stereocilia tip link Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description A stereocilia link that is formed by a fine filament running more or less vertically upward from the tip of each shorter stereocilium to attach at a higher point on its adjacent taller neighbor. Tilting the bundle puts tension on the filaments, which pull on mechanically gated ion channels in the membrane of the stereocilia. (Gene Ontology, GO_0002140)
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Genes

9 proteins co-occuring with the stereocilia tip link cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
CDH23 cadherin-related 23 1.99905
CNGA3 cyclic nucleotide gated channel alpha 3 1.19365
EMILIN1 elastin microfibril interfacer 1 1.11378
USH1C Usher syndrome 1C (autosomal recessive, severe) 1.0109
PCDH15 protocadherin-related 15 0.954961
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 0.868586
ATP2B2 ATPase, Ca++ transporting, plasma membrane 2 0.785529
NR0B1 nuclear receptor subfamily 0, group B, member 1 0.748189
MYO7A myosin VIIA 0.739614