stereocilium bundle Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description An actin-based, cross-linked cellular protrusion on the apical surface of auditory and vestibular hair cells. Stereocilium bundles act as mechanosensory organelles by responding to fluid motion or fluid pressure changes. (Gene Ontology, GO_0032421)
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Genes

171 proteins co-occuring with the stereocilium bundle cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CDH23 cadherin-related 23 2.74508
PCDH15 protocadherin-related 15 2.46139
MYO7A myosin VIIA 2.13622
ESPN espin 2.09546
MYO15A myosin XVA 2.08963
DFNB31 deafness, autosomal recessive 31 2.05394
USH1C Usher syndrome 1C (autosomal recessive, severe) 2.01052
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 1.6836
CLRN1 clarin 1 1.54065
ADGRV1 adhesion G protein-coupled receptor V1 1.47457
PTPRQ protein tyrosine phosphatase, receptor type, Q 1.41306
MYO3A myosin IIIA 1.40354
PLS1 plastin 1 1.36307
TRIOBP TRIO and F-actin binding protein 1.32871
USH2A Usher syndrome 2A (autosomal recessive, mild) 1.27133
ATOH1 atonal homolog 1 (Drosophila) 1.24445
MYH15 myosin, heavy chain 15 1.23088
STRCP1 stereocilin pseudogene 1 1.21946
STRC stereocilin 1.21946
FSCN1 fascin actin-bundling protein 1 1.20035
MYO6 myosin VI 1.19931
CFAP52 cilia and flagella associated protein 52 1.1603
MYO1C myosin IC 1.14597
USH1G Usher syndrome 1G (autosomal recessive) 1.13829
POU4F3 POU class 4 homeobox 3 1.13574
MCOLN3 mucolipin 3 1.12296
PTPRR protein tyrosine phosphatase, receptor type, R 1.11837
TMC2 transmembrane channel-like 2 1.11378
TMIE transmembrane inner ear 1.10919
TPRN taperin 1.09442
BARHL1 BarH-like homeobox 1 1.07258
PDZD7 PDZ domain containing 7 1.0665
CLIC5 chloride intracellular channel 5 1.03129
GRXCR2 glutaredoxin, cysteine rich 2 1.00547
GRXCR1 glutaredoxin, cysteine rich 1 0.942584
MYO3B myosin IIIB 0.911113
FSCN2 fascin actin-bundling protein 2, retinal 0.905996
ELMOD3 ELMO/CED-12 domain containing 3 0.899499
ELMOD1 ELMO/CED-12 domain containing 1 0.890707
VEZT vezatin, adherens junctions transmembrane protein 0.884705
VANGL2 VANGL planar cell polarity protein 2 0.872266
MYO1E myosin IE 0.864907
EPS8 epidermal growth factor receptor pathway substrate 8 0.84791
LOXHD1 lipoxygenase homology domains 1 0.847451
TMC1 transmembrane channel-like 1 0.8245
TECTA tectorin alpha 0.811193
CEACAM16 carcinoembryonic antigen-related cell adhesion molecule 16 0.80523
RDX radixin 0.800645
FCHSD1 FCH and double SH3 domains 1 0.797895
ADGRG2 adhesion G protein-coupled receptor G2 0.787359
EZR ezrin 0.768171
ELMOD2 ELMO/CED-12 domain containing 2 0.762252
CES5A carboxylesterase 5A 0.749999
TWF2 twinfilin actin binding protein 2 0.746381
KNCN kinocilin 0.740515
KPTN kaptin (actin binding protein) 0.728389
EPS8L2 EPS8-like 2 0.716791
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.715458
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.715014
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.71457
DVL2 dishevelled segment polarity protein 2 0.712351
DFNB59 deafness, autosomal recessive 59 0.689888
MYH14 myosin, heavy chain 14, non-muscle 0.656895
PRICKLE1 prickle homolog 1 (Drosophila) 0.654741
SPZ1 spermatogenic leucine zipper 1 0.651729
ACTG1 actin gamma 1 0.644429
OTOG otogelin 0.612895
ATP6V1E1 ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1 0.602331
FSCN3 fascin actin-bundling protein 3, testicular 0.599802
TBC1D24 TBC1 domain family, member 24 0.595173
MYO7B myosin VIIB 0.594332
TRPA1 transient receptor potential cation channel, subfamily A, member 1 0.583431
CNGA3 cyclic nucleotide gated channel alpha 3 0.582176
FZD6 frizzled class receptor 6 0.551838
OCM oncomodulin 0.54194
FCHSD2 FCH and double SH3 domains 2 0.541117
MSN moesin 0.535361
EMILIN1 elastin microfibril interfacer 1 0.53413
MKS1 Meckel syndrome, type 1 0.533309
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.533309
TECTB tectorin beta 0.533309
DNAH8 dynein, axonemal, heavy chain 8 0.529618
FAM65B family with sequence similarity 65, member B 0.526341
MYO1H myosin IH 0.525931
OCM2 oncomodulin 2 0.525522
PDE6C phosphodiesterase 6C, cGMP-specific, cone, alpha prime 0.512047
MISP mitotic spindle positioning 0.51164
CNGA4 cyclic nucleotide gated channel alpha 4 0.50757
C4BPA complement component 4 binding protein, alpha 0.50757
ATP2B1 ATPase, Ca++ transporting, plasma membrane 1 0.501881
CIB2 calcium and integrin binding family member 2 0.488519
CPLX3 complexin 3 0.488115
SLC9A3R2 solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 0.478038
AQP9 aquaporin 9 0.477233
LHFPL5 lipoma HMGIC fusion partner-like 5 0.476831
PLS3 plastin 3 0.476027
MIR183 microRNA 183 0.4676
FOXD2 forkhead box D2 0.462798
C4B complement component 4B (Chido blood group) 0.458803
DOCK4 dedicator of cytokinesis 4 0.458006
MCOLN2 mucolipin 2 0.452029
DNAAF1 dynein, axonemal, assembly factor 1 0.434196
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.431041
MSRB3 methionine sulfoxide reductase B3 0.426711
LRRC4C leucine rich repeat containing 4C 0.412601
EPB41 erythrocyte membrane protein band 4.1 0.410649
CALB1 calbindin 1, 28kDa 0.398587
PRICKLE2 prickle homolog 2 (Drosophila) 0.390841
ARL5B ADP-ribosylation factor-like 5B 0.385436
MYO1B myosin IB 0.37697
PARD6B par-6 family cell polarity regulator beta 0.373899
ITGA8 integrin, alpha 8 0.373899
SYBU syntabulin (syntaxin-interacting) 0.369301
CALB2 calbindin 2 0.367388
GFI1 growth factor independent 1 transcription repressor 0.366623
PCDH11Y protocadherin 11 Y-linked 0.363567
MBNL2 muscleblind-like splicing regulator 2 0.357086
PCDH11X protocadherin 11 X-linked 0.355944
LIG3 ligase III, DNA, ATP-dependent 0.355563
SYNJ2 synaptojanin 2 0.352901
IFT80 intraflagellar transport 80 0.336241
ACTB actin, beta 0.334356
MYH9 myosin, heavy chain 9, non-muscle 0.320451
MYO1F myosin IF 0.320077
NOTCH1 notch 1 0.31783
PIGY phosphatidylinositol glycan anchor biosynthesis, class Y 0.311478
EHD4 EH-domain containing 4 0.311478
ZAN zonadhesin (gene/pseudogene) 0.295489
ATP8B1 ATPase, aminophospholipid transporter, class I, type 8B, member 1 0.294378
ACPP acid phosphatase, prostate 0.286983
MPP3 membrane protein, palmitoylated 3 (MAGUK p55 subfamily member 3) 0.281085
COBL cordon-bleu WH2 repeat protein 0.277774
TSPAN8 tetraspanin 8 0.275936
TTC8 tetratricopeptide repeat domain 8 0.256925
ARHGAP17 Rho GTPase activating protein 17 0.252927
SPA17 sperm autoantigenic protein 17 0.250026
ATP8A1 ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1 0.248578
GANAB glucosidase, alpha; neutral AB 0.244962
FZD3 frizzled class receptor 3 0.236324
IRF6 interferon regulatory factor 6 0.235249
TRPM1 transient receptor potential cation channel, subfamily M, member 1 0.230958
FHL1 four and a half LIM domains 1 0.229888
ANK1 ankyrin 1, erythrocytic 0.229532
DOCK2 dedicator of cytokinesis 2 0.224913
DVL3 dishevelled segment polarity protein 3 0.222436
UNC45B unc-45 homolog B (C. elegans) 0.217511
MGAM maltase-glucoamylase 0.213322
SPAG6 sperm associated antigen 6 0.210203
EHD2 EH-domain containing 2 0.200328
TPM1 tropomyosin 1 (alpha) 0.196669
ATP2B3 ATPase, Ca++ transporting, plasma membrane 3 0.195025
NR1D1 nuclear receptor subfamily 1, group D, member 1 0.190814
ASIC2 acid sensing (proton gated) ion channel 2 0.190175
DOCK5 dedicator of cytokinesis 5 0.179459
BTNL2 butyrophilin-like 2 0.178588
SHB Src homology 2 domain containing adaptor protein B 0.176305
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 0.176305
PACSIN1 protein kinase C and casein kinase substrate in neurons 1 0.174911
NEUROG1 neurogenin 1 0.172468
ALPPL2 alkaline phosphatase, placental-like 2 0.17141
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) 0.17141
ALPL alkaline phosphatase, liver/bone/kidney 0.171149
ALPP alkaline phosphatase, placental 0.170888
ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 0.170629
CNGB1 cyclic nucleotide gated channel beta 1 0.170629
OPA1 optic atrophy 1 (autosomal dominant) 0.169859
NOX3 NADPH oxidase 3 0.166643
PTPRD protein tyrosine phosphatase, receptor type, D 0.16342
ARL2 ADP-ribosylation factor-like 2 0.16233
RARG retinoic acid receptor, gamma 0.159268
PTPN12 protein tyrosine phosphatase, non-receptor type 12 0.158315