spinal stenosis Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A bone deterioration disease that has_material_basis_in bony spurs, disc degeneration, or thickened ligaments which results_in narrowing located_in spinal cord. (Human Disease Ontology, DOID_6725)
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Genes

87 genes co-occuring with the disease spinal stenosis in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) 2.08359
COL6A1 collagen, type VI, alpha 1 1.76683
CCDC34 coiled-coil domain containing 34 1.35028
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 1.31362
BMP7 bone morphogenetic protein 7 1.28435
TSSK4 testis-specific serine kinase 4 1.23646
KLK8 kallikrein-related peptidase 8 1.22605
CALCA calcitonin-related polypeptide alpha 1.16692
NFYC nuclear transcription factor Y, gamma 1.12319
DCD dermcidin 1.12235
TRIM68 tripartite motif containing 68 1.07194
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 1.02608
TMTC1 transmembrane and tetratricopeptide repeat containing 1 0.990222
ACAN aggrecan 0.951187
COL9A2 collagen, type IX, alpha 2 0.949519
HSF4 heat shock transcription factor 4 0.907731
VAT1 vesicle amine transport 1 0.901978
IVD isovaleryl-CoA dehydrogenase 0.827819
C1ORF167 chromosome 1 open reading frame 167 0.827409
LAX1 lymphocyte transmembrane adaptor 1 0.806898
IDS iduronate 2-sulfatase 0.788442
PIAS2 protein inhibitor of activated STAT, 2 0.753713
MAPK1IP1L mitogen-activated protein kinase 1 interacting protein 1-like 0.742735
ARSD arylsulfatase D 0.733001
GALNS galactosamine (N-acetyl)-6-sulfatase 0.720461
AMIGO2 adhesion molecule with Ig-like domain 2 0.71078
ADGRL4 adhesion G protein-coupled receptor L4 0.66914
COL9A3 collagen, type IX, alpha 3 0.66755
CD2BP2 CD2 (cytoplasmic tail) binding protein 2 0.658422
BMP2 bone morphogenetic protein 2 0.650113
ARSE arylsulfatase E (chondrodysplasia punctata 1) 0.621008
COL9A1 collagen, type IX, alpha 1 0.594064
FBXW2 F-box and WD repeat domain containing 2 0.583941
KMO kynurenine 3-monooxygenase (kynurenine 3-hydroxylase) 0.578106
POMP proteasome maturation protein 0.569163
LSR lipolysis stimulated lipoprotein receptor 0.544705
HTRA1 HtrA serine peptidase 1 0.531928
MIA melanoma inhibitory activity 0.510728
CRP C-reactive protein, pentraxin-related 0.474119
DST dystonin 0.465416
COL11A2P1 collagen, type XI, alpha 2 pseudogene 1 0.461261
COL11A2 collagen, type XI, alpha 2 0.460883
THBS2 thrombospondin 2 0.457864
GHR growth hormone receptor 0.454093
FGF9 fibroblast growth factor 9 0.43941
BBS4 Bardet-Biedl syndrome 4 0.434148
PPARGC1B peroxisome proliferator-activated receptor gamma, coactivator 1 beta 0.428516
BBC3 BCL2 binding component 3 0.413901
HMGA2 high mobility group AT-hook 2 0.408666
TRPC3 transient receptor potential cation channel, subfamily C, member 3 0.404557
COL11A1 collagen, type XI, alpha 1 0.402318
SHOX short stature homeobox 0.392257
ALPPL2 alkaline phosphatase, placental-like 2 0.390769
ALPP alkaline phosphatase, placental 0.390397
ALPL alkaline phosphatase, liver/bone/kidney 0.390025
BGLAP bone gamma-carboxyglutamate (gla) protein 0.388909
MMP3 matrix metallopeptidase 3 0.384079
TSKU tsukushi, small leucine rich proteoglycan 0.372587
AMY2A amylase, alpha 2A (pancreatic) 0.368149
LARGE like-glycosyltransferase 0.364085
OR10K1 olfactory receptor, family 10, subfamily K, member 1 0.351187
MARK3 MAP/microtubule affinity-regulating kinase 3 0.347511
MARK2 MAP/microtubule affinity-regulating kinase 2 0.346777
SP7 Sp7 transcription factor 0.332852
CALCR calcitonin receptor 0.328105
TBX1 T-box 1 0.313915
ECE1 endothelin converting enzyme 1 0.312464
FTH1 ferritin, heavy polypeptide 1 0.30631
SLC35B2 solute carrier family 35 (adenosine 3'-phospho 5'-phosphosulfate transporter), member B2 0.300894
FGFR3 fibroblast growth factor receptor 3 0.297651
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 0.274732
TIMP2 TIMP metallopeptidase inhibitor 2 0.255241
IDUA iduronidase, alpha-L- 0.243995
DNASE1 deoxyribonuclease I 0.241546
TNFRSF1B tumor necrosis factor receptor superfamily, member 1B 0.236312
EPHA4 EPH receptor A4 0.231795
SIRT2 sirtuin 2 0.231448
TGFB1 transforming growth factor, beta 1 0.225917
NDUFA5 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5 0.210589
NDUFS4 NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase) 0.206248
GPANK1 G patch domain and ankyrin repeats 1 0.201308
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 0.183248
CREM cAMP responsive element modulator 0.17896
CNTF ciliary neurotrophic factor 0.172799
GOLPH3 golgi phosphoprotein 3 (coat-protein) 0.165655
PGRMC1 progesterone receptor membrane component 1 0.163729
C7ORF49 chromosome 7 open reading frame 49 0.161716