2 aldo-keto reductase family 1, member C2
ANKMY1 ankyrin repeat and MYND domain containing 1
APC adenomatous polyposis coli
ARC activity-regulated cytoskeleton-associated protein
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATP2B4 ATPase, Ca++ transporting, plasma membrane 4
ATP7A ATPase, Cu++ transporting, alpha polypeptide
AVL9 AVL9 homolog (S. cerevisiase)
B9D2 B9 protein domain 2
BIRC3 baculoviral IAP repeat containing 3
BLZF1 basic leucine zipper nuclear factor 1
C17ORF75 chromosome 17 open reading frame 75
CASP2 caspase 2, apoptosis-related cysteine peptidase
CASP3 caspase 3, apoptosis-related cysteine peptidase
CASP9 caspase 9, apoptosis-related cysteine peptidase
CCNO cyclin O
CD44 CD44 molecule (Indian blood group)
CFLAR CASP8 and FADD-like apoptosis regulator
CLEC16A C-type lectin domain family 16, member A
CTNNBL1 catenin, beta like 1
CYP2A6 cytochrome P450, family 2, subfamily A, polypeptide 6
CYTH1 cytohesin 1
DPYSL4 dihydropyrimidinase-like 4
DYNC2H1 dynein, cytoplasmic 2, heavy chain 1
E2F4 E2F transcription factor 4, p107/p130-binding
ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1
EPN2 epsin 2
ESR1 estrogen receptor 1
EXTL3 exostosin-like glycosyltransferase 3
FAM65A family with sequence similarity 65, member A
FILIP1L filamin A interacting protein 1-like
FLT4 fms-related tyrosine kinase 4
GDPD5 glycerophosphodiester phosphodiesterase domain containing 5
GOLGA1 golgin A1
HIST1H2BC histone cluster 1, H2bc
HNRNPH1 heterogeneous nuclear ribonucleoprotein H1 (H)
HOXA6 homeobox A6
HP1BP3 heterochromatin protein 1, binding protein 3
IFT22 intraflagellar transport 22
INTS7 integrator complex subunit 7
IPW imprinted in Prader-Willi syndrome (non-protein coding)
ITGB4 integrin, beta 4
KLF6 Kruppel-like factor 6
KRT17 keratin 17, type I
LHX2 LIM homeobox 2
LOC257152 uncharacterized LOC257152
LRRC61 leucine rich repeat containing 61
LYPD1 LY6/PLAUR domain containing 1
MAX MYC associated factor X
MBD3 methyl-CpG binding domain protein 3
MBNL2 muscleblind-like splicing regulator 2
MET MET proto-oncogene, receptor tyrosine kinase
MGAT4A mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
MPZL2 myelin protein zero-like 2
MVK mevalonate kinase
NEAT1 nuclear paraspeckle assembly transcript 1 (non-protein coding)
NMT2 N-myristoyltransferase 2
NPL N-acetylneuraminate pyruvate lyase (dihydrodipicolinate synthase)
OR7E47P olfactory receptor, family 7, subfamily E, member 47 pseudogene
OSGEPL1 O-sialoglycoprotein endopeptidase-like 1
PEX11A peroxisomal biogenesis factor 11 alpha
PHF20 PHD finger protein 20
PMS2P2 postmeiotic segregation increased 2 pseudogene 2
PRLR prolactin receptor
PRRG1 proline rich Gla (G-carboxyglutamic acid) 1
PTBP3 polypyrimidine tract binding protein 3
PTGIS prostaglandin I2 (prostacyclin) synthase
PTPRU protein tyrosine phosphatase, receptor type, U
RHOQ ras homolog family member Q
RINT1 RAD50 interactor 1
RNFT1 ring finger protein, transmembrane 1
RPL7 ribosomal protein L7
RUFY3 RUN and FYVE domain containing 3
SAP30 Sin3A-associated protein, 30kDa
SCUBE2 signal peptide, CUB domain, EGF-like 2
SKIL SKI-like proto-oncogene
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SMC1A structural maintenance of chromosomes 1A
SMEK1 SMEK homolog 1, suppressor of mek1 (Dictyostelium)
SP100 SP100 nuclear antigen
TAF9B TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa
TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)
TJP3 tight junction protein 3
TMEM120B transmembrane protein 120B
TMEM70 transmembrane protein 70
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b
TOR1AIP1 torsin A interacting protein 1
TRIM3 tripartite motif containing 3
U2SURP U2 snRNP-associated SURP domain containing
WDR76 WD repeat domain 76
ZBTB7A zinc finger and BTB domain containing 7A
ZC3H7B zinc finger CCCH-type containing 7B
ZC3HAV1 zinc finger CCCH-type, antiviral 1
ZDHHC17 zinc finger, DHHC-type containing 17
ZNF468 zinc finger protein 468

decreased expression

Symbol Name
ACIN1 apoptotic chromatin condensation inducer 1
ALKBH1 alkB, alkylation repair homolog 1 (E. coli)
ALS2CL ALS2 C-terminal like
ATP7B ATPase, Cu++ transporting, beta polypeptide
BCL9 B-cell CLL/lymphoma 9
C21ORF91 chromosome 21 open reading frame 91
CA11 carbonic anhydrase XI
CCDC9 coiled-coil domain containing 9
CD82 CD82 molecule
CEP131 centrosomal protein 131kDa
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CYP20A1 cytochrome P450, family 20, subfamily A, polypeptide 1
DAPP1 dual adaptor of phosphotyrosine and 3-phosphoinositides
DEAF1 DEAF1 transcription factor
DGAT1 diacylglycerol O-acyltransferase 1
DNA2 DNA replication helicase/nuclease 2
DNAJC12 DnaJ (Hsp40) homolog, subfamily C, member 12
DNAJC17 DnaJ (Hsp40) homolog, subfamily C, member 17
DNAL4 dynein, axonemal, light chain 4
DZANK1 double zinc ribbon and ankyrin repeat domains 1
E2F3 E2F transcription factor 3
EPB41L5 erythrocyte membrane protein band 4.1 like 5
EPHA2 EPH receptor A2
FGF23 fibroblast growth factor 23
FKBPL FK506 binding protein like
FOSL1 FOS-like antigen 1
GPC3 glypican 3
GSTA4 glutathione S-transferase alpha 4
HIST1H2AI histone cluster 1, H2ai
IRF2BP1 interferon regulatory factor 2 binding protein 1
JMJD4 jumonji domain containing 4
KIAA0319L KIAA0319-like
KLK5 kallikrein-related peptidase 5
KRT31 keratin 31, type I
LOC390998 ribosomal protein L10 pseudogene
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
LYL1 lymphoblastic leukemia associated hematopoiesis regulator 1
MAP1S microtubule-associated protein 1S
MMP15 matrix metallopeptidase 15 (membrane-inserted)
MOSPD3 motile sperm domain containing 3
MPST mercaptopyruvate sulfurtransferase
MRPL2 mitochondrial ribosomal protein L2
MXD3 MAX dimerization protein 3
NEK11 NIMA-related kinase 11
PARP16 poly (ADP-ribose) polymerase family, member 16
PCDHA5 protocadherin alpha 5
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime
PELI1 pellino E3 ubiquitin protein ligase 1
PEX26 peroxisomal biogenesis factor 26
PGBD5 piggyBac transposable element derived 5
PGGT1B protein geranylgeranyltransferase type I, beta subunit
PICK1 protein interacting with PRKCA 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PLA2G3 phospholipase A2, group III
PLEKHO2 pleckstrin homology domain containing, family O member 2
PPT2 palmitoyl-protein thioesterase 2
PROL1 proline rich, lacrimal 1
PTCD2 pentatricopeptide repeat domain 2
PTPN9 protein tyrosine phosphatase, non-receptor type 9
PTTG3P pituitary tumor-transforming 3, pseudogene
PYGB phosphorylase, glycogen; brain
RAB33B RAB33B, member RAS oncogene family
RAB3A RAB3A, member RAS oncogene family
RAC3 ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
RARS arginyl-tRNA synthetase
RNF19B ring finger protein 19B
RPH3AL rabphilin 3A-like (without C2 domains)
SH2D4A SH2 domain containing 4A
SLC12A8 solute carrier family 12, member 8
SLC22A18AS solute carrier family 22 (organic cation transporter), member 18 antisense
SLC8B1 solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
SMA4 glucuronidase, beta pseudogene
SMARCAL1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
SSBP3 single stranded DNA binding protein 3
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
STAG3 stromal antigen 3
STRN striatin, calmodulin binding protein
TBX19 T-box 19
THNSL1 threonine synthase-like 1 (S. cerevisiae)
TLR5 toll-like receptor 5
TMEM104 transmembrane protein 104
TMEM183A transmembrane protein 183A
TNS2 tensin 2
TOM1 target of myb1 (chicken)
TRAF6 TNF receptor-associated factor 6, E3 ubiquitin protein ligase
TUBA3C tubulin, alpha 3c
TUBGCP5 tubulin, gamma complex associated protein 5
UBTD1 ubiquitin domain containing 1
USP36 ubiquitin specific peptidase 36
VPS9D1 VPS9 domain containing 1
WNT1 wingless-type MMTV integration site family, member 1
XAB2 XPA binding protein 2
ZNF180 zinc finger protein 180
ZNF219 zinc finger protein 219
ZNF282 zinc finger protein 282
ZNF432 zinc finger protein 432
ZNF701 zinc finger protein 701