sphingolipid metabolic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways involving sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). (Gene Ontology, GO_0006665)
External Link http://amigo.geneontology.org/amigo/term/GO:0006665
Similar Terms
Downloads & Tools

Genes

125 genes participating in the sphingolipid metabolic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
A3GALT2 alpha 1,3-galactosyltransferase 2
A4GALT alpha 1,4-galactosyltransferase
ACER1 alkaline ceramidase 1
ACER2 alkaline ceramidase 2
ACER3 alkaline ceramidase 3
AGK acylglycerol kinase
ALDH5A1 aldehyde dehydrogenase 5 family, member A1
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOXE3 arachidonate lipoxygenase 3
ARSA arylsulfatase A
ARSB arylsulfatase B
ARSD arylsulfatase D
ARSE arylsulfatase E (chondrodysplasia punctata 1)
ARSF arylsulfatase F
ARSG arylsulfatase G
ARSH arylsulfatase family, member H
ARSI arylsulfatase family, member I
ARSJ arylsulfatase family, member J
ARSK arylsulfatase family, member K
ARV1 ARV1 homolog (S. cerevisiae)
ASAH1 N-acylsphingosine amidohydrolase (acid ceramidase) 1
ASAH2 N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
BAX BCL2-associated X protein
CERK ceramide kinase
CERS1 ceramide synthase 1
CERS2 ceramide synthase 2
CERS3 ceramide synthase 3
CERS4 ceramide synthase 4
CERS5 ceramide synthase 5
CERS6 ceramide synthase 6
CLN3 ceroid-lipofuscinosis, neuronal 3
CLN6 ceroid-lipofuscinosis, neuronal 6, late infantile, variant
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CREM cAMP responsive element modulator
CSNK1G2 casein kinase 1, gamma 2
CTSA cathepsin A
DEGS1 delta(4)-desaturase, sphingolipid 1
DEGS2 delta(4)-desaturase, sphingolipid 2
ELOVL1 ELOVL fatty acid elongase 1
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7
FA2H fatty acid 2-hydroxylase
FAM57B family with sequence similarity 57, member B
GAL3ST1 galactose-3-O-sulfotransferase 1
GALC galactosylceramidase
GBA glucosidase, beta, acid
GBA2 glucosidase, beta (bile acid) 2
GBA3 glucosidase, beta, acid 3 (gene/pseudogene)
GLA galactosidase, alpha
GLB1 galactosidase, beta 1
GM2A GM2 ganglioside activator
HACD2 3-hydroxyacyl-CoA dehydratase 2
HEXA hexosaminidase A (alpha polypeptide)
HEXB hexosaminidase B (beta polypeptide)
HTRA2 HtrA serine peptidase 2
ITGB8 integrin, beta 8
KDSR 3-ketodihydrosphingosine reductase
KIT v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog
LARGE like-glycosyltransferase
NAGA N-acetylgalactosaminidase, alpha-
NEU1 sialidase 1 (lysosomal sialidase)
NEU2 sialidase 2 (cytosolic sialidase)
NEU3 sialidase 3 (membrane sialidase)
NEU4 sialidase 4
NSMAF neutral sphingomyelinase (N-SMase) activation associated factor
ORMDL1 ORMDL sphingolipid biosynthesis regulator 1
ORMDL2 ORMDL sphingolipid biosynthesis regulator 2
ORMDL3 ORMDL sphingolipid biosynthesis regulator 3
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PLA2G15 phospholipase A2, group XV
PPAP2A phosphatidic acid phosphatase type 2A
PPAP2B phosphatidic acid phosphatase type 2B
PPAP2C phosphatidic acid phosphatase type 2C
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PPP2CA protein phosphatase 2, catalytic subunit, alpha isozyme
PPP2R1A protein phosphatase 2, regulatory subunit A, alpha
PPT1 palmitoyl-protein thioesterase 1
PRKD1 protein kinase D1
PSAP prosaposin
PSAPL1 prosaposin-like 1 (gene/pseudogene)
SAMD8 sterile alpha motif domain containing 8
SERINC1 serine incorporator 1
SERINC2 serine incorporator 2
SERINC3 serine incorporator 3
SERINC5 serine incorporator 5
SFTPB surfactant protein B
SGMS1 sphingomyelin synthase 1
SGMS2 sphingomyelin synthase 2
SGPL1 sphingosine-1-phosphate lyase 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SGPP2 sphingosine-1-phosphate phosphatase 2
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPD3 sphingomyelin phosphodiesterase 3, neutral membrane (neutral sphingomyelinase II)
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
SMPDL3A sphingomyelin phosphodiesterase, acid-like 3A
SMPDL3B sphingomyelin phosphodiesterase, acid-like 3B
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SPNS2 spinster homolog 2 (Drosophila)
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SPTSSA serine palmitoyltransferase, small subunit A
SPTSSB serine palmitoyltransferase, small subunit B
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST6GALNAC3 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
STS steroid sulfatase (microsomal), isozyme S
SUMF1 sulfatase modifying factor 1
TEX2 testis expressed 2
TH tyrosine hydroxylase
UGCG UDP-glucose ceramide glucosyltransferase
UGT8 UDP glycosyltransferase 8
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C