sphingolipid metabolism Gene Set

Dataset KEGG Pathways
Category structural or functional annotations
Type pathway
Description The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). (Gene Ontology, GO_0006665)
External Link http://www.genome.jp/kegg/pathway/hsa/hsa00600.html
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Genes

36 proteins participating in the sphingolipid metabolism pathway from the KEGG Pathways dataset.

Symbol Name
ARSA arylsulfatase A
ARSD arylsulfatase D
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
B4GALT6 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6
CERK ceramide kinase
DEGS1 delta(4)-desaturase, sphingolipid 1
DEGS2 delta(4)-desaturase, sphingolipid 2
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
GAL3ST1 galactose-3-O-sulfotransferase 1
GALC galactosylceramidase
GBA glucosidase, beta, acid
GLA galactosidase, alpha
GLB1 galactosidase, beta 1
LCT lactase
NEU1 sialidase 1 (lysosomal sialidase)
NEU2 sialidase 2 (cytosolic sialidase)
NEU3 sialidase 3 (membrane sialidase)
NEU4 sialidase 4
PPAP2A phosphatidic acid phosphatase type 2A
PPAP2B phosphatidic acid phosphatase type 2B
PPAP2C phosphatidic acid phosphatase type 2C
SGMS1 sphingomyelin synthase 1
SGMS2 sphingomyelin synthase 2
SGPP1 sphingosine-1-phosphate phosphatase 1
SGPP2 sphingosine-1-phosphate phosphatase 2
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
UGCG UDP-glucose ceramide glucosyltransferase
UGT8 UDP glycosyltransferase 8