spindle midzone Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description The area in the center of the spindle where the spindle microtubules from opposite poles overlap. (Gene Ontology, GO_0051233)
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Genes

126 proteins co-occuring with the spindle midzone cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
KIF23 kinesin family member 23 2.38696
AURKB aurora kinase B 2.29946
INCENP inner centromere protein antigens 135/155kDa 2.17712
RACGAP1 Rac GTPase activating protein 1 1.89731
ECT2 epithelial cell transforming 2 1.67265
ANLN anillin, actin binding protein 1.64793
PRC1 protein regulator of cytokinesis 1 1.64673
PLK1 polo-like kinase 1 1.58047
KIF20A kinesin family member 20A 1.56959
CENPE centromere protein E, 312kDa 1.5656
KIF4A kinesin family member 4A 1.43895
CDCA8 cell division cycle associated 8 1.4198
BIRC5 baculoviral IAP repeat containing 5 1.34392
PLEKHG6 pleckstrin homology domain containing, family G (with RhoGef domain) member 6 1.12756
CDK1 cyclin-dependent kinase 1 1.08171
KLHL13 kelch-like family member 13 1.06954
KLHL9 kelch-like family member 9 1.06296
AURKC aurora kinase C 1.05035
KRT4 keratin 4, type II 1.03929
KIF18A kinesin family member 18A 1.00547
CCDC69 coiled-coil domain containing 69 0.978074
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 0.934544
CDC14A cell division cycle 14A 0.931245
KATNB1 katanin p80 (WD repeat containing) subunit B 1 0.927483
ARHGAP1 Rho GTPase activating protein 1 0.927013
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.898572
PLK2 polo-like kinase 2 0.890245
CENPF centromere protein F, 350/400kDa 0.886551
LZTS2 leucine zipper, putative tumor suppressor 2 0.849746
SHCBP1 SHC SH2-domain binding protein 1 0.823123
STK31 serine/threonine kinase 31 0.768171
CIB3 calcium and integrin binding family member 3 0.755437
KIF14 kinesin family member 14 0.746381
YPEL5 yippee-like 5 (Drosophila) 0.720351
MAP4 microtubule-associated protein 4 0.698663
KLHL22 kelch-like family member 22 0.678108
ARL8A ADP-ribosylation factor-like 8A 0.675934
DSN1 DSN1, MIS12 kinetochore complex component 0.64915
GAS2L3 growth arrest-specific 2 like 3 0.636723
NAT14 N-acetyltransferase 14 (GCN5-related, putative) 0.636295
CEP55 centrosomal protein 55kDa 0.635868
PBK PDZ binding kinase 0.619255
SNAPC2 small nuclear RNA activating complex, polypeptide 2, 45kDa 0.60655
SVIL supervillin 0.59896
CGGBP1 CGG triplet repeat binding protein 1 0.591812
TBCCD1 TBCC domain containing 1 0.584268
KIF12 kinesin family member 12 0.579251
ARHGAP18 Rho GTPase activating protein 18 0.577999
STARD13 StAR-related lipid transfer (START) domain containing 13 0.575912
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 0.552664
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.540294
MAP2 microtubule-associated protein 2 0.539472
H3F3B H3 histone, family 3B (H3.3B) 0.536183
H3F3A H3 histone, family 3A 0.536183
MAPT microtubule-associated protein tau 0.52675
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 0.517348
TEKT1 tektin 1 0.506757
TPX2 TPX2, microtubule-associated 0.499042
RANBP10 RAN binding protein 10 0.490944
KIF11 kinesin family member 11 0.471609
TEKT2 tektin 2 (testicular) 0.470406
KLHL21 kelch-like family member 21 0.470005
MAD1L1 MAD1 mitotic arrest deficient-like 1 (yeast) 0.466799
CDC20 cell division cycle 20 0.464397
CCNB1 cyclin B1 0.45641
CSPP1 centrosome and spindle pole associated protein 1 0.453621
NUF2 NUF2, NDC80 kinetochore complex component 0.450836
MAPRE1 microtubule-associated protein, RP/EB family, member 1 0.449643
SEPT12 septin 12 0.43696
NUMA1 nuclear mitotic apparatus protein 1 0.419252
CCP110 centriolar coiled coil protein 110kDa 0.398975
DCTN1 dynactin 1 0.395098
MYL12A myosin, light chain 12A, regulatory, non-sarcomeric 0.39471
CEP57 centrosomal protein 57kDa 0.393549
CENPB centromere protein B, 80kDa 0.388909
MAD2L1P1 MAD2 mitotic arrest deficient-like 1 (yeast) pseudogene 1 0.386208
SSNA1 Sjogren syndrome nuclear autoantigen 1 0.386208
KCNJ11 potassium channel, inwardly rectifying subfamily J, member 11 0.383124
NBL1 neuroblastoma 1, DAN family BMP antagonist 0.380429
SKA3 spindle and kinetochore associated complex subunit 3 0.378507
CNTLN centlein, centrosomal protein 0.377354
KIFC3 kinesin family member C3 0.371599
ZW10 zw10 kinetochore protein 0.366241
TUBA1A tubulin, alpha 1a 0.360133
NUSAP1 nucleolar and spindle associated protein 1 0.359371
NDC80 NDC80 kinetochore complex component 0.349105
CUL3 cullin 3 0.340773
SPAST spastin 0.340395
VAMP8 vesicle-associated membrane protein 8 0.335864
SEH1L SEH1-like (S. cerevisiae) 0.330213
RANBP9 RAN binding protein 9 0.32195
ANXA11 annexin A11 0.320451
SEPT3 septin 3 0.310358
RIC8A RIC8 guanine nucleotide exchange factor A 0.307377
PPP1R7 protein phosphatase 1, regulatory subunit 7 0.304027
APITD1 apoptosis-inducing, TAF9-like domain 1 0.297713
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.29586
SEPT5 septin 5 0.287352
FMN2 formin 2 0.271533
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) 0.265311
CLASP1 cytoplasmic linker associated protein 1 0.264581
SPAG5 sperm associated antigen 5 0.257289
ZWILCH zwilch kinetochore protein 0.242437
STIL SCL/TAL1 interrupting locus 0.240276
FMN1 formin 1 0.238837
STRA8 stimulated by retinoic acid 8 0.225622
GAS2 growth arrest-specific 2 0.224913
PTTG1 pituitary tumor-transforming 1 0.222436
LATS2 large tumor suppressor kinase 2 0.222083
LIMK2 LIM domain kinase 2 0.208137
PLK3 polo-like kinase 3 0.205399
KIF3B kinesin family member 3B 0.203022
RTKN rhotekin 0.200663
ARPC3 actin related protein 2/3 complex, subunit 3, 21kDa 0.19601
SEPT2 septin 2 0.194371
PCNT pericentrin 0.190175
DNAH14 dynein, axonemal, heavy chain 14 0.189222
DNAH12 dynein, axonemal, heavy chain 12 0.189222
KIF2A kinesin heavy chain member 2A 0.186087
RUVBL2 RuvB-like AAA ATPase 2 0.173543
DNAH5 dynein, axonemal, heavy chain 5 0.16935
SEPT6 septin 6 0.166405
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.165463
FZR1 fizzy/cell division cycle 20 related 1 (Drosophila) 0.160456
MCPH1 microcephalin 1 0.160254
APOLD1 apolipoprotein L domain containing 1 0.159074