spindle Gene Set

Dataset COMPARTMENTS Curated Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The array of microtubules and associated molecules that forms between opposite poles of a eukaryotic cell during mitosis or meiosis and serves to move the duplicated chromosomes apart. (Gene Ontology, GO_0005819)
Similar Terms
Downloads & Tools

Genes

227 proteins localized to the spindle cellular component from the COMPARTMENTS Curated Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
HAUS3 HAUS augmin-like complex, subunit 3 0.663342
KIF20A kinesin family member 20A 0.663342
KIF20B kinesin family member 20B 0.663342
CTDP1 CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1 0.663342
CSNK1D casein kinase 1, delta 0.663342
SGOL1 shugoshin-like 1 (S. pombe) 0.663342
HEPACAM2 HEPACAM family member 2 0.663342
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.663342
LATS1 large tumor suppressor kinase 1 0.663342
LATS2 large tumor suppressor kinase 2 0.663342
PLK1 polo-like kinase 1 0.663342
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.663342
GSG2 germ cell associated 2 (haspin) 0.663342
HAUS2 HAUS augmin-like complex, subunit 2 0.663342
HAUS5 HAUS augmin-like complex, subunit 5 0.663342
HAUS4 HAUS augmin-like complex, subunit 4 0.663342
HAUS7 HAUS augmin-like complex, subunit 7 0.663342
HAUS6 HAUS augmin-like complex, subunit 6 0.663342
HAUS8 HAUS augmin-like complex, subunit 8 0.663342
BIRC5 baculoviral IAP repeat containing 5 0.663342
BIRC6 baculoviral IAP repeat containing 6 0.663342
KNSTRN kinetochore-localized astrin/SPAG5 binding protein 0.663342
KATNA1 katanin p60 (ATPase containing) subunit A 1 0.663342
KIF23 kinesin family member 23 0.663342
KIF2A kinesin heavy chain member 2A 0.663342
TPX2 TPX2, microtubule-associated 0.663342
TPR translocated promoter region, nuclear basket protein 0.663342
CEP44 centrosomal protein 44kDa 0.663342
PRPF19 pre-mRNA processing factor 19 0.663342
CLASP1 cytoplasmic linker associated protein 1 0.663342
CLASP2 cytoplasmic linker associated protein 2 0.663342
KIF11 kinesin family member 11 0.663342
KIF15 kinesin family member 15 0.663342
KIF14 kinesin family member 14 0.663342
PRC1 protein regulator of cytokinesis 1 0.663342
POLB polymerase (DNA directed), beta 0.663342
PSRC1 proline/serine-rich coiled-coil 1 0.663342
NUMA1 nuclear mitotic apparatus protein 1 0.663342
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.663342
TERF1 telomeric repeat binding factor (NIMA-interacting) 1 0.663342
EVI5 ecotropic viral integration site 5 0.663342
TUBG1 tubulin, gamma 1 0.663342
MTCL1 microtubule crosslinking factor 1 0.663342
FAM110C family with sequence similarity 110, member C 0.663342
SPAG5 sperm associated antigen 5 0.663342
CENPV centromere protein V 0.663342
CENPE centromere protein E, 312kDa 0.663342
CENPF centromere protein F, 350/400kDa 0.663342
KLHL22 kelch-like family member 22 0.663342
CEP162 centrosomal protein 162kDa 0.663342
DDX11 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 0.663342
TOPBP1 topoisomerase (DNA) II binding protein 1 0.663342
DDX11L8 DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11 like 8 0.663342
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.663342
CDK1 cyclin-dependent kinase 1 0.663342
PTP4A1 protein tyrosine phosphatase type IVA, member 1 0.663342
ANXA11 annexin A11 0.663342
CUL3 cullin 3 0.663342
TBL1X transducin (beta)-like 1X-linked 0.663342
MAK male germ cell-associated kinase 0.663342
SMC3 structural maintenance of chromosomes 3 0.663342
ARL8B ADP-ribosylation factor-like 8B 0.663342
TUBGCP3 tubulin, gamma complex associated protein 3 0.663342
SEPT12 septin 12 0.663342
CAPN6 calpain 6 0.663342
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 0.663342
WDR62 WD repeat domain 62 0.663342
CEP85 centrosomal protein 85kDa 0.663342
CEP89 centrosomal protein 89kDa 0.663342
UNC119 unc-119 homolog (C. elegans) 0.663342
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.663342
ARL8A ADP-ribosylation factor-like 8A 0.663342
MAD2L1BP MAD2L1 binding protein 0.663342
AUNIP aurora kinase A and ninein interacting protein 0.663342
CLTC clathrin, heavy chain (Hc) 0.663342
PKP4 plakophilin 4 0.663342
TNKS tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 0.663342
UMOD uromodulin 0.663342
SPICE1 spindle and centriole associated protein 1 0.663342
NCOR1 nuclear receptor corepressor 1 0.663342
CDC42 cell division cycle 42 0.663342
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 0.663342
SIRT2 sirtuin 2 0.663342
FBXO5 F-box protein 5 0.663342
CEP19 centrosomal protein 19kDa 0.663342
MZT1 mitotic spindle organizing protein 1 0.663342
KATNB1 katanin p80 (WD repeat containing) subunit B 1 0.663342
CDK5RAP2 CDK5 regulatory subunit associated protein 2 0.663342
CETN1 centrin, EF-hand protein, 1 0.663342
NTRK1 neurotrophic tyrosine kinase, receptor, type 1 0.663342
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 0.663342
ECT2 epithelial cell transforming 2 0.663342
RACGAP1 Rac GTPase activating protein 1 0.663342
JTB jumping translocation breakpoint 0.663342
NPM1 nucleophosmin (nucleolar phosphoprotein B23, numatrin) 0.663342
FAM83D family with sequence similarity 83, member D 0.663342
CHAMP1 chromosome alignment maintaining phosphoprotein 1 0.663342
HAUS1 HAUS augmin-like complex, subunit 1 0.663342
CLTCL1 clathrin, heavy chain-like 1 0.663342
ALMS1 Alstrom syndrome protein 1 0.663342
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.663342
MTUS1 microtubule associated tumor suppressor 1 0.663342
RMDN3 regulator of microtubule dynamics 3 0.663342
MAD2L1P1 MAD2 mitotic arrest deficient-like 1 (yeast) pseudogene 1 0.663342
DYNLL1 dynein, light chain, LC8-type 1 0.663342
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.663342
MAD2L2 MAD2 mitotic arrest deficient-like 2 (yeast) 0.663342
CDCA8 cell division cycle associated 8 0.663342
MAP4 microtubule-associated protein 4 0.663342
NEDD9 neural precursor cell expressed, developmentally down-regulated 9 0.663342
GEM GTP binding protein overexpressed in skeletal muscle 0.663342
ARL2BP ADP-ribosylation factor-like 2 binding protein 0.663342
CKAP5 cytoskeleton associated protein 5 0.663342
CKAP2 cytoskeleton associated protein 2 0.663342
ERCC2 excision repair cross-complementation group 2 0.663342
CBX1 chromobox homolog 1 0.663342
CBX3 chromobox homolog 3 0.663342
PARD3 par-3 family cell polarity regulator 0.663342
FAM96B family with sequence similarity 96, member B 0.663342
SKA3 spindle and kinetochore associated complex subunit 3 0.663342
ODF2 outer dense fiber of sperm tails 2 0.663342
TBCCD1 TBCC domain containing 1 0.663342
KNTC1 kinetochore associated 1 0.663342
ZW10 zw10 kinetochore protein 0.663342
SKA2 spindle and kinetochore associated complex subunit 2 0.663342
SKA1 spindle and kinetochore associated complex subunit 1 0.663342
DYNC1I1 dynein, cytoplasmic 1, intermediate chain 1 0.663342
NDEL1 nudE neurodevelopment protein 1-like 1 0.663342
MAP1S microtubule-associated protein 1S 0.663342
MAP10 microtubule-associated protein 10 0.663342
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.663342
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.663342
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.663342
MMS19 MMS19 nucleotide excision repair homolog (S. cerevisiae) 0.663342
FBF1 Fas (TNFRSF6) binding factor 1 0.663342
DCTN1 dynactin 1 0.663342
ARL3 ADP-ribosylation factor-like 3 0.663342
NDE1 nudE neurodevelopment protein 1 0.663342
RIF1 replication timing regulatory factor 1 0.663342
CEP128 centrosomal protein 128kDa 0.663342
SPAST spastin 0.663342
NUP62 nucleoporin 62kDa 0.663342
POC1B POC1 centriolar protein B 0.663342
POC1A POC1 centriolar protein A 0.663342
SPDL1 spindle apparatus coiled-coil protein 1 0.663342
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.663342
CEP350 centrosomal protein 350kDa 0.663342
PIN4 peptidylprolyl cis/trans isomerase, NIMA-interacting 4 0.663342
AURKA aurora kinase A 0.663342
CCSAP centriole, cilia and spindle-associated protein 0.663342
CDC25B cell division cycle 25B 0.663342
KIF18A kinesin family member 18A 0.663342
NEK7 NIMA-related kinase 7 0.663342
CIAO1 cytosolic iron-sulfur assembly component 1 0.663342
NEK6 NIMA-related kinase 6 0.663342
NUP85 nucleoporin 85kDa 0.663342
AURKC aurora kinase C 0.663342
HSPB1 heat shock 27kDa protein 1 0.663342
CSPP1 centrosome and spindle pole associated protein 1 0.663342
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.663342
MAEA macrophage erythroblast attacher 0.663342
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.663342
INCENP inner centromere protein antigens 135/155kDa 0.663342
PARP4 poly (ADP-ribose) polymerase family, member 4 0.663342
KIF4A kinesin family member 4A 0.663342
RCC2 regulator of chromosome condensation 2 0.663342
AURKB aurora kinase B 0.663342
SBDS Shwachman-Bodian-Diamond syndrome 0.663342
MZT2B mitotic spindle organizing protein 2B 0.663342
CDC14A cell division cycle 14A 0.663342
MZT2A mitotic spindle organizing protein 2A 0.663342
RGS14 regulator of G-protein signaling 14 0.663342
NSUN2 NOP2/Sun RNA methyltransferase family, member 2 0.663342
CEP95 centrosomal protein 95kDa 0.663342
KLHL21 kelch-like family member 21 0.663342
ATAT1 alpha tubulin acetyltransferase 1 0.663342
DYNC1LI1 dynein, cytoplasmic 1, light intermediate chain 1 0.663342
HDAC3 histone deacetylase 3 0.663342
TOPORS topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase 0.237908
CDC20 cell division cycle 20 0.237908
NIN ninein (GSK3B interacting protein) 0.237908
CDC16 cell division cycle 16 0.237908
OR2A4 olfactory receptor, family 2, subfamily A, member 4 0.237908
CEP63 centrosomal protein 63kDa 0.237908
CDC6 cell division cycle 6 0.237908
PKD2 polycystic kidney disease 2 (autosomal dominant) 0.237908
MAPK1 mitogen-activated protein kinase 1 0.237908
TTK TTK protein kinase 0.237908
KIF18B kinesin family member 18B 0.237908
CCNB1 cyclin B1 0.237908
DIAPH1 diaphanous-related formin 1 0.237908
CDC27 cell division cycle 27 0.237908
TUBGCP6 tubulin, gamma complex associated protein 6 0.03318
TUBGCP5 tubulin, gamma complex associated protein 5 0.03318
MYH10 myosin, heavy chain 10, non-muscle 0.03318
SPIN1 spindlin 1 0.03318
EML4 echinoderm microtubule associated protein like 4 0.03318
CTTN cortactin 0.03318
TUBGCP4 tubulin, gamma complex associated protein 4 0.03318
TUBGCP2 tubulin, gamma complex associated protein 2 0.03318
KAT2A K(lysine) acetyltransferase 2A 0.03318
APP amyloid beta (A4) precursor protein 0.03318
MYH9 myosin, heavy chain 9, non-muscle 0.03318
NUBP2 nucleotide binding protein 2 0.03318
AKT1 v-akt murine thymoma viral oncogene homolog 1 0.03318
RB1 retinoblastoma 1 0.03318
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 0.03318
KIF3B kinesin family member 3B 0.03318
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.03318
RPS6KA2 ribosomal protein S6 kinase, 90kDa, polypeptide 2 0.03318
TADA3 transcriptional adaptor 3 0.03318
CAMK2B calcium/calmodulin-dependent protein kinase II beta 0.03318
YEATS2 YEATS domain containing 2 0.03318
FMN2 formin 2 0.03318
ASPM asp (abnormal spindle) homolog, microcephaly associated (Drosophila) 0.03318
KIF22 kinesin family member 22 0.03318
ROCK2 Rho-associated, coiled-coil containing protein kinase 2 0.03318
MAPK14 mitogen-activated protein kinase 14 0.03318
MAP2K5 mitogen-activated protein kinase kinase 5 0.03318
ATM ATM serine/threonine kinase 0.03318
NEIL2 nei endonuclease VIII-like 2 (E. coli) 0.03318
TUBG2 tubulin, gamma 2 0.03318
NUSAP1 nucleolar and spindle associated protein 1 0.03318
E4F1 E4F transcription factor 1 0.03318
MAP9 microtubule-associated protein 9 0.03318
NEK2 NIMA-related kinase 2 0.03318
CEP250 centrosomal protein 250kDa 0.03318