spiramycin-3844 Gene Set

Dataset CMAP Signatures of Differentially Expressed Genes for Small Molecules
Category transcriptomics
Type small molecule perturbation
Description small molecule perturbation identified as [small molecule name]-[perturbation ID] (ChIP-X Enrichment Analysis)
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194 genes differentially expressed following the spiramycin-3844 small molecule perturbation from the CMAP Signatures of Differentially Expressed Genes for Small Molecules dataset.

increased expression

Symbol Name
A4GALT alpha 1,4-galactosyltransferase
ABCA7 ATP-binding cassette, sub-family A (ABC1), member 7
ABCB9 ATP-binding cassette, sub-family B (MDR/TAP), member 9
ABO ABO blood group (transferase A, alpha 1-3-N-acetylgalactosaminyltransferase; transferase B, alpha 1-3-galactosyltransferase)
ACVR1B activin A receptor, type IB
AHNAK AHNAK nucleoprotein
AKAP5 A kinase (PRKA) anchor protein 5
ALK anaplastic lymphoma receptor tyrosine kinase
AQP3 aquaporin 3 (Gill blood group)
ARC activity-regulated cytoskeleton-associated protein
ARNT aryl hydrocarbon receptor nuclear translocator
ATF5 activating transcription factor 5
ATN1 atrophin 1
C1QL1 complement component 1, q subcomponent-like 1
C8ORF4 chromosome 8 open reading frame 4
CCDC7 coiled-coil domain containing 7
CD74 CD74 molecule, major histocompatibility complex, class II invariant chain
CD79B CD79b molecule, immunoglobulin-associated beta
COL8A1 collagen, type VIII, alpha 1
CTSO cathepsin O
CUZD1 CUB and zona pellucida-like domains 1
CXCR4 chemokine (C-X-C motif) receptor 4
DAPK3 death-associated protein kinase 3
DIO2 deiodinase, iodothyronine, type II
DLK2 delta-like 2 homolog (Drosophila)
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1
ECE1 endothelin converting enzyme 1
EDA ectodysplasin A
EMC3 ER membrane protein complex subunit 3
ESR1 estrogen receptor 1
EZR ezrin
FBXL7 F-box and leucine-rich repeat protein 7
FCGR2C Fc fragment of IgG, low affinity IIc, receptor for (CD32) (gene/pseudogene)
GAS2L1 growth arrest-specific 2 like 1
GLYR1 glyoxylate reductase 1 homolog (Arabidopsis)
GPER1 G protein-coupled estrogen receptor 1
GPR15 G protein-coupled receptor 15
GSN gelsolin
HECW1 HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
HIST1H4A histone cluster 1, H4a
HLF hepatic leukemia factor
ICOSLG inducible T-cell co-stimulator ligand
IL36RN interleukin 36 receptor antagonist
ING4 inhibitor of growth family, member 4
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2
JAM3 junctional adhesion molecule 3
KIAA0391 KIAA0391
KIAA1109 KIAA1109
KLHL25 kelch-like family member 25
KMT2A lysine (K)-specific methyltransferase 2A
LAMP1 lysosomal-associated membrane protein 1
LMAN1 lectin, mannose-binding, 1
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
MADCAM1 mucosal vascular addressin cell adhesion molecule 1
MAP3K13 mitogen-activated protein kinase kinase kinase 13
MAPK11 mitogen-activated protein kinase 11
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MATN1 matrilin 1, cartilage matrix protein
MED16 mediator complex subunit 16
MORN1 MORN repeat containing 1
MZF1 myeloid zinc finger 1
NMT2 N-myristoyltransferase 2
NR2E3 nuclear receptor subfamily 2, group E, member 3
PAPPA pregnancy-associated plasma protein A, pappalysin 1
PDE4C phosphodiesterase 4C, cAMP-specific
POM121 POM121 transmembrane nucleoporin
PRND prion protein 2 (dublet)
PRTN3 proteinase 3
PSD4 pleckstrin and Sec7 domain containing 4
PVR poliovirus receptor
PXDC1 PX domain containing 1
RBM34 RNA binding motif protein 34
RRN3P1 RNA polymerase I transcription factor homolog (S. cerevisiae) pseudogene 1
RUNX1 runt-related transcription factor 1
SDS serine dehydratase
SEMA7A semaphorin 7A, GPI membrane anchor (John Milton Hagen blood group)
SLC15A1 solute carrier family 15 (oligopeptide transporter), member 1
SLC16A3 solute carrier family 16 (monocarboxylate transporter), member 3
SLC16A4 solute carrier family 16, member 4
SLC23A2 solute carrier family 23 (ascorbic acid transporter), member 2
SLC24A2 solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
SLC3A1 solute carrier family 3 (amino acid transporter heavy chain), member 1
SMARCA4 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
SP1 Sp1 transcription factor
SRCAP Snf2-related CREBBP activator protein
STAC SH3 and cysteine rich domain
STXBP5L syntaxin binding protein 5-like
SYT5 synaptotagmin V
TBC1D22B TBC1 domain family, member 22B
THBS1 thrombospondin 1
TMEM63A transmembrane protein 63A
TMLHE trimethyllysine hydroxylase, epsilon
TMPRSS15 transmembrane protease, serine 15
TP53I11 tumor protein p53 inducible protein 11
UBE2I ubiquitin-conjugating enzyme E2I
VEGFA vascular endothelial growth factor A
WT1-AS WT1 antisense RNA
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase

decreased expression

Symbol Name
A1CF APOBEC1 complementation factor
ACADS acyl-CoA dehydrogenase, C-2 to C-3 short chain
AFAP1 actin filament associated protein 1
AMH anti-Mullerian hormone
ANKH ANKH inorganic pyrophosphate transport regulator
BAK1 BCL2-antagonist/killer 1
BCOR BCL6 corepressor
BFSP1 beaded filament structural protein 1, filensin
BHLHB9 basic helix-loop-helix domain containing, class B, 9
C11ORF80 chromosome 11 open reading frame 80
C14ORF79 chromosome 14 open reading frame 79
C1QTNF3 C1q and tumor necrosis factor related protein 3
C22ORF46 chromosome 22 open reading frame 46
C4BPA complement component 4 binding protein, alpha
CAMK1 calcium/calmodulin-dependent protein kinase I
CEP170B centrosomal protein 170B
CES3 carboxylesterase 3
CHST7 carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
CLDN15 claudin 15
CORO2A coronin, actin binding protein, 2A
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa
CUL9 cullin 9
CWC25 CWC25 spliceosome-associated protein homolog (S. cerevisiae)
DYM dymeclin
DZANK1 double zinc ribbon and ankyrin repeat domains 1
ENOX1 ecto-NOX disulfide-thiol exchanger 1
EPHB6 EPH receptor B6
ERCC5 excision repair cross-complementation group 5
ERN2 endoplasmic reticulum to nucleus signaling 2
FBXW4P1 F-box and WD repeat domain containing 4 pseudogene 1
FLT4 fms-related tyrosine kinase 4
FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group)
GALT galactose-1-phosphate uridylyltransferase
GEMIN8 gem (nuclear organelle) associated protein 8
GPNMB glycoprotein (transmembrane) nmb
HIST1H1B histone cluster 1, H1b
HIST1H4C histone cluster 1, H4c
HIST2H2AA3 histone cluster 2, H2aa3
IGSF1 immunoglobulin superfamily, member 1
IL17RA interleukin 17 receptor A
IL1RAPL2 interleukin 1 receptor accessory protein-like 2
IQSEC2 IQ motif and Sec7 domain 2
LAMP3 lysosomal-associated membrane protein 3
LHX1 LIM homeobox 1
LIME1 Lck interacting transmembrane adaptor 1
LRFN3 leucine rich repeat and fibronectin type III domain containing 3
MANBA mannosidase, beta A, lysosomal
MBNL3 muscleblind-like splicing regulator 3
MYO1F myosin IF
NFKBIL1 nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1
NRGN neurogranin (protein kinase C substrate, RC3)
NSUN6 NOP2/Sun domain family, member 6
NXPE3 neurexophilin and PC-esterase domain family, member 3
NXPH4 neurexophilin 4
OTUB2 OTU deubiquitinase, ubiquitin aldehyde binding 2
PADI3 peptidyl arginine deiminase, type III
PCDHGA8 protocadherin gamma subfamily A, 8
PLEKHS1 pleckstrin homology domain containing, family S member 1
PPP2R5B protein phosphatase 2, regulatory subunit B', beta
PPP3R1 protein phosphatase 3, regulatory subunit B, alpha
PTDSS2 phosphatidylserine synthase 2
PTPRS protein tyrosine phosphatase, receptor type, S
RAB3A RAB3A, member RAS oncogene family
RIN1 Ras and Rab interactor 1
RPL10L ribosomal protein L10-like
S100A9 S100 calcium binding protein A9
SCML2 sex comb on midleg-like 2 (Drosophila)
SHARPIN SHANK-associated RH domain interactor
SKI SKI proto-oncogene
SMARCD3 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
SPATA2L spermatogenesis associated 2-like
SPON2 spondin 2, extracellular matrix protein
STARD5 StAR-related lipid transfer (START) domain containing 5
SUN2 Sad1 and UNC84 domain containing 2
TAOK1 TAO kinase 1
TBC1D2 TBC1 domain family, member 2
TBL1Y transducin (beta)-like 1, Y-linked
TCHH trichohyalin
TCP10 t-complex 10
TGFBR3 transforming growth factor, beta receptor III
TLR2 toll-like receptor 2
TNFRSF13B tumor necrosis factor receptor superfamily, member 13B
TRAIP TRAF interacting protein
TRDMT1 tRNA aspartic acid methyltransferase 1
TRIM5 tripartite motif containing 5
TUBA3C tubulin, alpha 3c
TUBG2 tubulin, gamma 2
USB1 U6 snRNA biogenesis 1
VASH1 vasohibin 1
YARS2 tyrosyl-tRNA synthetase 2, mitochondrial
ZBTB48 zinc finger and BTB domain containing 48
ZNF10 zinc finger protein 10
ZNF358 zinc finger protein 358
ZNF365 zinc finger protein 365
ZNF408 zinc finger protein 408
ZNF639 zinc finger protein 639