sphingolipid biosynthetic process Gene Set

Dataset GO Biological Process Annotations
Category structural or functional annotations
Type biological process
Description The chemical reactions and pathways resulting in the formation of sphingolipids, any of a class of lipids containing the long-chain amine diol sphingosine or a closely related base (a sphingoid). (Gene Ontology, GO_0030148)
External Link http://amigo.geneontology.org/amigo/term/GO:0030148
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Genes

63 genes participating in the sphingolipid biosynthetic process biological process from the curated GO Biological Process Annotations dataset.

Symbol Name
A3GALT2 alpha 1,3-galactosyltransferase 2
A4GALT alpha 1,4-galactosyltransferase
ACER1 alkaline ceramidase 1
ACER2 alkaline ceramidase 2
ACER3 alkaline ceramidase 3
AGK acylglycerol kinase
ALOX12B arachidonate 12-lipoxygenase, 12R type
ALOXE3 arachidonate lipoxygenase 3
B4GALNT1 beta-1,4-N-acetyl-galactosaminyl transferase 1
CERS1 ceramide synthase 1
CERS2 ceramide synthase 2
CERS3 ceramide synthase 3
CERS4 ceramide synthase 4
CERS5 ceramide synthase 5
CERS6 ceramide synthase 6
CLN8 ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
COL4A3BP collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
CSNK1G2 casein kinase 1, gamma 2
DEGS1 delta(4)-desaturase, sphingolipid 1
DEGS2 delta(4)-desaturase, sphingolipid 2
ELOVL1 ELOVL fatty acid elongase 1
FAM57B family with sequence similarity 57, member B
GAL3ST1 galactose-3-O-sulfotransferase 1
GBA glucosidase, beta, acid
HACD2 3-hydroxyacyl-CoA dehydratase 2
KDSR 3-ketodihydrosphingosine reductase
LARGE like-glycosyltransferase
P2RX1 purinergic receptor P2X, ligand gated ion channel, 1
P2RX7 purinergic receptor P2X, ligand gated ion channel, 7
PPAP2A phosphatidic acid phosphatase type 2A
PPAP2B phosphatidic acid phosphatase type 2B
PPAP2C phosphatidic acid phosphatase type 2C
PPM1L protein phosphatase, Mg2+/Mn2+ dependent, 1L
PRKD1 protein kinase D1
SAMD8 sterile alpha motif domain containing 8
SGMS1 sphingomyelin synthase 1
SGMS2 sphingomyelin synthase 2
SGPL1 sphingosine-1-phosphate lyase 1
SGPP1 sphingosine-1-phosphate phosphatase 1
SGPP2 sphingosine-1-phosphate phosphatase 2
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal
SMPD2 sphingomyelin phosphodiesterase 2, neutral membrane (neutral sphingomyelinase)
SMPD4 sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)
SPHK1 sphingosine kinase 1
SPHK2 sphingosine kinase 2
SPTLC1 serine palmitoyltransferase, long chain base subunit 1
SPTLC2 serine palmitoyltransferase, long chain base subunit 2
SPTLC3 serine palmitoyltransferase, long chain base subunit 3
SPTSSA serine palmitoyltransferase, small subunit A
SPTSSB serine palmitoyltransferase, small subunit B
ST3GAL5 ST3 beta-galactoside alpha-2,3-sialyltransferase 5
ST6GALNAC5 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 5
ST6GALNAC6 ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
ST8SIA1 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
ST8SIA2 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
ST8SIA6 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
UGCG UDP-glucose ceramide glucosyltransferase
UGT8 UDP glycosyltransferase 8
VAPA VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa
VAPB VAMP (vesicle-associated membrane protein)-associated protein B and C