squamous cell carcinoma Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A carcinoma that derives_from squamous epithelial cells. (Human Disease Ontology, DOID_1749)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:1749
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Genes

93 genes associated with the disease squamous cell carcinoma in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
FUT6 fucosyltransferase 6 (alpha (1,3) fucosyltransferase) 3.99483
FUT2 fucosyltransferase 2 (secretor status included) 3.51446
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase) 3.08092
FUT3 fucosyltransferase 3 (galactoside 3(4)-L-fucosyltransferase, Lewis blood group) 2.40544
FAM3B family with sequence similarity 3, member B 2.07237
RASIP1 Ras interacting protein 1 1.99432
AFP alpha-fetoprotein 1.93944
PPIP5K1 diphosphoinositol pentakisphosphate kinase 1 1.78856
DBP D site of albumin promoter (albumin D-box) binding protein 1.76717
SEC1P secretory blood group 1, pseudogene 1.76045
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 1.69848
RPL18 ribosomal protein L18 1.65109
SULT2B1 sulfotransferase family, cytosolic, 2B, member 1 1.64472
B3GNT3 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3 1.58623
MAP1A microtubule-associated protein 1A 1.35898
CA11 carbonic anhydrase XI 1.35121
CHST11 carbohydrate (chondroitin 4) sulfotransferase 11 1.34633
TP53BP1 tumor protein p53 binding protein 1 1.33817
SND1 staphylococcal nuclease and tudor domain containing 1 0.96005
GRIK2 glutamate receptor, ionotropic, kainate 2 0.921998
PIP5K1B phosphatidylinositol-4-phosphate 5-kinase, type I, beta 0.915976
FBXO33 F-box protein 33 0.82192
PPP4R1L protein phosphatase 4, regulatory subunit 1-like (pseudogene) 0.821519
ETV6 ets variant 6 0.814557
PTPRJ protein tyrosine phosphatase, receptor type, J 0.807358
ANKRD17 ankyrin repeat domain 17 0.787916
NFIB nuclear factor I/B 0.78104
VWF von Willebrand factor 0.775167
USP34 ubiquitin specific peptidase 34 0.766993
ACOXL acyl-CoA oxidase-like 0.755798
SLC17A8 solute carrier family 17 (vesicular glutamate transporter), member 8 0.727991
DFNA5 deafness, autosomal dominant 5 0.722673
LNX1 ligand of numb-protein X 1, E3 ubiquitin protein ligase 0.687994
PPIH peptidylprolyl isomerase H (cyclophilin H) 0.676035
TRAM2 translocation associated membrane protein 2 0.675898
ZNF395 zinc finger protein 395 0.668836
JAG1 jagged 1 0.656693
CCDC3 coiled-coil domain containing 3 0.654134
KDM1A lysine (K)-specific demethylase 1A 0.637975
DCC DCC netrin 1 receptor 0.630986
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 0.627273
WWOX WW domain containing oxidoreductase 0.624172
MGAT5B mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase, isozyme B 0.618776
SIM1 single-minded family bHLH transcription factor 1 0.618776
NELL1 NEL-like 1 (chicken) 0.614068
NFATC2 nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 0.613378
SYK spleen tyrosine kinase 0.59964
FHIT fragile histidine triad 0.59964
SASH1 SAM and SH3 domain containing 1 0.59738
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.596808
CNTNAP2 contactin associated protein-like 2 0.592677
PREX2 phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 0.588302
GALNT5 polypeptide N-acetylgalactosaminyltransferase 5 0.586586
MMP2 matrix metallopeptidase 2 0.577495
SOX5 SRY (sex determining region Y)-box 5 0.571834
OPCML opioid binding protein/cell adhesion molecule-like 0.570187
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.568383
SAMD4A sterile alpha motif domain containing 4A 0.560163
TAF3 TAF3 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 140kDa 0.560163
AQR aquarius intron-binding spliceosomal factor 0.559788
GALNT13 polypeptide N-acetylgalactosaminyltransferase 13 0.559788
ATRNL1 attractin-like 1 0.559788
FGF14 fibroblast growth factor 14 0.559601
CNTN4 contactin 4 0.545546
ZBTB46 zinc finger and BTB domain containing 46 0.544628
POLE polymerase (DNA directed), epsilon, catalytic subunit 0.543994
STRN4 striatin, calmodulin binding protein 4 0.542744
TPTE2 transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 0.541061
EIF3L eukaryotic translation initiation factor 3, subunit L 0.531884
ITSN1 intersectin 1 (SH3 domain protein) 0.529803
HS6ST3 heparan sulfate 6-O-sulfotransferase 3 0.52866
UBE2E2 ubiquitin-conjugating enzyme E2E 2 0.527537
SLC36A4 solute carrier family 36 (proton/amino acid symporter), member 4 0.526798
IRAK3 interleukin-1 receptor-associated kinase 3 0.525584
USP47 ubiquitin specific peptidase 47 0.52333
BCR breakpoint cluster region 0.52115
LOC643406 uncharacterized LOC643406 0.520142
SORCS3 sortilin-related VPS10 domain containing receptor 3 0.516888
PCSK5 proprotein convertase subtilisin/kexin type 5 0.516256
COL25A1 collagen, type XXV, alpha 1 0.51239
RASGRP3 RAS guanyl releasing protein 3 (calcium and DAG-regulated) 0.512193
GRIK4 glutamate receptor, ionotropic, kainate 4 0.509209
GPC5 glypican 5 0.508647
ASIC2 acid sensing (proton gated) ion channel 2 0.507394
CAMK4 calcium/calmodulin-dependent protein kinase IV 0.506889
PTPRG protein tyrosine phosphatase, receptor type, G 0.505613
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 0.503687
CRYL1 crystallin, lambda 1 0.502091
FTO fat mass and obesity associated 0.501894
NPAS3 neuronal PAS domain protein 3 0.500861
RPTOR regulatory associated protein of MTOR, complex 1 0.500478
DOCK1 dedicator of cytokinesis 1 0.498059
TSPEAR thrombospondin-type laminin G domain and EAR repeats 0.497336