spleen atrophy Gene Set

Dataset MPO Gene-Phenotype Associations
Category disease or phenotype associations
Type phenotype
Description acquired diminution of the size of the spleen associated with wasting as from death and reabsorbtion of cells, diminished cellular proliferation, decreased cellular volume, pressure, ischemia, malnutrition, reduced function or malfunction, or hormonal changes (Mammalian Phenotype Ontology, MP_0003643)
External Link http://www.informatics.jax.org/searches/Phat.cgi?id=MP:0003643
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Genes

19 gene mutations causing the spleen atrophy phenotype in transgenic mice from the MPO Gene-Phenotype Associations dataset.

Symbol Name
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase
ASXL1 additional sex combs like transcriptional regulator 1
BCL2 B-cell CLL/lymphoma 2
CD2AP CD2-associated protein
HTRA2 HtrA serine peptidase 2
NFKB2 nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
NKX2-3 NK2 homeobox 3
PARL presenilin associated, rhomboid-like
PSIP1 PC4 and SFRS1 interacting protein 1
RORA RAR-related orphan receptor A
RRM2B ribonucleotide reductase M2 B (TP53 inducible)
SCG5 secretogranin V
STK36 serine/threonine kinase 36
TCF3 transcription factor 3
TDP2 tyrosyl-DNA phosphodiesterase 2
TERT telomerase reverse transcriptase
TRAF2 TNF receptor-associated factor 2
WWOX WW domain containing oxidoreductase