speech disorder Gene Set

Dataset GWASdb SNP-Disease Associations
Category disease or phenotype associations
Type disease
Description A communication disorder that involves difficulty with the act of speech production. (Human Disease Ontology, DOID_92)
External Link http://jjwanglab.org/gwasdb/gwasdb2/gwasdb2/go_trait/DOID:92
Similar Terms
Downloads & Tools

Genes

56 genes associated with the disease speech disorder in GWAS and other genetic association datasets from the GWASdb SNP-Disease Associations dataset.

Symbol Name Standardized Value
DAZAP1 DAZ associated protein 1 1.19386
SLC9C2 solute carrier family 9, member C2 (putative) 1.138
PRKCH protein kinase C, eta 1.10764
CDK1 cyclin-dependent kinase 1 1.10764
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein 1.04846
FAM155A family with sequence similarity 155, member A 1.00407
ALOX5AP arachidonate 5-lipoxygenase-activating protein 1.00407
UBL3 ubiquitin-like 3 0.986376
NLRP3 NLR family, pyrin domain containing 3 0.986376
OBP2A odorant binding protein 2A 0.938237
SLC39A8 solute carrier family 39 (zinc transporter), member 8 0.93638
OXR1 oxidation resistance 1 0.92437
ELP4 elongator acetyltransferase complex subunit 4 0.920453
FAM126A family with sequence similarity 126, member A 0.918185
ENOX1 ecto-NOX disulfide-thiol exchanger 1 0.912987
RCAN3 RCAN family member 3 0.912987
PIAS4 protein inhibitor of activated STAT, 4 0.910724
CAMTA1 calmodulin binding transcription activator 1 0.898875
PTPRM protein tyrosine phosphatase, receptor type, M 0.892579
CRBN cereblon 0.890183
SPATA13 spermatogenesis associated 13 0.877977
COX7B2 cytochrome c oxidase subunit VIIb2 0.873424
HHLA2 HERV-H LTR-associating 2 0.87287
LRBA LPS-responsive vesicle trafficking, beach and anchor containing 0.870688
RNF13 ring finger protein 13 0.863433
CLSTN2 calsyntenin 2 0.852796
DPYSL3 dihydropyrimidinase-like 3 0.850837
ABCA13 ATP-binding cassette, sub-family A (ABC1), member 13 0.844278
CDH8 cadherin 8, type 2 0.840723
LRPPRC leucine-rich pentatricopeptide repeat containing 0.829434
RAMP3 receptor (G protein-coupled) activity modifying protein 3 0.812707
ADAMTS8 ADAM metallopeptidase with thrombospondin type 1 motif, 8 0.810175
OTOF otoferlin 0.803948
C2ORF70 chromosome 2 open reading frame 70 0.792205
CLPTM1 cleft lip and palate associated transmembrane protein 1 0.789545
SGCZ sarcoglycan, zeta 0.77375
PSPH phosphoserine phosphatase 0.77291
CERS6 ceramide synthase 6 0.664902
WWOX WW domain containing oxidoreductase 0.628075
CACNA1D calcium channel, voltage-dependent, L type, alpha 1D subunit 0.616096
CSE1L CSE1 chromosome segregation 1-like (yeast) 0.60243
MGMT O-6-methylguanine-DNA methyltransferase 0.576144
EFCAB2 EF-hand calcium binding domain 2 0.570595
PTPN22 protein tyrosine phosphatase, non-receptor type 22 (lymphoid) 0.556152
RYR3 ryanodine receptor 3 0.554234
SEMA6D sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D 0.547225
MICAL2 microtubule associated monooxygenase, calponin and LIM domain containing 2 0.541061
ANXA10 annexin A10 0.537815
PKHD1 polycystic kidney and hepatic disease 1 (autosomal recessive) 0.536107
IMMP2L IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) 0.53513
ZFP28 ZFP28 zinc finger protein 0.533487
SLC30A8 solute carrier family 30 (zinc transporter), member 8 0.530188
DPYD dihydropyrimidine dehydrogenase 0.528284
RNF182 ring finger protein 182 0.524626
LDLRAD4 low density lipoprotein receptor class A domain containing 4 0.511702
DGKH diacylglycerol kinase, eta 0.502816