spindle microtubule Gene Set

Dataset COMPARTMENTS Text-mining Protein Localization Evidence Scores
Category structural or functional annotations
Type cellular component
Description Any microtubule that is part of a mitotic or meiotic spindle; anchored at one spindle pole. (Gene Ontology, GO_0005876)
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Genes

236 proteins co-occuring with the spindle microtubule cellular component in abstracts of biomedical publications from the COMPARTMENTS Text-mining Protein Localization Evidence Scores dataset.

Symbol Name Standardized Value
AURKB aurora kinase B 2.08817
CENPE centromere protein E, 312kDa 2.01412
NDC80 NDC80 kinetochore complex component 1.89662
BUB1B BUB1 mitotic checkpoint serine/threonine kinase B 1.74829
BUB1 BUB1 mitotic checkpoint serine/threonine kinase 1.56845
NUMA1 nuclear mitotic apparatus protein 1 1.51469
KIF11 kinesin family member 11 1.51299
KIF18A kinesin family member 18A 1.48136
NUF2 NUF2, NDC80 kinetochore complex component 1.42993
CASC5 cancer susceptibility candidate 5 1.39628
PLK1 polo-like kinase 1 1.38516
SPC24 SPC24, NDC80 kinetochore complex component 1.36747
INCENP inner centromere protein antigens 135/155kDa 1.35047
SKA1 spindle and kinetochore associated complex subunit 1 1.32817
KIF2B kinesin family member 2B 1.30497
DCTN1 dynactin 1 1.30228
KIF2A kinesin heavy chain member 2A 1.29585
BUB3 BUB3 mitotic checkpoint protein 1.29585
ZW10 zw10 kinetochore protein 1.28623
SPC25 SPC25, NDC80 kinetochore complex component 1.2793
DLGAP5 discs, large (Drosophila) homolog-associated protein 5 1.25706
CENPH centromere protein H 1.25601
KIF18B kinesin family member 18B 1.23922
TPX2 TPX2, microtubule-associated 1.22672
MIS12 MIS12 kinetochore complex component 1.17209
SGOL1 shugoshin-like 1 (S. pombe) 1.16184
KIF2C kinesin family member 2C 1.16133
CENPC centromere protein C 1.14494
CLASP1 cytoplasmic linker associated protein 1 1.13932
CDK1 cyclin-dependent kinase 1 1.11021
CDC20 cell division cycle 20 1.1097
TUBA1A tubulin, alpha 1a 1.08577
SKA2 spindle and kinetochore associated complex subunit 2 1.08272
SKA3 spindle and kinetochore associated complex subunit 3 1.08272
CKAP5 cytoskeleton associated protein 5 1.07917
ZWILCH zwilch kinetochore protein 1.03879
CENPF centromere protein F, 350/400kDa 1.03378
KIF4A kinesin family member 4A 1.03228
PCNT pericentrin 1.00744
NEDD1 neural precursor cell expressed, developmentally down-regulated 1 1.00103
CENPT centromere protein T 0.993183
ZNF207 zinc finger protein 207 0.98683
MAP4 microtubule-associated protein 4 0.97953
PTTG1 pituitary tumor-transforming 1 0.960707
ZWINT ZW10 interacting kinetochore protein 0.958789
HAUS6 HAUS augmin-like complex, subunit 6 0.924197
CENPL centromere protein L 0.889321
FAM83D family with sequence similarity 83, member D 0.871806
ANLN anillin, actin binding protein 0.846991
MAD2L1P1 MAD2 mitotic arrest deficient-like 1 (yeast) pseudogene 1 0.812111
CCNB1 cyclin B1 0.809817
MISP mitotic spindle positioning 0.808441
CCP110 centriolar coiled coil protein 110kDa 0.803396
MAPT microtubule-associated protein tau 0.792396
MAP2 microtubule-associated protein 2 0.782326
APITD1 apoptosis-inducing, TAF9-like domain 1 0.782326
TACC3 transforming, acidic coiled-coil containing protein 3 0.763162
ESPL1 extra spindle pole bodies homolog 1 (S. cerevisiae) 0.757253
HIST2H3PS2 histone cluster 2, H3, pseudogene 2 0.742769
H3F3A H3 histone, family 3A 0.738263
H3F3B H3 histone, family 3B (H3.3B) 0.738263
CNTLN centlein, centrosomal protein 0.726599
PPP1R7 protein phosphatase 1, regulatory subunit 7 0.725258
CDCA8 cell division cycle associated 8 0.725258
KIZ kizuna centrosomal protein 0.716346
MAD2L1 MAD2 mitotic arrest deficient-like 1 (yeast) 0.703507
VPS72 vacuolar protein sorting 72 homolog (S. cerevisiae) 0.679849
BIRC5 baculoviral IAP repeat containing 5 0.677238
KIF23 kinesin family member 23 0.659913
CENPQ centromere protein Q 0.652159
H3F3C H3 histone, family 3C 0.638861
CLIP1 CAP-GLY domain containing linker protein 1 0.620954
CIB3 calcium and integrin binding family member 3 0.616285
RAN RAN, member RAS oncogene family 0.611625
STMN1 stathmin 1 0.605706
CEP57 centrosomal protein 57kDa 0.603596
CENPN centromere protein N 0.597697
MTUS2 microtubule associated tumor suppressor candidate 2 0.591392
CENPW centromere protein W 0.588037
CEP72 centrosomal protein 72kDa 0.588037
SPAG8 sperm associated antigen 8 0.579669
PRC1 protein regulator of cytokinesis 1 0.570913
CENPU centromere protein U 0.569248
NUSAP1 nucleolar and spindle associated protein 1 0.566338
NSL1 NSL1, MIS12 kinetochore complex component 0.560943
CEP41 centrosomal protein 41kDa 0.559285
TUBGCP3 tubulin, gamma complex associated protein 3 0.558457
SPAG5 sperm associated antigen 5 0.558042
RAD21 RAD21 homolog (S. pombe) 0.557629
DCTN2 dynactin 2 (p50) 0.546885
NUDCD3 NudC domain containing 3 0.545648
STRA13 stimulated by retinoic acid 13 0.545236
EML3 echinoderm microtubule associated protein like 3 0.53454
ANAPC16 anaphase promoting complex subunit 16 0.521841
PPP2R4 protein phosphatase 2A activator, regulatory subunit 4 0.517756
CENPB centromere protein B, 80kDa 0.514085
KIF15 kinesin family member 15 0.508383
NAT14 N-acetyltransferase 14 (GCN5-related, putative) 0.503912
DIAPH2 diaphanous-related formin 2 0.486904
TBL1XR1 transducin (beta)-like 1 X-linked receptor 1 0.4865
BCAS2 breast carcinoma amplified sequence 2 0.483273
PINX1 PIN2/TERF1 interacting, telomerase inhibitor 1 0.464798
DYNC1H1 dynein, cytoplasmic 1, heavy chain 1 0.463598
TEX14 testis expressed 14 0.461199
CENPA centromere protein A 0.4608
THOC7 THO complex 7 0.443689
FMN2 formin 2 0.439333
PARD6A par-6 family cell polarity regulator alpha 0.438146
MAP1S microtubule-associated protein 1S 0.43617
SKP1 S-phase kinase-associated protein 1 0.432618
GPR162 G protein-coupled receptor 162 0.431041
AMT aminomethyltransferase 0.425924
BLOC1S2 biogenesis of lysosomal organelles complex-1, subunit 2 0.42396
NUBP1 nucleotide binding protein 1 0.417685
SPDL1 spindle apparatus coiled-coil protein 1 0.409869
NUBP2 nucleotide binding protein 2 0.398975
AURKC aurora kinase C 0.395485
DNAH12 dynein, axonemal, heavy chain 12 0.386208
DNAH14 dynein, axonemal, heavy chain 14 0.386208
KIF24 kinesin family member 24 0.383895
PDCL2 phosducin-like 2 0.374666
FIGN fidgetin 0.370067
DYNLT3 dynein, light chain, Tctex-type 3 0.367771
CEP170 centrosomal protein 170kDa 0.367388
CKAP2 cytoskeleton associated protein 2 0.364713
MAPK6 mitogen-activated protein kinase 6 0.361659
DNAH5 dynein, axonemal, heavy chain 5 0.359752
IFT74 intraflagellar transport 74 0.356324
HMMR hyaluronan-mediated motility receptor (RHAMM) 0.354802
GOLGA4 golgin A4 0.340773
CALM3 calmodulin 3 (phosphorylase kinase, delta) 0.337373
CALM2 calmodulin 2 (phosphorylase kinase, delta) 0.336996
CALM1 calmodulin 1 (phosphorylase kinase, delta) 0.336619
KIF5B kinesin family member 5B 0.333225
CSPP1 centrosome and spindle pole associated protein 1 0.330589
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) 0.328332
STAC SH3 and cysteine rich domain 0.319328
FTMT ferritin mitochondrial 0.304399
DNAH9 dynein, axonemal, heavy chain 9 0.303283
ECT2 epithelial cell transforming 2 0.302912
KIF22 kinesin family member 22 0.300682
NDEL1 nudE neurodevelopment protein 1-like 1 0.293637
SPIN1 spindlin 1 0.287352
TACC2 transforming, acidic coiled-coil containing protein 2 0.286614
KIF14 kinesin family member 14 0.277406
TACC1 transforming, acidic coiled-coil containing protein 1 0.277406
TBCD tubulin folding cofactor D 0.271533
APC adenomatous polyposis coli 0.262755
TP53 tumor protein p53 0.260931
NIN ninein (GSK3B interacting protein) 0.252202
CDC42 cell division cycle 42 0.251114
FMN1 formin 1 0.249302
SMC4 structural maintenance of chromosomes 4 0.238837
KIF1C kinesin family member 1C 0.233817
NEK7 NIMA-related kinase 7 0.230601
CDC27 cell division cycle 27 0.230245
KIF13B kinesin family member 13B 0.229532
SGOL2 shugoshin-like 2 (S. pombe) 0.228464
RASSF1 Ras association (RalGDS/AF-6) domain family member 1 0.227397
DYNLT1 dynein, light chain, Tctex-type 1 0.213669
TUBGCP2 tubulin, gamma complex associated protein 2 0.211587
INSC inscuteable homolog (Drosophila) 0.21124
TUBG1 tubulin, gamma 1 0.203022
KIF1A kinesin family member 1A 0.202684
PLK2 polo-like kinase 2 0.200328
LSM14A LSM14A, SCD6 homolog A (S. cerevisiae) 0.19733
RUVBL1 RuvB-like AAA ATPase 1 0.195025
NCBP1 nuclear cap binding protein subunit 1, 80kDa 0.1921
ARR3 arrestin 3, retinal (X-arrestin) 0.191135
RAE1 ribonucleic acid export 1 0.18516
TPR translocated promoter region, nuclear basket protein 0.18516
ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 0.184853
COLEC12 collectin sub-family member 12 0.183935
NEK6 NIMA-related kinase 6 0.183631
MTAP methylthioadenosine phosphorylase 0.182422
KIFAP3 kinesin-associated protein 3 0.180045
AURKA aurora kinase A 0.177154
MARK2 MAP/microtubule affinity-regulating kinase 2 0.175745
HIST1H2AJ histone cluster 1, H2aj 0.17141
H2AFJ H2A histone family, member J 0.17141
HIST1H2AD histone cluster 1, H2ad 0.17141
HIST1H2AH histone cluster 1, H2ah 0.171149
HIST1H2AM histone cluster 1, H2am 0.171149
HIST1H2AG histone cluster 1, H2ag 0.170371
H2AFY2 H2A histone family, member Y2 0.169099
HIST1H2AE histone cluster 1, H2ae 0.168847
HIST1H2AB histone cluster 1, H2ab 0.168847
H2AFV H2A histone family, member V 0.168598
H2AFB1 H2A histone family, member B1 0.166643
CEP192 centrosomal protein 192kDa 0.166167
NEK9 NIMA-related kinase 9 0.165932
SF3A2 splicing factor 3a, subunit 2, 66kDa 0.165463
H2AFB2 H2A histone family, member B2 0.16477
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit 0.162763
H2AFY H2A histone family, member Y 0.162763
DPYSL3 dihydropyrimidinase-like 3 0.160254
CCDC62 coiled-coil domain containing 62 0.135034
CRMP1 collapsin response mediator protein 1 0.134812
ARL2 ADP-ribosylation factor-like 2 0.133986
PAK2 p21 protein (Cdc42/Rac)-activated kinase 2 0.133393
PAK4 p21 protein (Cdc42/Rac)-activated kinase 4 0.133372
CNOT1 CCR4-NOT transcription complex, subunit 1 0.132212
NDE1 nudE neurodevelopment protein 1 0.131907
EEA1 early endosome antigen 1 0.131519
KNTC1 kinetochore associated 1 0.131469
NDRG1 N-myc downstream regulated 1 0.131332
CAMKK2 calcium/calmodulin-dependent protein kinase kinase 2, beta 0.131
SMC1A structural maintenance of chromosomes 1A 0.13087
MYO10 myosin X 0.130645
CLASP2 cytoplasmic linker associated protein 2 0.130632
GPR176 G protein-coupled receptor 176 0.13007
SUN1 Sad1 and UNC84 domain containing 1 0.129713
WAPAL wings apart-like homolog (Drosophila) 0.129699
ERG v-ets avian erythroblastosis virus E26 oncogene homolog 0.1293
TXNDC9 thioredoxin domain containing 9 0.129255
ARHGEF7 Rho guanine nucleotide exchange factor (GEF) 7 0.129072
SEPT5 septin 5 0.12901
RGPD3 RANBP2-like and GRIP domain containing 3 0.128538
UBE2D2 ubiquitin-conjugating enzyme E2D 2 0.128196
KAT2B K(lysine) acetyltransferase 2B 0.128163
SCIN scinderin 0.127809
RPS6KA1 ribosomal protein S6 kinase, 90kDa, polypeptide 1 0.127792
TMOD4 tropomodulin 4 (muscle) 0.127584
CALB2 calbindin 2 0.126939
USP7 ubiquitin specific peptidase 7 (herpes virus-associated) 0.126809
CYLD cylindromatosis (turban tumor syndrome) 0.126158
LIMK1 LIM domain kinase 1 0.125819
LAMP1 lysosomal-associated membrane protein 1 0.125449
MLLT4 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 4 0.123941
RANBP2 RAN binding protein 2 0.12387
NUMB numb homolog (Drosophila) 0.123533
RANGAP1 Ran GTPase activating protein 1 0.123411
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase 0.123288
PLEK pleckstrin 0.123138
DYNLL1 dynein, light chain, LC8-type 1 0.122335
NUP107 nucleoporin 107kDa 0.12201