spindle Gene Set

Dataset Phosphosite Textmining Biological Term Annotations
Category structural or functional annotations
Type biological term
Description The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. (Gene Ontology, GO_0005819)
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Genes

152 proteins co-occuring with the biological term spindle in abstracts of publications describing phosphosites from the Phosphosite Textmining Biological Term Annotations dataset.

Symbol Name
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA2 annexin A2
APC adenomatous polyposis coli
ATF2 activating transcription factor 2
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
AURKC aurora kinase C
AXIN1 axin 1
BIRC5 baculoviral IAP repeat containing 5
BLM Bloom syndrome, RecQ helicase-like
BORA bora, aurora kinase A activator
BRAF B-Raf proto-oncogene, serine/threonine kinase
BUB1 BUB1 mitotic checkpoint serine/threonine kinase
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B
BUB3 BUB3 mitotic checkpoint protein
CC2D1A coiled-coil and C2 domain containing 1A
CCNB1 cyclin B1
CDC20 cell division cycle 20
CDC25B cell division cycle 25B
CDC25C cell division cycle 25C
CDC6 cell division cycle 6
CDCA2 cell division cycle associated 2
CDCA5 cell division cycle associated 5
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CDK11B cyclin-dependent kinase 11B
CDK2 cyclin-dependent kinase 2
CENPA centromere protein A
CENPT centromere protein T
CENPU centromere protein U
CEP250 centrosomal protein 250kDa
CETN2 centrin, EF-hand protein, 2
CFL1 cofilin 1 (non-muscle)
CHEK1 checkpoint kinase 1
CHEK2 checkpoint kinase 2
CKAP2 cytoskeleton associated protein 2
CLASP2 cytoplasmic linker associated protein 2
CNTROB centrobin, centrosomal BRCA2 interacting protein
CUEDC2 CUE domain containing 2
DAB2 Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila)
DCTN1 dynactin 1
DCTN6 dynactin 6
DIAPH2 diaphanous-related formin 2
DLG1 discs, large homolog 1 (Drosophila)
DNM2 dynamin 2
DSN1 DSN1, MIS12 kinetochore complex component
DVL2 dishevelled segment polarity protein 2
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1
DYNLL1 dynein, light chain, LC8-type 1
ECT2 epithelial cell transforming 2
ELK1 ELK1, member of ETS oncogene family
EPB41 erythrocyte membrane protein band 4.1
ERCC6L excision repair cross-complementation group 6-like
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae)
FADD Fas (TNFRSF6)-associated via death domain
FOXM1 forkhead box M1
GPSM2 G-protein signaling modulator 2
H2AFX H2A histone family, member X
H3F3A H3 histone, family 3A
H3F3B H3 histone, family 3B (H3.3B)
HAUS8 HAUS augmin-like complex, subunit 8
HDAC5 histone deacetylase 5
HIST1H2AI histone cluster 1, H2ai
HIST1H3A histone cluster 1, H3a
HSF1 heat shock transcription factor 1
HTT huntingtin
INCENP inner centromere protein antigens 135/155kDa
JUN jun proto-oncogene
KIF11 kinesin family member 11
KIF22 kinesin family member 22
KIF23 kinesin family member 23
KIF2C kinesin family member 2C
KIZ kizuna centrosomal protein
LATS1 large tumor suppressor kinase 1
LATS2 large tumor suppressor kinase 2
LDLRAP1 low density lipoprotein receptor adaptor protein 1
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAP2K6 mitogen-activated protein kinase kinase 6
MAP9 microtubule-associated protein 9
MAPK1 mitogen-activated protein kinase 1
MAPK14 mitogen-activated protein kinase 14
MAPK3 mitogen-activated protein kinase 3
MAPK8 mitogen-activated protein kinase 8
MAPK9 mitogen-activated protein kinase 9
MAPRE3 microtubule-associated protein, RP/EB family, member 3
MAPT microtubule-associated protein tau
MCM2 minichromosome maintenance complex component 2
MOS v-mos Moloney murine sarcoma viral oncogene homolog
MTOR mechanistic target of rapamycin (serine/threonine kinase)
MYBBP1A MYB binding protein (P160) 1a
MYL12B myosin, light chain 12B, regulatory
NDC80 NDC80 kinetochore complex component
NDE1 nudE neurodevelopment protein 1
NDEL1 nudE neurodevelopment protein 1-like 1
NEDD1 neural precursor cell expressed, developmentally down-regulated 1
NEK2 NIMA-related kinase 2
NEK6 NIMA-related kinase 6
NEK9 NIMA-related kinase 9
NINL ninein-like
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin)
NUMA1 nuclear mitotic apparatus protein 1
NUSAP1 nucleolar and spindle associated protein 1
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1
PBK PDZ binding kinase
PCNT pericentrin
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6
PLK1 polo-like kinase 1
PLK4 polo-like kinase 4
PPP1CA protein phosphatase 1, catalytic subunit, alpha isozyme
PPP1R12A protein phosphatase 1, regulatory subunit 12A
PRC1 protein regulator of cytokinesis 1
PRKAA1 protein kinase, AMP-activated, alpha 1 catalytic subunit
PRKD1 protein kinase D1
PRKD3 protein kinase D3
PRKDC protein kinase, DNA-activated, catalytic polypeptide
PSRC1 proline/serine-rich coiled-coil 1
PTK2 protein tyrosine kinase 2
RACGAP1 Rac GTPase activating protein 1
RAF1 Raf-1 proto-oncogene, serine/threonine kinase
RAN RAN, member RAS oncogene family
RANGAP1 Ran GTPase activating protein 1
RASSF1 Ras association (RalGDS/AF-6) domain family member 1
RCC1 regulator of chromosome condensation 1
RPS6 ribosomal protein S6
SDC4 syndecan 4
SGOL1 shugoshin-like 1 (S. pombe)
SHCBP1 SHC SH2-domain binding protein 1
SMAD2 SMAD family member 2
SMC1A structural maintenance of chromosomes 1A
SPAG5 sperm associated antigen 5
SPIN1 spindlin 1
STIM1 stromal interaction molecule 1
STK3 serine/threonine kinase 3
STK38 serine/threonine kinase 38
STMN1 stathmin 1
SVIL supervillin
TACC3 transforming, acidic coiled-coil containing protein 3
TBCB tubulin folding cofactor B
TEX14 testis expressed 14
TLX1 T-cell leukemia homeobox 1
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
TP53 tumor protein p53
TP73 tumor protein p73
TPT1 tumor protein, translationally-controlled 1
TTK TTK protein kinase
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase
WWC1 WW and C2 domain containing 1
XPO1 exportin 1
ZWINT ZW10 interacting kinetochore protein