spleen hypoplasia Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0000694
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Genes

104 gene mutations causing the spleen hypoplasia phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
AHR aryl hydrocarbon receptor
AKAP13 A kinase (PRKA) anchor protein 13
AMER1 APC membrane recruitment protein 1
ARHGAP1 Rho GTPase activating protein 1
ARID5B AT rich interactive domain 5B (MRF1-like)
ARMC4 armadillo repeat containing 4
ASB1 ankyrin repeat and SOCS box containing 1
BACH2 BTB and CNC homology 1, basic leucine zipper transcription factor 2
BAG3 BCL2-associated athanogene 3
BAG4 BCL2-associated athanogene 4
BCL6 B-cell CLL/lymphoma 6
BLNK B-cell linker
BRCA2 breast cancer 2, early onset
BTK Bruton agammaglobulinemia tyrosine kinase
C1ORF127 chromosome 1 open reading frame 127
CACYBP calcyclin binding protein
CCDC151 coiled-coil domain containing 151
CCDC39 coiled-coil domain containing 39
CD3G CD3g molecule, gamma (CD3-TCR complex)
CDK6 cyclin-dependent kinase 6
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1)
CEP290 centrosomal protein 290kDa
CFC1 cripto, FRL-1, cryptic family 1
COL10A1 collagen, type X, alpha 1
CYS1 cystin 1
DAW1 dynein assembly factor with WDR repeat domains 1
DCLRE1C DNA cross-link repair 1C
DNAH11 dynein, axonemal, heavy chain 11
DNAI1 dynein, axonemal, intermediate chain 1
DOCK2 dedicator of cytokinesis 2
ELAVL1 ELAV like RNA binding protein 1
ERCC1 excision repair cross-complementation group 1
ESR2 estrogen receptor 2 (ER beta)
EWSR1 EWS RNA-binding protein 1
FGF23 fibroblast growth factor 23
FGF7 fibroblast growth factor 7
FIG4 FIG4 phosphoinositide 5-phosphatase
FLT3LG fms-related tyrosine kinase 3 ligand
FOXN1 forkhead box N1
GIMAP1-GIMAP5 GIMAP1-GIMAP5 readthrough
GON4L gon-4-like (C. elegans)
HAX1 HCLS1 associated protein X-1
HOXA9 homeobox A9
HOXB4 homeobox B4
IFNGR1 interferon gamma receptor 1
IGF2BP1 insulin-like growth factor 2 mRNA binding protein 1
IGKC immunoglobulin kappa constant
IGLL1 immunoglobulin lambda-like polypeptide 1
IL2RG interleukin 2 receptor, gamma
IL31RA interleukin 31 receptor A
IL7 interleukin 7
IL7R interleukin 7 receptor
INVS inversin
JAK3 Janus kinase 3
JARID2 jumonji, AT rich interactive domain 2
KAT6A K(lysine) acetyltransferase 6A
KIAA0101 KIAA0101
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
KLHL6 kelch-like family member 6
KLRK1 killer cell lectin-like receptor subfamily K, member 1
KMT2E lysine (K)-specific methyltransferase 2E
LBR lamin B receptor
LYN LYN proto-oncogene, Src family tyrosine kinase
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase
MSI2 musashi RNA-binding protein 2
MYBL1 v-myb avian myeloblastosis viral oncogene homolog-like 1
MYC v-myc avian myelocytomatosis viral oncogene homolog
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NHEJ1 nonhomologous end-joining factor 1
NKX2-5 NK2 homeobox 5
NLK nemo-like kinase
NODAL nodal growth differentiation factor
PFDN1 prefoldin subunit 1
PIK3AP1 phosphoinositide-3-kinase adaptor protein 1
PIK3CD phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit delta
PIKFYVE phosphoinositide kinase, FYVE finger containing
PITX2 paired-like homeodomain 2
POU2AF1 POU class 2 associating factor 1
PRKDC protein kinase, DNA-activated, catalytic polypeptide
RAG1 recombination activating gene 1
RAG2 recombination activating gene 2
RASSF2 Ras association (RalGDS/AF-6) domain family member 2
RASSF5 Ras association (RalGDS/AF-6) domain family member 5
RHOH ras homolog family member H
RRAS2 related RAS viral (r-ras) oncogene homolog 2
SERPINI2 serpin peptidase inhibitor, clade I (pancpin), member 2
SGPL1 sphingosine-1-phosphate lyase 1
SIAE sialic acid acetylesterase
SIRT6 sirtuin 6
SMAD3 SMAD family member 3
SP4 Sp4 transcription factor
TBC1D32 TBC1 domain family, member 32
TK1 thymidine kinase 1, soluble
TNFSF13B tumor necrosis factor (ligand) superfamily, member 13b
TP53 tumor protein p53
TRAF3 TNF receptor-associated factor 3
TRAT1 T cell receptor associated transmembrane adaptor 1
XRCC5 X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6
ZFPM1 zinc finger protein, FOG family member 1
ZIC3 Zic family member 3