spindle Gene Set

Dataset GO Cellular Component Annotations
Category structural or functional annotations
Type cellular component
Description The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. (Gene Ontology, GO_0005819)
External Link http://amigo.geneontology.org/amigo/term/GO:0005819
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Genes

145 proteins localized to the spindle cellular component from the curated GO Cellular Component Annotations dataset.

Symbol Name
ACOT13 acyl-CoA thioesterase 13
AGBL5 ATP/GTP binding protein-like 5
AKT1 v-akt murine thymoma viral oncogene homolog 1
ANXA11 annexin A11
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2
ARL2BP ADP-ribosylation factor-like 2 binding protein
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
ATAT1 alpha tubulin acetyltransferase 1
ATM ATM serine/threonine kinase
AURKA aurora kinase A
AURKB aurora kinase B
AURKC aurora kinase C
BIRC5 baculoviral IAP repeat containing 5
CAPG capping protein (actin filament), gelsolin-like
CBX1 chromobox homolog 1
CBX3 chromobox homolog 3
CCSAP centriole, cilia and spindle-associated protein
CDC14A cell division cycle 14A
CDC16 cell division cycle 16
CDC20 cell division cycle 20
CDC27 cell division cycle 27
CDC42 cell division cycle 42
CDCA8 cell division cycle associated 8
CDK1 cyclin-dependent kinase 1
CENPF centromere protein F, 350/400kDa
CEP162 centrosomal protein 162kDa
CEP170 centrosomal protein 170kDa
CEP350 centrosomal protein 350kDa
CHAMP1 chromosome alignment maintaining phosphoprotein 1
CLTC clathrin, heavy chain (Hc)
CLTCL1 clathrin, heavy chain-like 1
CPEB1 cytoplasmic polyadenylation element binding protein 1
CRMP1 collapsin response mediator protein 1
CSNK1D casein kinase 1, delta
CSPP1 centrosome and spindle pole associated protein 1
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
CYLD cylindromatosis (turban tumor syndrome)
DCTN3 dynactin 3 (p22)
DIAPH1 diaphanous-related formin 1
DIDO1 death inducer-obliterator 1
DYNLL1 dynein, light chain, LC8-type 1
DYNLT1 dynein, light chain, Tctex-type 1
E4F1 E4F transcription factor 1
ECT2 epithelial cell transforming 2
EFHC1 EF-hand domain (C-terminal) containing 1
EML2 echinoderm microtubule associated protein like 2
EML4 echinoderm microtubule associated protein like 4
ERCC2 excision repair cross-complementation group 2
EVI5 ecotropic viral integration site 5
FAM96B family with sequence similarity 96, member B
FBXO5 F-box protein 5
FMN2 formin 2
GEM GTP binding protein overexpressed in skeletal muscle
GSG2 germ cell associated 2 (haspin)
HAUS2 HAUS augmin-like complex, subunit 2
HAUS3 HAUS augmin-like complex, subunit 3
HAUS4 HAUS augmin-like complex, subunit 4
HAUS5 HAUS augmin-like complex, subunit 5
HAUS6 HAUS augmin-like complex, subunit 6
HAUS7 HAUS augmin-like complex, subunit 7
HEPACAM2 HEPACAM family member 2
HSPB1 heat shock 27kDa protein 1
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
INCENP inner centromere protein antigens 135/155kDa
INVS inversin
JTB jumping translocation breakpoint
KAT2A K(lysine) acetyltransferase 2A
KATNA1 katanin p60 (ATPase containing) subunit A 1
KBTBD8 kelch repeat and BTB (POZ) domain containing 8
KIF11 kinesin family member 11
KIF15 kinesin family member 15
KIF20A kinesin family member 20A
KIF20B kinesin family member 20B
KIF22 kinesin family member 22
KIF23 kinesin family member 23
KIF2B kinesin family member 2B
KIFC1 kinesin family member C1
KLHL22 kelch-like family member 22
KLHL42 kelch-like family member 42
KNSTRN kinetochore-localized astrin/SPAG5 binding protein
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast)
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast)
MAD2L1BP MAD2L1 binding protein
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast)
MAEA macrophage erythroblast attacher
MAK male germ cell-associated kinase
MAP1S microtubule-associated protein 1S
MAP2K5 mitogen-activated protein kinase kinase 5
MAP4 microtubule-associated protein 4
MAP7D1 MAP7 domain containing 1
MAP7D3 MAP7 domain containing 3
MAPK1 mitogen-activated protein kinase 1
MAPRE1 microtubule-associated protein, RP/EB family, member 1
MID1 midline 1
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae)
MTUS1 microtubule associated tumor suppressor 1
MYH10 myosin, heavy chain 10, non-muscle
MYH9 myosin, heavy chain 9, non-muscle
MZT1 mitotic spindle organizing protein 1
MZT2A mitotic spindle organizing protein 2A
MZT2B mitotic spindle organizing protein 2B
NDEL1 nudE neurodevelopment protein 1-like 1
NEDD9 neural precursor cell expressed, developmentally down-regulated 9
NSUN2 NOP2/Sun RNA methyltransferase family, member 2
NUMA1 nuclear mitotic apparatus protein 1
NUP85 nucleoporin 85kDa
PARD3 par-3 family cell polarity regulator
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1
PKD2 polycystic kidney disease 2 (autosomal dominant)
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive)
PKP4 plakophilin 4
PLK1 polo-like kinase 1
PPP2R3C protein phosphatase 2, regulatory subunit B'', gamma
PRC1 protein regulator of cytokinesis 1
PRPF19 pre-mRNA processing factor 19
PSRC1 proline/serine-rich coiled-coil 1
PTP4A1 protein tyrosine phosphatase type IVA, member 1
RACGAP1 Rac GTPase activating protein 1
RB1 retinoblastoma 1
RGS14 regulator of G-protein signaling 14
RIF1 replication timing regulatory factor 1
RPS3 ribosomal protein S3
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2
SEPT12 septin 12
SEPT2 septin 2
SEPT6 septin 6
SEPT7 septin 7
SIRT2 sirtuin 2
SNCG synuclein, gamma (breast cancer-specific protein 1)
SPAG5 sperm associated antigen 5
SPAST spastin
SPECC1L sperm antigen with calponin homology and coiled-coil domains 1-like
SPICE1 spindle and centriole associated protein 1
SPIN1 spindlin 1
STX1B syntaxin 1B
TADA3 transcriptional adaptor 3
TERF1 telomeric repeat binding factor (NIMA-interacting) 1
TPR translocated promoter region, nuclear basket protein
TPX2 TPX2, microtubule-associated
TTK TTK protein kinase
TUBGCP3 tubulin, gamma complex associated protein 3
VRK1 vaccinia related kinase 1
YEATS2 YEATS domain containing 2