staurosporine-312 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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Genes

198 genes differentially expressed following the staurosporine-312 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
ABLIM3 actin binding LIM protein family, member 3
ACACA acetyl-CoA carboxylase alpha
ACOT11 acyl-CoA thioesterase 11
AMELY amelogenin, Y-linked
ANGPT4 angiopoietin 4
AP1S1 adaptor-related protein complex 1, sigma 1 subunit
APP amyloid beta (A4) precursor protein
ARHGAP33 Rho GTPase activating protein 33
ARHGDIB Rho GDP dissociation inhibitor (GDI) beta
ATP6V0A1 ATPase, H+ transporting, lysosomal V0 subunit a1
BCL7C B-cell CLL/lymphoma 7C
BEST2 bestrophin 2
C16ORF59 chromosome 16 open reading frame 59
CA11 carbonic anhydrase XI
CAMK1D calcium/calmodulin-dependent protein kinase ID
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase
CDK10 cyclin-dependent kinase 10
CHD5 chromodomain helicase DNA binding protein 5
CHERP calcium homeostasis endoplasmic reticulum protein
CHRM4 cholinergic receptor, muscarinic 4
CLEC11A C-type lectin domain family 11, member A
CNPY3 canopy FGF signaling regulator 3
CTGF connective tissue growth factor
CYP19A1 cytochrome P450, family 19, subfamily A, polypeptide 1
CYP2D6 cytochrome P450, family 2, subfamily D, polypeptide 6
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4
CYR61 cysteine-rich, angiogenic inducer, 61
DENND3 DENN/MADD domain containing 3
DHPS deoxyhypusine synthase
ERCC2 excision repair cross-complementation group 2
ERO1L ERO1-like (S. cerevisiae)
FBXO31 F-box protein 31
FKBP10 FK506 binding protein 10, 65 kDa
FOLR3 folate receptor 3 (gamma)
FOXH1 forkhead box H1
FTCD formimidoyltransferase cyclodeaminase
GABRP gamma-aminobutyric acid (GABA) A receptor, pi
GAS7 growth arrest-specific 7
GPR3 G protein-coupled receptor 3
GRM8 glutamate receptor, metabotropic 8
GYPC glycophorin C (Gerbich blood group)
H2AFY H2A histone family, member Y
H6PD hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
HCFC1R1 host cell factor C1 regulator 1 (XPO1 dependent)
HHLA3 HERV-H LTR-associating 3
HN1L hematological and neurological expressed 1-like
HTR1B 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
IL11 interleukin 11
IL18RAP interleukin 18 receptor accessory protein
INPP4A inositol polyphosphate-4-phosphatase, type I, 107kDa
ITGB5 integrin, beta 5
KIR2DS1 killer cell immunoglobulin-like receptor, two domains, short cytoplasmic tail, 1
KRT17 keratin 17, type I
LGALS8 lectin, galactoside-binding, soluble, 8
LIAS lipoic acid synthetase
LPPR2 lipid phosphate phosphatase-related protein type 2
MTMR10 myotubularin related protein 10
MTMR2 myotubularin related protein 2
MYL1 myosin, light chain 1, alkali; skeletal, fast
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NR6A1 nuclear receptor subfamily 6, group A, member 1
OAS2 2'-5'-oligoadenylate synthetase 2, 69/71kDa
ODF2 outer dense fiber of sperm tails 2
ORC4 origin recognition complex, subunit 4
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PAX1 paired box 1
PEX7 peroxisomal biogenesis factor 7
PLEK2 pleckstrin 2
PNLIPRP1 pancreatic lipase-related protein 1
POGLUT1 protein O-glucosyltransferase 1
PRSS53 protease, serine, 53
PYGB phosphorylase, glycogen; brain
RAB5C RAB5C, member RAS oncogene family
RASIP1 Ras interacting protein 1
RECQL4 RecQ protein-like 4
RRAS related RAS viral (r-ras) oncogene homolog
RUNDC3A RUN domain containing 3A
S100A6 S100 calcium binding protein A6
SEMA6B sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6B
SIK1 salt-inducible kinase 1
SLC12A4 solute carrier family 12 (potassium/chloride transporter), member 4
SLC13A3 solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3
SLC1A1 solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
SLC30A5 solute carrier family 30 (zinc transporter), member 5
SLCO2B1 solute carrier organic anion transporter family, member 2B1
SPTBN1 spectrin, beta, non-erythrocytic 1
SQSTM1 sequestosome 1
TAF15 TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa
TCEB2 transcription elongation factor B (SIII), polypeptide 2 (18kDa, elongin B)
TIMM44 translocase of inner mitochondrial membrane 44 homolog (yeast)
TMEM161A transmembrane protein 161A
ULK2 unc-51 like autophagy activating kinase 2
URB1 URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
USP48 ubiquitin specific peptidase 48
VARS valyl-tRNA synthetase
WNT7A wingless-type MMTV integration site family, member 7A
YY1 YY1 transcription factor
ZNF528 zinc finger protein 528

decreased expression

Symbol Name
ABT1 activator of basal transcription 1
AEN apoptosis enhancing nuclease
AMD1 adenosylmethionine decarboxylase 1
AMIGO2 adhesion molecule with Ig-like domain 2
ANKRD49 ankyrin repeat domain 49
ARID5B AT rich interactive domain 5B (MRF1-like)
ARL4A ADP-ribosylation factor-like 4A
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
B3GNT2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BCL10 B-cell CLL/lymphoma 10
BTG1 B-cell translocation gene 1, anti-proliferative
C14ORF169 chromosome 14 open reading frame 169
CASP8AP2 caspase 8 associated protein 2
CCNF cyclin F
CCNO cyclin O
CDCA8 cell division cycle associated 8
CDR2 cerebellar degeneration-related protein 2, 62kDa
CDR2L cerebellar degeneration-related protein 2-like
CEBPA CCAAT/enhancer binding protein (C/EBP), alpha
CEBPB CCAAT/enhancer binding protein (C/EBP), beta
CEBPZ CCAAT/enhancer binding protein (C/EBP), zeta
CHD1 chromodomain helicase DNA binding protein 1
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
CKAP2 cytoskeleton associated protein 2
CKS2 CDC28 protein kinase regulatory subunit 2
CLDN4 claudin 4
CLUHP3 clustered mitochondria (cluA/CLU1) homolog pseudogene 3
COIL coilin
CSTF1 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa
DKK1 dickkopf WNT signaling pathway inhibitor 1
DNAJB1 DnaJ (Hsp40) homolog, subfamily B, member 1
E2F6 E2F transcription factor 6
EIF4ENIF1 eukaryotic translation initiation factor 4E nuclear import factor 1
EPHA4 EPH receptor A4
ERCC6L excision repair cross-complementation group 6-like
FADD Fas (TNFRSF6)-associated via death domain
FAM46A family with sequence similarity 46, member A
FANCF Fanconi anemia, complementation group F
FASTKD3 FAST kinase domains 3
FBXL14 F-box and leucine-rich repeat protein 14
FBXO5 F-box protein 5
FOXD1 forkhead box D1
GOLPH3L golgi phosphoprotein 3-like
GRWD1 glutamate-rich WD repeat containing 1
GTF2B general transcription factor IIB
GTF2H2B general transcription factor IIH, polypeptide 2B (pseudogene)
GUSBP3 glucuronidase, beta pseudogene 3
HERPUD1 homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
HJURP Holliday junction recognition protein
ID1 inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
IER5 immediate early response 5
IRF2BP1 interferon regulatory factor 2 binding protein 1
IRS1 insulin receptor substrate 1
KLF4 Kruppel-like factor 4 (gut)
KNOP1 lysine-rich nucleolar protein 1
MCL1 myeloid cell leukemia 1
MED17 mediator complex subunit 17
METTL18 methyltransferase like 18
MGAT1 mannosyl (alpha-1,3-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
MIS12 MIS12 kinetochore complex component
MOAP1 modulator of apoptosis 1
OSR2 odd-skipped related transciption factor 2
PALB2 partner and localizer of BRCA2
PLK2 polo-like kinase 2
PNRC2 proline-rich nuclear receptor coactivator 2
POP1 processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PPP1R8 protein phosphatase 1, regulatory subunit 8
PRPF38B pre-mRNA processing factor 38B
QTRTD1 queuine tRNA-ribosyltransferase domain containing 1
RBM15 RNA binding motif protein 15
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis)
RIOK2 RIO kinase 2
RND3 Rho family GTPase 3
RNF113A ring finger protein 113A
RSBN1 round spermatid basic protein 1
SLC19A2 solute carrier family 19 (thiamine transporter), member 2
SLC30A1 solute carrier family 30 (zinc transporter), member 1
SLC38A2 solute carrier family 38, member 2
SMG8 SMG8 nonsense mediated mRNA decay factor
SUV420H1 suppressor of variegation 4-20 homolog 1 (Drosophila)
TAF5 TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 100kDa
TBCC tubulin folding cofactor C
TGIF1 TGFB-induced factor homeobox 1
TGS1 trimethylguanosine synthase 1
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A
TRIB1 tribbles pseudokinase 1
TRMT12 tRNA methyltransferase 12 homolog (S. cerevisiae)
TSC22D1 TSC22 domain family, member 1
URB2 URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
URGCP upregulator of cell proliferation
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae)
VANGL1 VANGL planar cell polarity protein 1
ZBED5 zinc finger, BED-type containing 5
ZBTB24 zinc finger and BTB domain containing 24
ZC3H4 zinc finger CCCH-type containing 4
ZNF146 zinc finger protein 146
ZNF217 zinc finger protein 217
ZNF443 zinc finger protein 443
ZNF7 zinc finger protein 7