spastic cerebral palsy Gene Set

Dataset DISEASES Text-mining Gene-Disease Assocation Evidence Scores
Category disease or phenotype associations
Type disease
Description A cerebral palsy that is caused by damage in the outer layer of the brain, the cerebral cortex, which results in increased tone, or tension, in a muscle causing abnormal movements. (Human Disease Ontology, DOID_0050669)
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Genes

136 genes co-occuring with the disease spastic cerebral palsy in abstracts of biomedical publications from the DISEASES Text-mining Gene-Disease Assocation Evidence Scores dataset.

Symbol Name Standardized Value
ALDH3A2 aldehyde dehydrogenase 3 family, member A2 2.33755
RAB9B RAB9B, member RAS oncogene family 1.33589
PLP1 proteolipid protein 1 1.24602
OR13G1 olfactory receptor, family 13, subfamily G, member 1 1.19057
NETO2 neuropilin (NRP) and tolloid (TLL)-like 2 1.18023
RAB3GAP1 RAB3 GTPase activating protein subunit 1 (catalytic) 1.17292
CAPN15 calpain 15 1.10594
ASPSCR1 alveolar soft part sarcoma chromosome region, candidate 1 1.08621
SIRPA signal-regulatory protein alpha 1.08118
PQBP1 polyglutamine binding protein 1 1.06438
COL4A1 collagen, type IV, alpha 1 1.05765
HFM1 HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae) 1.0324
ELOVL4 ELOVL fatty acid elongase 4 0.964986
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa 0.930414
GABARAPL1 GABA(A) receptor-associated protein like 1 0.921323
SLC16A2 solute carrier family 16, member 2 (thyroid hormone transporter) 0.886799
PRAMEF20 PRAME family member 20 0.870825
GCH1 GTP cyclohydrolase 1 0.846259
FUCA2 fucosidase, alpha-L- 2, plasma 0.840525
F5 coagulation factor V (proaccelerin, labile factor) 0.821257
MOCS2 molybdenum cofactor synthesis 2 0.820847
SLC19A3 solute carrier family 19 (thiamine transporter), member 3 0.798692
FOXH1 forkhead box H1 0.785984
GAS7 growth arrest-specific 7 0.775341
AGK acylglycerol kinase 0.759824
FA2H fatty acid 2-hydroxylase 0.719654
FUCA1 fucosidase, alpha-L- 1, tissue 0.716425
C1QTNF5 C1q and tumor necrosis factor related protein 5 0.701526
LACTB lactamase, beta 0.693499
CCDC27 coiled-coil domain containing 27 0.691896
ARG1 arginase 1 0.681495
GLDC glycine dehydrogenase (decarboxylating) 0.681096
CPVL carboxypeptidase, vitellogenic-like 0.678701
TDG thymine-DNA glycosylase 0.658026
PPT2 palmitoyl-protein thioesterase 2 0.656441
SLC17A5 solute carrier family 17 (acidic sugar transporter), member 5 0.655254
SPTAN1 spectrin, alpha, non-erythrocytic 1 0.653671
OPHN1 oligophrenin 1 0.642221
LY96 lymphocyte antigen 96 0.630813
SUMF1 sulfatase modifying factor 1 0.629635
COL4A2 collagen, type IV, alpha 2 0.627672
ATL1 atlastin GTPase 1 0.62728
HSD17B10 hydroxysteroid (17-beta) dehydrogenase 10 0.623751
GNPAT glyceronephosphate O-acyltransferase 0.620226
MARCH7 membrane-associated ring finger (C3HC4) 7, E3 ubiquitin protein ligase 0.61162
PANK1 pantothenate kinase 1 0.611229
ICT1 immature colon carcinoma transcript 1 0.609276
BCL2L11 BCL2-like 11 (apoptosis facilitator) 0.606543
FKTN fukutin 0.606152
L1CAM L1 cell adhesion molecule 0.594064
LPIN1 lipin 1 0.55945
PNP purine nucleoside phosphorylase 0.554791
TPRG1L tumor protein p63 regulated 1-like 0.552851
SIX2 SIX homeobox 2 0.544318
THEM4 thioesterase superfamily member 4 0.541217
HLCS holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) 0.535022
MC2R melanocortin 2 receptor (adrenocorticotropic hormone) 0.530381
GPBAR1 G protein-coupled bile acid receptor 1 0.482464
CACNA1C calcium channel, voltage-dependent, L type, alpha 1C subunit 0.474877
ADGRV1 adhesion G protein-coupled receptor V1 0.474498
TAZ tafazzin 0.453339
TSKU tsukushi, small leucine rich proteoglycan 0.431144
PNPLA6 patatin-like phospholipase domain containing 6 0.424389
MIXL1 Mix paired-like homeobox 0.411283
EPGN epithelial mitogen 0.409414
ITPA inosine triphosphatase (nucleoside triphosphate pyrophosphatase) 0.406798
NMT1 N-myristoyltransferase 1 0.403811
HADH hydroxyacyl-CoA dehydrogenase 0.40008
FOLR1 folate receptor 1 (adult) 0.390397
PROCR protein C receptor, endothelial 0.388909
MLXIPL MLX interacting protein-like 0.377773
ASPA aspartoacylase 0.374809
PLIN1 perilipin 1 0.373698
EPB41L1 erythrocyte membrane protein band 4.1-like 1 0.359289
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 0.354499
POU2F3 POU class 2 homeobox 3 0.35082
AFF2 AF4/FMR2 family, member 2 0.341272
SLC6A7 solute carrier family 6 (neurotransmitter transporter), member 7 0.337242
CHKA choline kinase alpha 0.336876
OR10K2 olfactory receptor, family 10, subfamily K, member 2 0.336144
PRSS21 protease, serine, 21 (testisin) 0.332487
TBP TATA box binding protein 0.316456
CKM creatine kinase, muscle 0.302337
ATRX alpha thalassemia/mental retardation syndrome X-linked 0.290103
TOP3A topoisomerase (DNA) III alpha 0.28831
FOXL2 forkhead box L2 0.287593
LAX1 lymphocyte transmembrane adaptor 1 0.282582
SDF4 stromal cell derived factor 4 0.280082
BBS2 Bardet-Biedl syndrome 2 0.259124
MCM8 minichromosome maintenance complex component 8 0.253127
GLB1 galactosidase, beta 1 0.23945
TPH1 tryptophan hydroxylase 1 0.23945
COL6A1 collagen, type VI, alpha 1 0.236312
UROD uroporphyrinogen decarboxylase 0.228333
IKBKG inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma 0.227642
MUC6 mucin 6, oligomeric mucus/gel-forming 0.22454
GALC galactosylceramidase 0.220424
MSTN myostatin 0.212608
HSPG2 heparan sulfate proteoglycan 2 0.199033
APPL1 adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 0.189551
PAX8 paired box 8 0.189244
MYH6 myosin, heavy chain 6, cardiac muscle, alpha 0.188632
SCN2A sodium channel, voltage gated, type II alpha subunit 0.183248
CS citrate synthase 0.17896
CSF1R colony stimulating factor 1 receptor 0.178403
ALPPL2 alkaline phosphatase, placental-like 2 0.172291
ALPP alkaline phosphatase, placental 0.172038
ALPL alkaline phosphatase, liver/bone/kidney 0.171785
MAG myelin associated glycoprotein 0.168854
ETV3 ets variant 3 0.160203
TSPAN7 tetraspanin 7 0.158951
MLX MLX, MAX dimerization protein 0.157929
CALB1 calbindin 1, 28kDa 0.139981
MTHFR methylenetetrahydrofolate reductase (NAD(P)H) 0.139251
FBXW2 F-box and WD repeat domain containing 2 0.138861
CD59 CD59 molecule, complement regulatory protein 0.138348
BSG basigin (Ok blood group) 0.137465
ADRB2 adrenoceptor beta 2, surface 0.136429
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 0.136196
LTA lymphotoxin alpha 0.135942
SPTBN1 spectrin, beta, non-erythrocytic 1 0.135846
LMNA lamin A/C 0.135609
MECP2 methyl CpG binding protein 2 0.135366
PDE5A phosphodiesterase 5A, cGMP-specific 0.135129
SPTBN2 spectrin, beta, non-erythrocytic 2 0.134745
STXBP1 syntaxin binding protein 1 0.134408
AAAS achalasia, adrenocortical insufficiency, alacrimia 0.134294
SUOX sulfite oxidase 0.133498
NES nestin 0.13212
F2 coagulation factor II (thrombin) 0.13212
LCK LCK proto-oncogene, Src family tyrosine kinase 0.131297
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.130882
GUSB glucuronidase, beta 0.130669
MUC5B mucin 5B, oligomeric mucus/gel-forming 0.130621
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.129188
NPS neuropeptide S 0.127529