sporadic breast cancer Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
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Genes

147 genes co-occuring with the disease sporadic breast cancer in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
BRCA1 breast cancer 1, early onset 2.54238
BRCA2 breast cancer 2, early onset 2.13617
ESR1 estrogen receptor 1 1.46583
PGR progesterone receptor 1.46276
C11ORF30 chromosome 11 open reading frame 30 1.37469
TP53 tumor protein p53 1.34112
ATM ATM serine/threonine kinase 1.29527
CHEK2 checkpoint kinase 2 1.25907
RAD51 RAD51 recombinase 1.24385
ERBB2 erb-b2 receptor tyrosine kinase 2 1.21089
BARD1 BRCA1 associated RING domain 1 1.09923
NBR2 neighbor of BRCA1 gene 2 (non-protein coding) 1.08076
ARL17B ADP-ribosylation factor-like 17B 1.0585
CELF3 CUGBP, Elav-like family member 3 0.976744
XRCC2 X-ray repair complementing defective repair in Chinese hamster cells 2 0.909376
RHOBTB2 Rho-related BTB domain containing 2 0.881472
PTEN phosphatase and tensin homolog 0.858952
PALB2 partner and localizer of BRCA2 0.857315
FHIT fragile histidine triad 0.848307
TTC4 tetratricopeptide repeat domain 4 0.847898
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 0.828229
SEPHS2 selenophosphate synthetase 2 0.817976
CDH7 cadherin 7, type 2 0.78066
ESR2 estrogen receptor 2 (ER beta) 0.770027
GSTM1 glutathione S-transferase mu 1 0.768393
FANCD2 Fanconi anemia, complementation group D2 0.751271
EXOSC8 exosome component 8 0.747204
GSTTP1 glutathione S-transferase theta pseudogene 1 0.724907
GSTT1 glutathione S-transferase theta 1 0.724502
MNT MAX network transcriptional repressor 0.717635
CDK10 cyclin-dependent kinase 10 0.678701
MIER1 mesoderm induction early response 1, transcriptional regulator 0.66755
XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 0.66596
GABRP gamma-aminobutyric acid (GABA) A receptor, pi 0.652484
CDH15 cadherin 15, type 1, M-cadherin (myotubule) 0.644981
HUS1 HUS1 checkpoint homolog (S. pombe) 0.635921
DIXDC1 DIX domain containing 1 0.627672
EGFR epidermal growth factor receptor 0.620617
FNDC3A fibronectin type III domain containing 3A 0.609666
CDH19 cadherin 19, type 2 0.597961
HSD17B2 hydroxysteroid (17-beta) dehydrogenase 2 0.597571
APEX1 APEX nuclease (multifunctional DNA repair enzyme) 1 0.597181
ZNF703 zinc finger protein 703 0.582384
SFN stratifin 0.573439
ERLIN2 ER lipid raft associated 2 0.56722
CDKN2A cyclin-dependent kinase inhibitor 2A 0.5645
SIPA1 signal-induced proliferation-associated 1 0.557897
IGHG2 immunoglobulin heavy constant gamma 2 (G2m marker) 0.54393
HIC1 hypermethylated in cancer 1 0.526132
RAD54B RAD54 homolog B (S. cerevisiae) 0.520346
STK11 serine/threonine kinase 11 0.511496
CCND1 cyclin D1 0.511496
PHRF1 PHD and ring finger domains 1 0.503824
PARP1 poly (ADP-ribose) polymerase 1 0.498085
FGFR2 fibroblast growth factor receptor 2 0.486646
USP1 ubiquitin specific peptidase 1 0.485885
ID4 inhibitor of DNA binding 4, dominant negative helix-loop-helix protein 0.467684
CDK17 cyclin-dependent kinase 17 0.463905
MAGED2 melanoma antigen family D2 0.460129
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.456355
MIR148B microRNA 148b 0.456355
RB1 retinoblastoma 1 0.454847
ZNF365 zinc finger protein 365 0.448064
NOL9 nucleolar protein 9 0.444676
CYP1A1 cytochrome P450, family 1, subfamily A, polypeptide 1 0.440914
KDM5B lysine (K)-specific demethylase 5B 0.43941
PROX1 prospero homeobox 1 0.428891
H2AFX H2A histone family, member X 0.42814
FANCL Fanconi anemia, complementation group L 0.42364
CTCF CCCTC-binding factor (zinc finger protein) 0.415024
TFDP1 transcription factor Dp-1 0.40904
NTHL1 nth endonuclease III-like 1 (E. coli) 0.40904
SMARCE1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1 0.400453
GSTZ1 glutathione S-transferase zeta 1 0.40008
DLX4 distal-less homeobox 4 0.399707
BRIP1 BRCA1 interacting protein C-terminal helicase 1 0.398589
ERCC2 excision repair cross-complementation group 2 0.397471
GSTP1 glutathione S-transferase pi 1 0.390025
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 0.387051
MTUS1 microtubule associated tumor suppressor 1 0.378143
CCAR2 cell cycle and apoptosis regulator 2 0.371477
PHB prohibitin 0.368888
HSD17B1P1 hydroxysteroid (17-beta) dehydrogenase 1 pseudogene 1 0.366301
AURKA aurora kinase A 0.362239
ZNF410 zinc finger protein 410 0.353763
PRKDC protein kinase, DNA-activated, catalytic polypeptide 0.351187
RARB retinoic acid receptor, beta 0.349717
HPGDS hematopoietic prostaglandin D synthase 0.347511
IGLV9-49 immunoglobulin lambda variable 9-49 0.342006
MEMO1 mediator of cell motility 1 0.340906
GGCT gamma-glutamylcyclotransferase 0.338707
ZBTB7A zinc finger and BTB domain containing 7A 0.335412
DVL3 dishevelled segment polarity protein 3 0.332121
POU4F2 POU class 4 homeobox 2 0.323365
POLD1 polymerase (DNA directed), delta 1, catalytic subunit 0.318635
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.316456
CDT1 chromatin licensing and DNA replication factor 1 0.307757
GPR148 G protein-coupled receptor 148 0.291539
DLAT dihydrolipoamide S-acetyltransferase 0.290462
GUK1 guanylate kinase 1 0.28831
GSTA3 glutathione S-transferase alpha 3 0.287235
GSTA2 glutathione S-transferase alpha 2 0.28616
GSTA4 glutathione S-transferase alpha 4 0.285086
CUL4A cullin 4A 0.283297
UHRF1 ubiquitin-like with PHD and ring finger domains 1 0.28151
GSTA1 glutathione S-transferase alpha 1 0.279367
CYP1B1 cytochrome P450, family 1, subfamily B, polypeptide 1 0.277584
BTLA B and T lymphocyte associated 0.272597
DVL2 dishevelled segment polarity protein 2 0.267267
CD276 CD276 molecule 0.263368
CDH17 cadherin 17, LI cadherin (liver-intestine) 0.257005
C1QBP complement component 1, q subcomponent binding protein 0.255946
DAPK1 death-associated protein kinase 1 0.254183
KRT5 keratin 5, type II 0.253831
PRKCZ protein kinase C, zeta 0.253479
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.249608
CKAP5 cytoskeleton associated protein 5 0.246799
ING1 inhibitor of growth family, member 1 0.246098
FANCA Fanconi anemia, complementation group A 0.240847
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 0.239101
GMNN geminin, DNA replication inhibitor 0.233878
TLX3 T-cell leukemia homeobox 3 0.227988
EN2 engrailed homeobox 2 0.221793
MAP3K1 mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase 0.218374
CLCA2 chloride channel accessory 2 0.208245
CCND2 cyclin D2 0.203604
RAD51C RAD51 paralog C 0.200331
CGB7 chorionic gonadotropin, beta polypeptide 7 0.198064
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha 0.197742
TJP2 tight junction protein 2 0.19742
CGB5 chorionic gonadotropin, beta polypeptide 5 0.197099
POU4F1 POU class 4 homeobox 1 0.194548
DNMT3B DNA (cytosine-5-)-methyltransferase 3 beta 0.190476
MSH2 mutS homolog 2 0.188938
KLK10 kallikrein-related peptidase 10 0.18621
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.18472
CHMP1A charged multivesicular body protein 1A 0.17896
CGB chorionic gonadotropin, beta polypeptide 0.177851
CGB8 chorionic gonadotropin, beta polypeptide 8 0.177301
EFEMP1 EGF containing fibulin-like extracellular matrix protein 1 0.171036
COMT catechol-O-methyltransferase 0.169812
TOB1 transducer of ERBB2, 1 0.166768
RAD52 RAD52 homolog (S. cerevisiae) 0.165874
BAD BCL2-associated agonist of cell death 0.164149
CDK4 cyclin-dependent kinase 4 0.162908
FANCI Fanconi anemia, complementation group I 0.161331
TPX2 TPX2, microtubule-associated 0.158605